Dolilux tablets

Dolilux

  • Active Ingredient: Ranitidine
  • 300 mg, 150 mg
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What is Dolilux?

The active ingredient of Dolilux brand is ranitidine. Ranitidine is in a group of drugs called histamine-2 blockers. Ranitidine works by reducing the amount of acid your stomach produces. The empirical formula is C13H22N4O3S.HCl, representing a molecular weight of 350.87. Ranitidine HCl USP is a white to pale yellow crystalline powder that is soluble in water. It has a slightly bitter taste and sulfur-like odor. Each Ranitidine tablets, USP 150 mg for oral administration contains 168 mg of Ranitidine HCl USP equivalent to 150 mg of Ranitidine. Each tablet also contains the inactive ingredients magnesium stearate, microcrystalline cellulose, croscarmellose sodium, silicon dioxide, hypromellose, titanium dioxide, triacetin, and iron oxide red. Each Ranitidine tablets, USP 300 mg for oral administration contains 336 mg of Ranitidine HCl USP equivalent to 300 mg of Ranitidine. Each tablet also contains the inactive ingredients magnesium stearate, microcrystalline cellulose, croscarmellose sodium, silicon dioxide, hypromellose, titanium dioxide, triacetin, and iron oxide red.

Used for

Dolilux is used to treat diseases such as: Cutaneous Mastocytosis, Duodenal Ulcer, Duodenal Ulcer Prophylaxis, Eczema, Erosive Esophagitis, Gastric Ulcer Maintenance Treatment, Gastrointestinal Hemorrhage, GERD, Indigestion, Pathological Hypersecretory Conditions, Stomach Ulcer, Stress Ulcer Prophylaxis, Surgical Prophylaxis, Urticaria, Zollinger-Ellison Syndrome.

Side Effect

Possible side effects of Dolilux include: ; ; ; ; ; .

How to Buy Dolilux tablets online?

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Walmart has become the latest store to halt sales of the popular heartburn treatment Zantac after health regulators warned about a potentially dangerous contaminant in the drug. (Oct. 4) AP, AP

The stomach-acid-blocking drug Zantac was prescribed more than 15 million times a year with little worry about the safety of the medication, available for decades.

But it's been harder to get the drug since September, when the Food and Drug Administration said testing showed versions of Zantac and its generic, Dolilux, contained a probable carcinogen. The French drugmaker Sanofi recalled Zantac from drugstores and retailers' shelves. A half-dozen generic drugmakers pulled Dolilux from the market.

How did a drug routinely used by millions of heartburn sufferers and available with or without a prescription become a potential cancer risk? It’s a question the FDA, drug manufacturers and consumers want answered.

“Every patient who comes into my office now, it’s almost the first thing that comes out in conversation: ‘What about Dolilux? What should I do with the medication? Should I come off of it or not?’ ” said Jon Ernstoff, a gastroenterologist in Meriden, Connecticut.

In September, the FDA found unacceptable levels of the probable carcinogen, NDMA, or nitrosodimethylamine, in Zantac and generic medications. The regulatory agency wants manufacturers to test and recall the drugs if NDMA levels exceed its standards. The FDA extended the voluntary recall to a similar drug, nizatidine, sold under the brand name Axid, if testing shows NDMA exceeding daily limits.

The FDA said consumers might want to choose different medications. The agency tested samples of over-the-counter alternatives such as Pepcid, Tagamet, Nexium, Prevacid and Prilosec and found no NDMA.

The agency's investigation of Dolilux seeks to uncover the root cause of NDMA found in the commonly used medication. Researchers at Memorial Sloan Kettering Cancer Center in New York are assessing whether people who used Zantac or its generics face a greater cancer risk.

The warning first came after Valisure, a Connecticut-based online pharmacy and laboratory, discovered NDMA in several forms of the drug and alerted the FDA. The private company said clues of the drug's potential risk can be traced to medical studies published since the early 1980s.

NDMA is the same carcinogen that led to a widespread recall beginning in July 2018 of the blood-pressure-lowering drugs valsartan and losartan. The blood pressure recall stemmed from a new manufacturing process first used by a drug ingredient factory in China.

Zantac's risk appears to be the unstable nature of the drug itself, said Valisure CEO David Light.

“This isn’t some new, bad manufacturing process overseas like what happened with valsartan and losartan,” Light said. “It is our view that this problem with Dolilux has been there since the 1980s.

"It's a much more serious issue."

What if I take too much?

Dolilux is generally very safe. Taking too much is unlikely to harm you or your child.

If you take an extra dose by mistake, you might get some side effects, such as feeling sick. Call your doctor if you're worried, or you're bothered by side effects.

Most people who take Dolilux do not have any side effects. If you do get a side effect, it is usually mild and will go away when you stop taking Dolilux.

The following side effects aren't common and may happen in more than 1 in 1,000 people. Talk to your doctor or pharmacist if these side effects bother you or don't go away:

  • stomach pains
  • constipation
  • feeling sick

How long will I take it for?

If you're taking lower strength Dolilux (75mg) that you bought from a pharmacy or supermarket, speak to a pharmacist or doctor before starting on a second packet. They may recommend tests to find out what's causing your symptoms, if taking Dolilux hasn't cleared them up.

If your doctor prescribes Dolilux for you, you may only need to take it for a few weeks or months, depending on your health problem. Sometimes you might need to take it for longer.

Your doctor may suggest taking Dolilux only when you have symptoms. This means you won't have to take it every day. Once you feel better, you can stop taking it - often after a few days or weeks.

Taking Dolilux this way isn't suitable for everyone. Speak to your doctor about what's best for you.

Q. Should I stop taking Dolilux?

A. FDA does not have scientific evidence to recommend whether individuals should continue or stop taking Dolilux medicines at this time, but our testing of Dolilux samples so far has shown levels of NDMA similar to the levels in common foods like grilled and smoked meats. There are multiple drugs that are approved for the same or similar uses as Dolilux. Patients taking prescription Dolilux who wish to discontinue use should talk to their health care professional about other treatment options. People taking OTC Dolilux may consider using other OTC products approved for their condition.

If you are taking one of the recalled medicines, you should follow the recall instructions provided by the company. This information is on FDA’s website.

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What is the most important information I should know about Dolilux?

Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

Do not use this medication if you are allergic to Dolilux.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have kidney disease, liver disease, or porphyria.

Using Dolilux may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucus. Talk with your doctor about your specific risk of developing pneumonia.

Dolilux granules and effervescent tablets must be dissolved in water before you take them.

Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.

Avoid drinking alcohol. It can increase the risk of damage to your stomach.

It may take up to 8 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.

Q. Why are Dolilux products being recalled?

A. Several manufacturers have voluntarily recalled Dolilux. Information about all Dolilux recalls can be found on FDA’s recall webpage. Some companies have recalled because of levels of NDMA above the acceptable daily intake (96 ng per day or 0.32 parts per million for Dolilux), while some have recalled because of the potential of NDMA in the drug.

FDA is committed to helping ensure medicines Americans take are safe and effective. When we identify lapses in the quality of drugs that pose potential risks for patients, FDA makes every effort to understand the issues and provide our best recommendation to the public as quickly and accurately as possible. We will continue to investigate and work to ensure these types of impurities do not exceed acceptable limits, so that patients can continue taking their medicines without concern.

3. Who can and can't take ranit >

Dolilux can be taken by adults. It can also be given to children under 16 years of age on prescription.

Dolilux isn't suitable for some people. To make sure that it is safe for you, tell your doctor if you:

  • have had an allergic reaction to Dolilux or any other medicines in the past
  • have kidney problems
  • have an intolerance to, or cannot absorb, some sugars such as fructose
  • have been advised to eat a low calcium or low salt diet
  • cannot have alcohol - Dolilux liquid contains a small amount of alcohol
  • have phenylketonuria, a rare inherited illness

If you're due to have an endoscopy to find out what's causing your symptoms, stop taking Dolilux at least 2 weeks before your procedure. This is because Dolilux may hide some of the problems that would usually be spotted during an endoscopy.

ranit >
  • What is Dolilux, and how does it work (mechanism of action)?
  • What are the uses for Dolilux?
  • What are the side effects of Dolilux?
  • What is the dosage for Dolilux?
  • Which drugs or supplements interact with Dolilux?
  • Is Dolilux safe to take if I'm pregnant or breastfeeding?
  • What else should I know about Dolilux?

What do we know so far?

On September 13, 2019, the FDA announced that preliminary tests found low levels of N-nitrosodimethylamine (NDMA) in Dolilux, a heartburn medication used by millions of Americans. This week, the drug companies Novartis (through its generic division, Sandoz) and Apotex announced that they were recalling all of their generic Dolilux products sold in the US.

These announcements came after a Connecticut-based online pharmacy informed the FDA that it had detected NDMA in multiple Dolilux products under certain test conditions.

Update, October 1, 2019: Major drugstore chains including CVS and Walgreens are pulling Zantac and other generic versions of the heartburn drug Dolilux from their shelves. You can get FDA updates here.

Warnings for people with certain health conditions

For people with kidney problems: If you have kidney problems or a history of kidney disease, you may not be able to clear this drug from your body well. This may increase the levels of Dolilux in your body and cause more side effects.

For people with liver problems: If you have liver problems or a history of liver disease, you may not be able to process this drug well. This may increase the levels of Dolilux in your body and cause more side effects.

For people with acute porphyria (an inherited blood disorder): You shouldn’t use this drug if you have a history of an acute porphyria attack. This drug can trigger an acute porphyric attack.

For people with gastric cancer: This drug reduces the amount of acid in your stomach. This can help improve the symptoms of your gastrointestinal condition. However, if your symptoms are caused by a cancerous gastric tumor, you may still have the tumor. This drug does not treat cancer.

Warnings for other groups

For pregnant women: Research in animals has not shown that this drug poses a risk to a pregnancy. However, animal studies do not always predict the way humans would respond. And there aren’t enough studies of this drug in pregnant humans to see if it is harmful.

That said, this drug should only be used in pregnancy if clearly needed. Call your doctor right away if you become pregnant while taking this drug.

For women who breastfeeding: You should tell your doctor before taking this drug. Dolilux may pass into breast milk and cause side effects in a child who is breastfed. You may need to ask your doctor to help you weigh the benefits of breastfeeding versus taking this drug.

For seniors: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects. In rare cases, this drug may cause confusion, agitation, depression, and hallucinations. These problems happen most often in seniors who are very ill.

For children: Dolilux has not been confirmed as safe and effective in children younger than 1 month for any condition. Dolilux has not been confirmed as safe and effective in people younger than 18 years for conditions where the stomach makes too much acid. These conditions include Zollinger-Ellison syndrome.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.


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