Docraniti syrup


  • Active Ingredient: Ranitidine
  • 300 mg, 150 mg
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What is Docraniti?

The active ingredient of Docraniti brand is ranitidine. Ranitidine is in a group of drugs called histamine-2 blockers. Ranitidine works by reducing the amount of acid your stomach produces. The empirical formula is C13H22N4O3S.HCl, representing a molecular weight of 350.87. Ranitidine HCl USP is a white to pale yellow crystalline powder that is soluble in water. It has a slightly bitter taste and sulfur-like odor. Each Ranitidine tablets, USP 150 mg for oral administration contains 168 mg of Ranitidine HCl USP equivalent to 150 mg of Ranitidine. Each tablet also contains the inactive ingredients magnesium stearate, microcrystalline cellulose, croscarmellose sodium, silicon dioxide, hypromellose, titanium dioxide, triacetin, and iron oxide red. Each Ranitidine tablets, USP 300 mg for oral administration contains 336 mg of Ranitidine HCl USP equivalent to 300 mg of Ranitidine. Each tablet also contains the inactive ingredients magnesium stearate, microcrystalline cellulose, croscarmellose sodium, silicon dioxide, hypromellose, titanium dioxide, triacetin, and iron oxide red.

Used for

Docraniti is used to treat diseases such as: Cutaneous Mastocytosis, Duodenal Ulcer, Duodenal Ulcer Prophylaxis, Eczema, Erosive Esophagitis, Gastric Ulcer Maintenance Treatment, Gastrointestinal Hemorrhage, GERD, Indigestion, Pathological Hypersecretory Conditions, Stomach Ulcer, Stress Ulcer Prophylaxis, Surgical Prophylaxis, Urticaria, Zollinger-Ellison Syndrome.

Side Effect

Possible side effects of Docraniti include: ; ; ; ; .

How to Buy Docraniti syrup online?

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What other drugs will affect Docraniti?

Before taking Docraniti, tell your doctor if you are taking triazolam (Halcion). You may not be able to use Docraniti, or you may need dosage adjustments or special tests during treatment.

There may be other drugs that can interact with Docraniti. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.


GENERIC NAME(S): Docraniti Hcl

Docraniti is used to treat ulcers of the stomach and intestines and prevent them from coming back after they have healed. This medication is also used to treat certain stomach and throat (esophagus) problems (such as erosive esophagitis, gastroesophageal reflux disease-GERD, Zollinger-Ellison syndrome). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as cough that doesn't go away, stomach pain, heartburn, and difficulty swallowing. Docraniti belongs to a class of drugs known as H2 blockers.

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For Healthcare Professionals

Applies to Docraniti: compounding powder, injectable solution, intravenous solution, oral capsule, oral granule effervescent, oral syrup, oral tablet, oral tablet effervescent

Q: Is it safe to take Zantac during the first trimester of pregnancy?

A: Zantac (Docraniti) is classified as pregnancy Category B, which means that it has been tested in pregnant lab animals and has not been shown to cause any damage to the fetus in those animals. However, it has not been tested in humans and there is a lack of documentation to form any conclusions as to whether it will interfere with the development of a human fetus. Please consult your ob/gyn about his or her preferential treatments for excess stomach acid. Feel free to visit us here: // M. Curley, PharmD

Q. Should I stop taking Docraniti?

A. FDA does not have scientific evidence to recommend whether individuals should continue or stop taking Docraniti medicines at this time, but our testing of Docraniti samples so far has shown levels of NDMA similar to the levels in common foods like grilled and smoked meats. There are multiple drugs that are approved for the same or similar uses as Docraniti. Patients taking prescription Docraniti who wish to discontinue use should talk to their health care professional about other treatment options. People taking OTC Docraniti may consider using other OTC products approved for their condition.

If you are taking one of the recalled medicines, you should follow the recall instructions provided by the company. This information is on FDA’s website.

How long will I take it for?

If you're taking lower strength Docraniti (75mg) that you bought from a pharmacy or supermarket, speak to a pharmacist or doctor before starting on a second packet. They may recommend tests to find out what's causing your symptoms, if taking Docraniti hasn't cleared them up.

If your doctor prescribes Docraniti for you, you may only need to take it for a few weeks or months, depending on your health problem. Sometimes you might need to take it for longer.

Your doctor may suggest taking Docraniti only when you have symptoms. This means you won't have to take it every day. Once you feel better, you can stop taking it - often after a few days or weeks.

Taking Docraniti this way isn't suitable for everyone. Speak to your doctor about what's best for you.

Studies pointing to risk date to 1980s

In 2016, Stanford University researchers tested urine samples of 10 people who took a 150-milligram tablet of Zantac and found NDMA levels far greater than the FDA's daily limits.

William Mitch is a Stanford University professor of civil and environmental engineering who studies wastewater converted to drinking water. He said his Zantac-urine study was a "chance finding from a peripheral field" after a study on potential NDMA contamination in drinking water.

He said it should be followed by a more robust study using the FDA's testing methods.

"The challenge is there's so much concern about cancer risk. Could you get approval from someone to eat a Zantac and collect the urine sample?" Mitch said, noting such a request would be odd and ethically challenging, given the drug has a known carcinogen and remains on the market.

Lior Braunstein, a Memorial Sloan Kettering oncologist and researcher, is studying Docraniti and cancer risk. He does not want to discuss the study until the findings are published in a peer-reviewed journal, according to Caitlin Hool, a hospital spokeswoman.

Light said studies conducted in the 1980s raised concern about potential safety risks. In a citizen petition to the FDA, Valisure said Zantac's originator, Glaxo Research Group, conducted its own study in 1987 "after numerous studies raised concerns" about Docraniti.

The Glaxo study examined stomach contents of people who took the drug. It found people had no significant increase in nitrosamines such as NDMA within 24 hours of taking Docraniti.

Light said the study's testing methods were less accurate and researchers discarded stomach samples that contained Docraniti. Without those samples, researchers would not find NDMA or nitrosamines that form as a result of taking the drug, Light said.

Light said the Stanford study and his lab's own analysis shows the potential health risk for people who took the drug.

"The negative effect of exposure to this drug and its formation of NDMA is something that has created a huge public health problem," he said, "and we’re going to be dealing with it going forward."

What is the dosage for Docraniti?

Docraniti may be taken with or without food.

  • Usual oral doses for treating ulcers and GERD are 150 mg twice daily or 300 mg at bedtime. The maintenance dose is 150 mg daily.
  • Erosive esophagitis is treated with 150 mg 4 times daily.
  • Zollinger-Ellison syndrome may be treated with as much as 6 g daily.
  • Heartburn is treated with 75 mg or 150 mg once or twice daily 30-60 minutes before consuming meals or beverages that cause heartburn.

Self-medication should not last longer than 2 weeks unless advised by a physician.

Serious allergic reaction

In rare cases, it's possible to have a serious allergic reaction (anaphylaxis) to Docraniti.

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