Which drugs or supplements interact with Antac?
Antac, like other drugs that reduce stomach acid, may interfere with the absorption of drugs that require acid for adequate absorption. Examples include iron salts (for example iron sulphate), itraconazole (Sporanox), and ketoconazole (Nizoral, Extina, Xolegel, Kuric).
What Is Zantac (Ranit >
Zantac is the brand name of the drug Antac, which is used to treat stomach and digestive problems.
The drug is prescribed for conditions such as gastroesophageal reflux disease (GERD), ulcers, Zollinger-Ellison syndrome, erosive esophagitis, upper gastrointestinal bleeding, heartburn, and other conditions where the stomach produces too much acid.
It's sometimes used to prevent stress ulcers, aspiration of stomach acid during anesthesia, and stomach damage caused by non-steroidal anti-inflammatory drugs (NSAIDs).
Zantac is in a class of drugs called H2 blockers, which block the production of acid in the stomach. It comes as a prescription and over-the-counter (OTC) product.
The Food and Drug Administration (FDA) first approved Zantac in 1984.
You and your doctor should monitor certain health issues. This can help make sure you stay safe while you take this drug. These issues can include your kidney function. Your doctor may do blood tests to check how well your kidneys are working. If your kidneys aren’t working well, your doctor may lower your dosage of this drug.
There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.
Antac oral tablet comes with several warnings.
Warnings for people with certain health conditions
For people with kidney problems: If you have kidney problems or a history of kidney disease, you may not be able to clear this drug from your body well. This may increase the levels of Antac in your body and cause more side effects.
For people with liver problems: If you have liver problems or a history of liver disease, you may not be able to process this drug well. This may increase the levels of Antac in your body and cause more side effects.
For people with acute porphyria (an inherited blood disorder): You shouldn’t use this drug if you have a history of an acute porphyria attack. This drug can trigger an acute porphyric attack.
For people with gastric cancer: This drug reduces the amount of acid in your stomach. This can help improve the symptoms of your gastrointestinal condition. However, if your symptoms are caused by a cancerous gastric tumor, you may still have the tumor. This drug does not treat cancer.
Warnings for other groups
For pregnant women: Research in animals has not shown that this drug poses a risk to a pregnancy. However, animal studies do not always predict the way humans would respond. And there aren’t enough studies of this drug in pregnant humans to see if it is harmful.
That said, this drug should only be used in pregnancy if clearly needed. Call your doctor right away if you become pregnant while taking this drug.
For women who breastfeeding: You should tell your doctor before taking this drug. Antac may pass into breast milk and cause side effects in a child who is breastfed. You may need to ask your doctor to help you weigh the benefits of breastfeeding versus taking this drug.
For seniors: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects. In rare cases, this drug may cause confusion, agitation, depression, and hallucinations. These problems happen most often in seniors who are very ill.
For children: Antac has not been confirmed as safe and effective in children younger than 1 month for any condition. Antac has not been confirmed as safe and effective in people younger than 18 years for conditions where the stomach makes too much acid. These conditions include Zollinger-Ellison syndrome.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
Drugs you should not use with Antac
Delavirdine: Do not take delavirdine with Antac. Doing so can cause dangerous effects. Antac reduces the levels of delavirdine in your body. This means delavirdine won’t work as well.
1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
2. "Product Information. Zantac 75 (Antac)." Pfizer U.S. Pharmaceuticals, New York, NY.
3. Cerner Multum, Inc. "Australian Product Information." O 0
4. "Product Information. Zantac (Antac)." Glaxo Wellcome, Research Triangle Park, NC.
Q: My husband is on Antac 150 mg, 2 a day. What kind of diet should he eat?
A: Antac (brand name Zantac) can generally be administered without regard to food and has no particular food requirements. However, patients should avoid alcohol, which can increase the risk of stomach damage. For patients with either ulcers or reflux (GERD), some foods may bother them more than others, so avoiding those items is recommended. For more specific information, consult your physician or health care provider. You may also find helpful information about foods and cooking for patients with ulcers and reflux at //www.everydayhealth.com/digestive-health/experts-what-causes-ulcers.aspx and //www.everydayhealth.com/gerd/guide/
Where can I get more information?
Your pharmacist can provide more information about Antac.
What is Antac, and how does it work (mechanism of action)?
Antac is an oral drug that blocks the production of acid by acid-producing cells in the stomach. It belongs to a class of drugs called H2 (histamine-2) blockers that also includes cimetidine (Tagamet), nizatidine (Axid), and famotidine (Pepcid). Histamine is a naturally occurring chemical that stimulates cells in the stomach (parietal cells) to produce acid. H2-blockers inhibit the action of histamine on the cells, thus reducing the production of acid by the stomach. Since excessive stomach acid can damage the esophagus, stomach, and duodenum and lead to inflammation and ulceration, reducing stomach acid prevents and heals acid-induced inflammation and ulcers. The FDA approved Antac in October 1984.
Antac side effects
Stop using this medicine and get emergency medical help if you have any of these signs of an allergic reaction to Antac: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medicine and call your doctor at once if you have a serious side effect such as:
stomach pain, loss of appetite;
dark urine, jaundice (yellowing of the skin or eyes);
fever, chills, cough with mucus, chest pain, feeling short of breath;
fast or slow heart rate;
easy bruising or bleeding; or
problems with your skin or hair.
Common Antac side effects may include:
headache (may be severe);
sleep problems (insomnia);
decreased sex drive, impotence, or difficulty having an orgasm; or
swollen or tender breasts (in men);
nausea, vomiting, stomach pain; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
3. Who can and can't take ranit >
Antac can be taken by adults. It can also be given to children under 16 years of age on prescription.
Antac isn't suitable for some people. To make sure that it is safe for you, tell your doctor if you:
- have had an allergic reaction to Antac or any other medicines in the past
- have kidney problems
- have an intolerance to, or cannot absorb, some sugars such as fructose
- have been advised to eat a low calcium or low salt diet
- cannot have alcohol - Antac liquid contains a small amount of alcohol
- have phenylketonuria, a rare inherited illness
If you're due to have an endoscopy to find out what's causing your symptoms, stop taking Antac at least 2 weeks before your procedure. This is because Antac may hide some of the problems that would usually be spotted during an endoscopy.
How to take it
You can take Antac with or without food. However, if you get symptoms whenever you eat or drink, take your medicine 30 minutes to 60 minutes before having a drink, snack or meal.
Tablets - swallow tablets whole with a glass of water, milk or juice.
Soluble tablets - dissolve tablets in half a glass of water. Do not use milk, fizzy water or other fizzy drinks. Wait until the medicine has completely dissolved and then drink it straight away.
Liquid - this comes with a syringe or spoon to help you measure it. If you don't have a syringe or spoon, ask your pharmacist for one. Do not use a kitchen teaspoon as it won't give you the right amount.
Liquid Antac is suitable for children and people who find it difficult to swallow tablets.