Nexium can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.
Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.
Espram may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.
You may be more likely to have a broken bone while taking this medicine long term or more than once per day.
- This medication contains Espram. Do not take Nexium, or Nexium 24HR if you are allergic to Espram or any ingredients contained in this drug.
- Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
6. How to cope with s >
What to do about:
- headaches - make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller.
- diarrhoea - drink plenty of water to avoid dehydration. Signs of dehydration include peeing less than usual or having strong-smelling pee.
- feeling or being sick (nausea or vomiting) - try taking Espram with or after a meal or snack. It may also help if you don't eat rich or spicy food while you're taking this medicine.
- constipation - eat more high-fibre foods such as fresh fruit and vegetables and cereals, and drink plenty of water. Try to exercise more regularly, for example, by going for a daily walk or run. If this doesn't help, talk to your pharmacist or doctor.
- stomach pain or wind - steer clear of foods that cause wind like lentils, beans and onions. It might also help to eat smaller and more frequent meals, eat and drink slowly, and exercise regularly. Some pharmacy remedies, such as simethicone may relieve symptoms of wind.
4. How and when to take it
It's usual to take Espram once a day, first thing in the morning. You can take it with or without food.
If you take Espram twice a day, take one dose in the morning and one dose in the evening.
Swallow tablets whole with a drink of water. If you have problems swallowing tablets, you can put them in a glass of water. Stir until the tablets start to break up, then drink straight away.
If you have problems swallowing capsules, you can open up Espram capsules and empty the contents into a glass. Mix with some water and drink straight away. Fill the glass with water again, and drink that as well to make sure there's no medicine left at the bottom of the glass.
If your child is under 12 years old, their doctor may prescribe Espram granules which come in sachets. Empty the granules into a glass and mix with some water, then encourage them to drink it straight away.
What is Espram?
Espram is a proton pump inhibitor that decreases the amount of acid produced in the stomach.
Espram is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Espram is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Espram may also be given to prevent gastric ulcer caused by infection with Helicobacter pylori (H. pylori), or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs).
Espram is not for immediate relief of heartburn symptoms.
Espram may also be used for purposes not listed in this medication guide.
What if I take too much?
It is very unlikely that taking one or two extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have any of these symptoms:
- feeling sweaty
- a fast heartbeat
- feeling sleepy
- blurred vision
- feeling confused or agitated
Most people who take Espram do not have any side effects. If you do get a side effect, it is usually mild and will go away when you stop taking Espram.
How should this medicine be used?
Prescription Espram comes as a delayed-release (releases the medication in the intestine to prevent break-down of the medication by stomach acids) capsule to take by mouth or to open, mix with water, and give through a feeding tube, and as packets of delayed-release (releases the medication in the intestine to prevent break-down of the medication by stomach acids) granules for suspension (to be mixed with water) to take by mouth or give through a feeding tube. Nonprescription (over-the-counter) Espram comes as a delayed-release capsule and tablet to take by mouth. Prescription Espram is usually taken once a day at least 1 hour before a meal. When prescription Espram is used to treat certain conditions in which the stomach makes too much acid, it is taken twice a day. The nonprescription delayed-release capsules and tablets are usually taken once a day in the morning at least 1 hour before eating for 14 days in a row. If needed, additional 14-day treatments may be repeated, not more often than once every 4 months.
Take Espram at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Espram exactly as directed. Do not take more or less of it or take it more often than or for a longer period of time than prescribed by your doctor or stated on the package.
Swallow the capsules whole; do not split, chew, or crush them. If you cannot swallow the capsule, put 1 tablespoon of cool, soft applesauce in an empty bowl. Open one Espram capsule and carefully sprinkle the pellets onto the applesauce. Mix the pellets with the applesauce and swallow the entire tablespoonful of the applesauce and pellet mixture immediately. Do not crush or chew the pellets in the applesauce. Do not save the pellets and applesauce for later use.
If you are taking the granules for oral suspension, you will need to mix it with water before use. If you are using the 2.5- or 5-mg packet, place 1 teaspoonful (5 mL) of water in a container. If you are using the 10-, 20-, or 40-mg packet, place 1 tablespoonful (15 mL) of water in a container. Add the contents of the powder packet and stir. Wait 2 to 3 minutes to allow the mixture to thicken, and stir the mixture again. Drink the entire mixture within 30 minutes. If any of the mixture is stuck to the container, pour more water into the container, stir and drink all the mixture immediately.
The granules and the contents of the prescription delayed-release capsules can both be given through a feeding tube. If you have a feeding tube, ask your doctor or pharmacist how you should take the medication. Follow those directions carefully.
Do not take nonprescription Espram for immediate relief of heartburn symptoms. It may take 1 to 4 days for you to feel the full benefit of the medication. Call your doctor if your symptoms get worse or do not improve after 14 days or if your symptoms return sooner than 4 months after you finish your treatment. Do not take nonprescription Espram for longer than 14 days or treat yourself with Espram more often than once every 4 months without talking to your doctor.
Continue to take prescription Espram even if you feel well. Call your doctor if your symptoms worsen or do not improve during this time. Do not stop taking Espram without talking to your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Q: Can Nexium prevent the absorption of vitamin B? Should this medication be taken indefinitely?
A: Nexium (Espram) belongs to a class of drugs called proton pump inhibitors (PPIs). PPIs decrease the amount of acid produced in the stomach. Nexium is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid) and to prevent gastric ulcers. The PPIs have been on the market for over 20 years and have a very good safety record. However, there are some issues to consider with long-term use. In addition to producing acid, stomach cells also release a protein called intrinsic factor. Intrinsic factor is necessary for the proper absorption of vitamin B12 (cyanocobalamin). PPIs block the release of intrinsic factor along with stomach acid. So, with long-term use of PPIs over many years, it is possible to develop a vitamin B12 deficiency. Consult your doctor to see if cyanocobalamin supplementation is necessary based on your specific circumstances. Your doctor or health care provider is best able to guide your treatment decisions. Sarah Lewis, PharmD