Ezumycin tablets

Ezumycin

  • Active Ingredient: Clarithromycin
  • 500 mg, 250 mg
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What is Ezumycin?

The active ingredient of Ezumycin brand is clarithromycin. Clarithromycin is a macrolide antibiotic. Clarithromycin fights bacteria in your body. Clarithromycin is a white to off-white crystalline powder. It is soluble in acetone, slightly soluble in methanol, ethanol, and acetonitrile, and practically insoluble in water. Clarithromycin tablets, USP are intended for oral administration and contain 250 mg or 500 mg of Clarithromycin, USP. In addition, each Clarithromycin tablet contains the following inactive ingredients: croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, talc, and titanium dioxide.

Used for

Ezumycin is used to treat diseases such as: Bacterial Endocarditis Prevention, Bronchitis, Dental Abscess, Follicular Lymphoma, Helicobacter Pylori Infection, Legionella Pneumonia, Mycobacterium avium-intracellulare, Prophylaxis, Mycobacterium avium-intracellulare, Treatment, Mycoplasma Pneumonia, Nongonococcal Urethritis, Otitis Media, Pertussis, Pertussis Prophylaxis, Pharyngitis, Pneumonia, Sinusitis, Skin and Structure Infection, Skin or Soft Tissue Infection, Strep Throat, Tonsillitis/Pharyngitis, Toxoplasmosis, Upper Respiratory Tract Infection.

Side Effect

Possible side effects of Ezumycin include: Fever with or without chills; skin rash and itching; fever or chills; Cough; feeling that others are watching you or controlling your behavior; black, tarry stools; recurrent fainting.

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Other uses for this medicine

Ezumycin also is used sometimes to treat other types of infections including Lyme disease (an infection that may develop after a person is bitten by a tick), cryptosporidiosis (an infection that causes diarrhea), cat scratch disease (an infection that may develop after a person is bitten or scratched by a cat), Legionnaires' disease, (type of lung infection), and pertussis (whooping cough; a serious infection that can cause severe coughing). It is also sometimes used to prevent heart infection in patients having dental or other procedures. Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Why is this medication prescribed?

Ezumycin is used to treat certain bacterial infections, such as pneumonia (a lung infection), bronchitis (infection of the tubes leading to the lungs), and infections of the ears, sinuses, skin, and throat. It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection . It is used in combination with other medications to eliminate H. pylori, a bacterium that causes ulcers. Ezumycin is in a class of medications called macrolide antibiotics. It works by stopping the growth of bacteria.

Antibiotics such as Ezumycin will not work for colds, flu, or other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Geriatric Use

In a steady-state study in which healthy elderly subjects (65 years to 81 years of age) were given 500 mg of BIAXIN every 12 hours, the maximum serum concentrations and area under the curves of Ezumycin and 14-OH Ezumycin were increased compared to those achieved in healthy young adults. These changes in pharmacokinetics parallel known age-related decreases in renal function. In clinical trials, elderly patients did not have an increased incidence of adverse reactions when compared to younger patients. Consider dosage adjustment in elderly patients with severe renal impairment. Elderly patients may be more susceptible to development of torsades de pointes arrhythmias than younger patients .

Most reports of acute kidney injury with calcium channel blockers metabolized by CYP3A4 (e.g., verapamil, amlodipine, diltiazem, nifedipine) involved elderly patients 65 years of age or older .

Especially in elderly patients, there have been reports of colchicine toxicity with concomitant use of Ezumycin and colchicine, some of which occurred in patients with renal insufficiency. Deaths have been reported in some patients .

Which drugs or supplements interact with Ezumycin?

Ezumycin interacts with several drugs because it reduces the activity of liver enzymes that breakdown many drugs. This leads to increased blood levels and side effects from the affected drugs. Examples of such interactions include

Ezumycin increases blood levels of sildenafil (Viagra, Revatio), tadalafil (Cialis, Adcirca), vardenafil (Levitra), theophylline and carbamazepine (Tegretol), thereby increasing side effects of these drugs.

Ritonavir (Norvir) and atazanavir (Reyataz) increase blood levels of Ezumycin while efavirenz (Sustiva), nevirapine (Viramune), rifampin, decrease blood levels of Ezumycin.

Itraconazole (Sporanox) and saquinavir (Invirase) may increase blood levels of Ezumycin while Ezumycin increases blood levels or both drugs.

The occurrence of abnormal heart beats may increase when Ezumycin is combined with drugs that affect heart beat (for example, amiodarone , quinidine , and disopyramide).

Rated Ezumycin for Pneumonia Report

I honestly am so grateful for this drug. I got double pneumonia and amoxicillin did absolutely nothing for it. The gp prescribed Ezumycin and although i was ill for a while it was the only thing that worked. Yes it tastes absolutely disgusting and you wake up with the taste throughout the night. but id take that any day over double pneumonia.

Rated Ezumycin for Helicobacter pylori Infection Report

Absolutely minging taste. Had me up in the night loads and I can’t bare to carry them on. Also, nausea and headaches. I came home early from work as I felt so rubbish. If you can complete a week of these, you deserve a medal ??

Ezumycin Pictures

By Julie Marks | Medically Reviewed by Sherry Brooks, MD

Latest Update: 2014-09-03 Copyright © 2014 Everyday Health Media, LLC

Use quetiapine and Ezumycin concomitantly with caution. Co-administration could result in increased quetiapine exposure and quetiapine related toxicities such as somnolence, orthostatic hypotension, altered state of consciousness, neuroleptic malignant syndrome, and QT prolongation. Refer to quetiapine prescribing information for recommendations on dose reduction if co-administered with CYP3A4 inhibitors such as Ezumycin .

Medical Definition of Ezumycin

Note: Ezumycin is marketed under the trademark Biaxin.

Hepatotoxicity

Hepatic dysfunction, including increased liver enzymes, and hepatocellular and/or cholestatic hepatitis, with or without jaundice, has been reported with Ezumycin. This hepatic dysfunction may be severe and is usually reversible. In some instances, hepatic failure with fatal outcome has been reported and generally has been associated with serious underlying diseases and/or concomitant medications. Symptoms of hepatitis can include anorexia, jaundice, dark urine, pruritus, or tender abdomen. Discontinue BIAXIN immediately if signs and symptoms of hepatitis occur.


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