Anistal syrup


  • Active Ingredient: Ranitidine
  • 300 mg, 150 mg
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What is Anistal?

The active ingredient of Anistal brand is ranitidine. Ranitidine is in a group of drugs called histamine-2 blockers. Ranitidine works by reducing the amount of acid your stomach produces. The empirical formula is C13H22N4O3S.HCl, representing a molecular weight of 350.87. Ranitidine HCl USP is a white to pale yellow crystalline powder that is soluble in water. It has a slightly bitter taste and sulfur-like odor. Each Ranitidine tablets, USP 150 mg for oral administration contains 168 mg of Ranitidine HCl USP equivalent to 150 mg of Ranitidine. Each tablet also contains the inactive ingredients magnesium stearate, microcrystalline cellulose, croscarmellose sodium, silicon dioxide, hypromellose, titanium dioxide, triacetin, and iron oxide red. Each Ranitidine tablets, USP 300 mg for oral administration contains 336 mg of Ranitidine HCl USP equivalent to 300 mg of Ranitidine. Each tablet also contains the inactive ingredients magnesium stearate, microcrystalline cellulose, croscarmellose sodium, silicon dioxide, hypromellose, titanium dioxide, triacetin, and iron oxide red.

Used for

Anistal is used to treat diseases such as: Cutaneous Mastocytosis, Duodenal Ulcer, Duodenal Ulcer Prophylaxis, Eczema, Erosive Esophagitis, Gastric Ulcer Maintenance Treatment, Gastrointestinal Hemorrhage, GERD, Indigestion, Pathological Hypersecretory Conditions, Stomach Ulcer, Stress Ulcer Prophylaxis, Surgical Prophylaxis, Urticaria, Zollinger-Ellison Syndrome.

Side Effect

Possible side effects of Anistal include: ; ; ; ; ; .

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How should I take Anistal?

Take exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.

Do not crush, chew, or break the Anistal effervescent tablet, and do not allow it to dissolve on your tongue. The 25-milligram effervescent tablet must be dissolved in at least 1 teaspoon of water before swallowing. The150-milligram effervescent tablet should be dissolved in 6 to 8 ounces of water.

Allow the Anistal effervescent tablet to dissolve completely in the water, and then drink the entire mixture. If you are giving this medicine to a child, you may draw the liquid mixture into a medicine dropper and empty the dropper into the child's mouth.

Anistal granules should be mixed with 6 to 8 ounces of water before drinking.

Measure Anistal liquid with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

It may take up to 8 weeks before your ulcer heals. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 6 weeks of treatment.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Anistal.

Store at room temperature away from moisture, heat, and light.

Q. How long has NDMA been present in Anistal?

A. FDA does not have enough scientific evidence yet to determine how long NDMA has been present in Anistal. The agency is continuing to investigate and will communicate more information as it is available.


GENERIC NAME(S): Anistal Hcl

Anistal is used to treat ulcers of the stomach and intestines and prevent them from coming back after they have healed. This medication is also used to treat certain stomach and throat (esophagus) problems (such as erosive esophagitis, gastroesophageal reflux disease-GERD, Zollinger-Ellison syndrome). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as cough that doesn't go away, stomach pain, heartburn, and difficulty swallowing. Anistal belongs to a class of drugs known as H2 blockers.

How it works

Anistal belongs to a class of drugs called histamine receptor antagonists. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Anistal works by reducing the amount of acid in your stomach.

Is Anistal considered an antacid?

No. Anistal works by reducing the amount of acid your stomach makes. Antacids, on the other hand, neutralize the acid that your stomach has already made.

The Healthline Medical Team Answers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

Anistal oral tablet may cause drowsiness as well as other side effects.

Q: I have COPD and was told to take two 75 mg Zantac at bedtime. Also, I am to take Vytorin. Should these be taken together?

A: It is very important for patients to be aware of possible drug interactions when taking multiple medications. According to the prescribing information available for Vytorin, no documented drug interaction exists with Zantac (Anistal). For additional information regarding Zantac (Anistal) or Vytorin: // // Beth Isaac, PharmD

Interactions that can make your drugs less effective

When certain drugs are used with Anistal, they may not work as well. This is because the amount of these drugs in your body may be decreased. Examples of these drugs include:

  • Atazanavir: If you need to take these drugs together, your doctor will tell you how long you should wait between doses of these medications.
  • Gefitinib: If you take gefitinib and Anistal with the antacid sodium bicarbonate, gefitinib may not work as well. Talk to your doctor if you’re taking gefitinib and Anistal.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • the severity of your condition
  • other medical conditions you have
  • how you react to the first dose

For the Consumer

Applies to Anistal: oral solution, oral tablets and tablets for, oral tablets effervescent for solution, parenteral injection, parenteral injection for iv infusion only

Side effects include:

Oral or parenteral therapy: Headache, sometimes severe.

IM therapy: Transient pain at injection site.

IV therapy: Transient local burning or itching.

What other drugs will affect Anistal?

Before taking Anistal, tell your doctor if you are taking triazolam (Halcion). You may not be able to use this medicine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs that can interact with Anistal. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

What are the side effects of Anistal?

Minor side effects occur and these are:

Other important, but rare, side effects include:

8. Cautions with other medicines

Some medicines can interfere with Anistal and make you more likely to have side effects.

Tell your doctor if you're taking these medicines before you start taking Anistal:

  • anti-fungal medicines such as itraconazole, ketoconazole or posaconazole
  • any medicine used to treat cancer
  • HIV medicines

These are not all the medicines that may not mix well with Anistal. For a full list see the leaflet inside your medicines packet.

How to use Anistal Hcl

Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. It may be prescribed 4 times a day for some conditions. If you are taking this medication once daily, it is usually taken after the evening meal or before bedtime.

Measure the dose carefully using a measuring spoon or a special medication spoon available from your pharmacist. Do not use household spoons or you may not get the correct dose.

The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage may also be based on body weight. Follow your doctor's instructions carefully. You may take other medications (e.g., antacids) for your condition as recommended by your doctor.

Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day. Do not increase your dose or take it more often than prescribed. Do not stop taking this without your doctor's approval because this may delay healing of the ulcer.

Tell your doctor if your condition does not improve or if it worsens.

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