Outcome and Management
The minor serum aminotransferase elevations that appear during therapy with Biclar are usually benign, asymptomatic and resolve rapidly whether or not Biclar is stopped. The acute hepatic injury with jaundice, however, can be prolonged and troublesome and lead to loss of intrahepatic bile ducts and vanishing bile duct syndrome. Rare instances of fatality from Biclar induced liver disease have been reported. It is unclear whether there is cross sensivity to hepatic injury about the different macrolide antibiotics, but after severe injury from one macrolide, it is prudent to avoid use of the others.
Rated Biclar for Sinusitis Report
A real rollercoaster. I've taken this about 8 times for sinus infections, that's a total of about 16 weeks divided over the past 5 years. Days 1 to 2 are generally OK in fact quick improvement IF you have yours directly after breakfast, and the other directly after dinner. 12 hours apart. 250 x 2. I once tried 500 x 2 and it was WAY too strong. Made me very anxious. At 250 x 2 a day you are wiped out tired for day 3/4/5/6 but drink water and that helps. I think caffeine could make things worse. In short, it's a very hard slog, you'll probably need time off work e.g. 3 or 4 days but you'll feel better if you do the 2/3 weeks for sinus infection. If really bad I've heard some people do 4 weeks. Anyways, it works for me but I've also decided to get allergy testing and maybe rhinolight treatment or immuno shots. Try Clarithromycic but if you feel too bad stop, or reduce to 250 x 2 a day if you're on higher. Oh and I take Valerian Root capsules 400mg x 3 a day to help with the anxiety side effects -- they work! Good luck and happy sinuses!
Helicobacter Pylori Infection And Duodenal Ulcer Disease
BIAXIN Filmtab is given in combination with other drugs in adults as described below to eradicate H. pylori. The eradication of H. pylori has been demonstrated to reduce the risk of duodenal ulcer recurrence .
- BIAXIN Filmtab in combination with amoxicillin and PREVACID (lansoprazole) or PRILOSEC (omeprazole) Delayed-Release Capsules, as triple therapy, are indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or five-year history of duodenal ulcer) to eradicate H. pylori.
- BIAXIN Filmtab in combination with PRILOSEC (omeprazole) capsules are indicated for the treatment of patients with an active duodenal ulcer associated with H. pylori infection. Regimens which contain BIAXIN Filmtab as the single antibacterial agent are more likely to be associated with the development of Biclar resistance among patients who fail therapy. Biclar-containing regimens should not be used in patients with known or suspected Biclar resistant isolates because the efficacy of treatment is reduced in this setting.
What is Biclar?
Biclar is a macrolide broad-spectrum antibiotic – it helps to clear up infections caused by a wide variety of bacteria.
Biclar is available as tablets (250mg or 500mg), modified release tablets (500mg), oral solution (125mg/5ml or 250mg/5ml) and powder for infusion.
Biclar is available under the brand name of Klaricid.
Biaxin is the brand name for Biclar in America.
Changes in laboratory values with possible clinical significance in patients taking BIAXIN and omeprazole in four randomized double-blind trials in 945 patients are as follows:
Hepatic: elevated direct bilirubin 1 A numerically higher number of primary outcome events in patients randomized to receive Biclar was observed with a hazard ratio of 1.06 (95% confidence interval 0.98 to 1.14). However, at follow-up 10 years post-treatment, there were 866 (40%) deaths in the Biclar group and 815 (37%) deaths in the placebo group that represented a hazard ratio for all-cause mortality of 1.10 (95% confidence interval 1.00 to 1.21). The difference in the number of deaths emerged after one year or more after the end of treatment.
The cause of the difference in all-cause mortality has not been established. Other epidemiologic studies evaluating this risk have shown variable results .
Rated Biclar for Skin And Skin Structure Infections Report
Omg i will never take this again.I was bitten by a cat and my finger did swell 2x the size & within 4 hours,was weeping gloop.Nurse cleaned & strapped it & dr gave me this nasty pill. i am allergic to penicillin so this was next on list.1st & 2nd dose was ok then felt awful & felt the need2eat but that made me feel worse.That day,out of 24 hours,i slept for 19 hours.I went super cold,then melting & repeat & also then had the most disgusting taste in my mouth.I didnt take anymore-my finger may fall off lol but at least i now feel human
Rated Biclar for Streptococcus Pneumoniae Report
I wish I had read other reviews before having taken Biclar. I took it 8 1/2 years ago and stuck it out for about half of my 14 day prescription. I had severe anxiety, hallucinations, severe claustrophobia, noise intolerance, raw skin under my eyes, racing heartbeat, peripheral bounding pulse, and severe insomnia. 8 1/2 years later, I still have anxiety, peripheral bounding pulse, and insomnia. Do not take this drug. I do not usually write reviews like this, but this drug has changed my life. I wish I could go back and take something different. I am finally finding treatment that looks hopeful in helping combat these side effects.
Rated Biclar for Bronchitis- acute Report
Please do not take this drug. I had to end the course after 3- 500mg tablets, severe side effects, nightmares, insomnia, MUSCLE SPASMS, and these all can be PERMANENT as in forever lifelong symptoms. Many are living with life long symptoms that will SHORTEN YOUR LIFE SPAN. Serious issues such as change to rythm of the heart and CNS damage, Chronic Fatigue and a COGNITIVE IMPAIRMENTS that can be PERMANENT. I am just one of those unlucky enough to go for a doctor begging for help only to be poisned.
Biclar (Biaxin, Biaxin XL) is an antibiotic drug prescribed for the treatment of a large variety of bacterium. Biclar is used to treat infections of the middle ear, tonsils, throat, larynx, bronchioles, lungs, and skin. Side effects, drug interactions, warnings and precautions, and pregnancy safety information should be reviewed prior to taking any medication.
Rated Biclar for Tonsillitis/Pharyngitis Report
I wouldn't recommend this tablet. Massive to swallow when your throat is almost closed over. Taken them for three days and am givng up. Awful bitter metallic taste in my mouth and then today i felt the need to poop twice both times the toilet water was almost red with blood like a heavy period would be. Terrified of wgat these tablets are doing inside our bodies. Researched side effects which say symptoms should go away 3 days after stopping. Never again . Awful tablet.
2. Key facts
- It's usual to take Biclar twice a day: once in the morning and once in the evening.
- Some people take slow-release Biclar tablets. These are taken once a day.
- For most infections, you should feel better within a few days.
- The most common side effects of Biclar are feeling or being sick, stomach cramps, and diarrhoea.
- You can drink alcohol while taking Biclar.
- Clarithromcyin is also called by the brand names Clarie XL, Klaricid, Klaricid XL and Xetinin XL.