Antepsin tablets


  • Active Ingredient: Sucralfate
  • 1000 mg
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What is Antepsin?

The active ingredient of Antepsin brand is sucralfate. Sucralfate is an anti-ulcer medication.

Used for

Antepsin is used to treat diseases such as: Duodenal Ulcer, Duodenal Ulcer Prophylaxis, GERD, Hyperphosphatemia of Renal Failure, Stomach Ulcer, Stomatitis, Stress Ulcer Prophylaxis.

Side Effect

Possible side effects of Antepsin include: dryness of mouth; Drowsiness; Backache; skin rash, hives, or itching; indigestion; stomach cramps or pain.

How to Buy Antepsin tablets online?

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What should I discuss with my veterinarian before giving Antepsin to my pet:

Tell your veterinarian if your pet is constipated or has megacolon. Tell your veterinarian if your pet is pregnant or nursing.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to Antepsin.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.


Antepsin is only minimally absorbed from the gastrointestinal tract. The small amounts of the sulfated disaccharide that are absorbed are excreted primarily in the urine. Although the mechanism of Antepsin's ability to accelerate healing of duodenal ulcers remains to be fully defined, it is known that it exerts its effect through a local, rather than systemic, action. The following observations also appear pertinent:

  1. Studies in human subjects and with animal models of ulcer disease have shown that Antepsin forms an ulcer-adherent complex with proteinaceous exudate at the ulcer site.
  2. In vitro, a Antepsin-albumin film provides a barrier to diffusion of hydrogen ions.
  3. In human subjects, Antepsin given in doses recommended for ulcer therapy inhibits pepsin activity in gastric juice by 32%.

In vitro, Antepsin adsorbs bile salts.

These observations suggest that Antepsin's antiulcer activity is the result of formation of an ulcer-adherent complex that covers the ulcer site and protects it against further attack by acid, pepsin, and bile salts. There are approximately 14 to 16 mEq of acid-neutralizing capacity per 1 g dose of Antepsin.

How should this medication be given:

Give this medication exactly as directed by your veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Antepsin should be given on an empty stomach, 1 hour before or 2 hours after, a meal. Unless directed otherwise, crush the tablet for better absorption. Store Antepsin at room temperature away from moisture and heat. Keep this medication away from children and pets.

What is Antepsin?

Antepsin is a prescription medication used in dogs, cats, and horses to treat ulcers. Although Antepsin is not FDA-approved for use in veterinary medicine, it is a commonly accepted practice for veterinarians to prescribe this medication for dogs, cats, and horses. Antepsin requires a prescription from your veterinarian, and is sold per tablet.

Dogs, Cats, and Horses

Antepsin dosing information

Usual Adult Dose for Duodenal Ulcer:

1 g orally 4 times a day-Duration of therapy: 4 to 8 weeks

Comments:-Each dose should be taken on an empty stomach.-For most patients, treatment should continue for 4 to 8 weeks; however, treatment may be stopped early if healing is demonstrated on x-ray/endoscopic tests.-Antacids may be given, but use should be separated by at least 30 minutes.

Use: Short-term treatment of active duodenal ulcers

Usual Adult Dose for Duodenal Ulcer Prophylaxis:

Oral Tablets: 1 g orally 2 times a day-Duration of therapy: Up to 1 year

Comments:-Each dose should be taken on an empty stomach.-Controlled studies did not extend beyond 12 months.

Use: Maintenance therapy for patients after healing of acute duodenal ulcers



This medication is used to treat and prevent ulcers in the intestines. Antepsin forms a coating over ulcers, protecting the area from further injury. This helps ulcers heal more quickly.

What is Carafate (Antepsin)?

Carafate is a unique oral drug that is used for treating ulcers of the upper gastrointestinal tract.

What should I avoid while taking Antepsin (Carafate)?

Avoid taking any other medications within 2 hours before or after you take Antepsin. Antepsin can make it harder for your body to absorb other medications you take by mouth.

Ask your doctor before using an antacid, and use only the type your doctor recommends. Some antacids can make it harder for Antepsin to work in your stomach. Avoid taking an antacid within 30 minutes before or after taking Antepsin.


Before taking Antepsin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, swallowing problems (such as difficulty swallowing, history of aspiration), stomach/intestine problems (e.g., delayed gastric emptying), tube feeding, use of a breathing tube (tracheotomy).

Kidney function declines as you grow older. This medication contains aluminum, which is normally removed by your kidneys. Therefore, elderly people may be at greater risk for developing high aluminum levels while using this drug with other products that contain aluminum (e.g., antacids).

If you are pregnant, tell your doctor before using Antepsin.

It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.

What are the possible side effects of Antepsin:

If any of the following serious side effects occur, stop giving Antepsin and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips; tongue or face; hives). Antepsin may cause constipation. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.

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