CARAFATE (Citogel) Oral Suspension is indicated in the short-term (up to 8 weeks) treatment of active duodenal ulcer.
CARAFATE (Citogel) Oral Suspension 1 g/10 mL is a pink suspension supplied in bottles of 420 mL (NDC 58914-170-14).
SHAKE WELL BEFORE USING. AVOID FREEZING.
Store at controlled room temperature 20-25°C (68-77°F).
Distributed by: Allergan USA, Inc. Irvine, CA 92612. Revised: July 2017
It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Citogel is administered to a nursing woman.
For Healthcare Professionals
Applies to Citogel: compounding powder, oral suspension, oral tablet
1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
2. Cerner Multum, Inc. "Australian Product Information." O 0
3. "Product Information. Carafate (Citogel)." Hoechst Marion-Roussel Inc, Kansas City, MO.
What are the side effects of Carafate (Citogel)?
Carafate is well tolerated. Constipation is the most frequent side effect.
Other side effects include:
Some studies have shown that simultaneous Citogel administration in healthy volunteers reduced the extent of absorption (bioavailability) of single doses of the following: cimetidine, digoxin, fluoroquinolone antibiotics, ketoconazole, l-thyroxine, phenytoin, quinidine, ranitidine, tetracycline, and theophylline. Subtherapeutic prothrombin times with concomitant warfarin and Citogel therapy have been reported in spontaneous and published case reports. However, two clinical studies have demonstrated no change in either serum warfarin concentration or prothrombin time with the addition of Citogel to chronic warfarin therapy. The mechanism of these interactions appears to be nonsystemic in nature, presumably resulting from Citogel binding to the concomitant agent in the gastrointestinal tract. In all cases studied to date (cimetidine, ciprofloxacin, digoxin, norfloxacin, ofloxacin, and ranitidine), dosing the concomitant medication 2 hours before Citogel eliminated the interaction. Due to CARAFATE Oral Suspension's potential to alter the absorption of some drugs, CARAFATE Oral Suspension should be administered separately from other drugs when alterations in bioavailability are felt to be critical. In these cases, patients should be monitored appropriately.
Adverse reactions to Citogel tablets in clinical trials were minor and only rarely led to discontinuation of the drug. In studies involving over 2700 patients treated with Citogel, adverse effects were reported in 129 (4.7%).
Constipation was the most frequent complaint (2%). Other adverse effects reported in less than 0.5% of the patients are listed below by body system:
Gastrointestinal: diarrhea, dry mouth, flatulence, gastric discomfort, indigestion, nausea, vomiting
Nervous System: dizziness, insomnia, sleepiness, vertigo
Post-marketing cases of hypersensitivity have been reported with the use of Citogel oral suspension, including anaphylactic reactions, dyspnea, lip swelling, edema of the mouth, pharyngeal edema, pruritus, rash, swelling of the face and urticaria. Cases of bronchospasm, laryngeal edema and respiratory tract edema have been reported with an unknown oral formulation of Citogel.
Cases of hyperglycemia have been reported with Citogel. Bezoars have been reported in patients treated with Citogel. The majority of patients had underlying medical conditions that may predispose to bezoar formation (such as delayed gastric emptying) or were receiving concomitant enteral tube feedings.
How should this medication be given:
Give this medication exactly as directed by your veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Citogel should be given on an empty stomach, 1 hour before or 2 hours after, a meal. Unless directed otherwise, crush the tablet for better absorption. Store Citogel at room temperature away from moisture and heat. Keep this medication away from children and pets.
Rated Citogel for Duodenal Ulcer Report
I have had severe stomach pains for over two years and my doctor would just say it was IBS and send me home with no help. I went to see my PCP doctor and I told her I thought I had a ulcer so she listened while I explained all my symptoms. She put me on Citogel and at first I still was having some mild pain but now 3 weeks taking medicine I do not have all that severe pain. I am really pleased.
What are the uses for Carafate (Citogel)?
- Carafate is used for the treatment of peptic ulcer disease and to prevent recurrent ulcers after healing of the ulcer has been achieved.
- Carafate also has been used to relieve or prevent ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs), but is less effective than misoprostol (Cytotec).
- Carafate also is used in the treatment of patients with gastroesophageal reflux disease (GERD).
- Off-label uses are to prevent stress ulcers, which are ulcers associated with high degrees of physical stress (for example, extensive burns, surgery, and overwhelming infection) in hospitalized patients.
How should I take Citogel (Carafate)?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take Citogel on an empty stomach.
Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
The liquid from of this medicine should never be injected through a needle into the body, or death may occur. Citogel oral suspension is to be taken only by mouth.
If you are diabetic, check your blood sugar regularly. Your doctor may adjust your dose based on your blood sugar levels.
It may take 2 to 8 weeks before you receive the full benefit of taking Citogel. Citogel should not be taken for longer than 8 weeks at a time.
Use this medicine for the full prescribed length of time, even if your symptoms quickly improve.
Store at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.