What should I discuss with my healthcare provider before taking Alfate (Carafate)?
You should not use Alfate if you are allergic to it.
Tell your doctor if you have ever had:
Tell your doctor if you are pregnant or breastfeeding.
Alfate is not approved for use by anyone younger than 18 years old.
Where can I get more information:
Your pharmacist has additional information about Alfate written for health professionals that you may read.
Call your veterinarian for medical advice about any side effects to your pet. You may report side effects to the FDA at 1-800-FDA-1088.
What is the most important information I should know about Alfate:
Alfate is a prescription medication not FDA approved for veterinary use; however, it is a commonly accepted practice for veterinarians to use this medication in dogs, cats, and horses. Alfate is available as 1 Gm tablets. The usual dose for dogs is 1/2 to 1 tablet by mouth 3 times a day. For cats, the usual dose is 1/4 to 1/2 tablet by mouth every 8 to 12 hours. For horses, the usual dose is 4.5 mg to 9 mg per pound 4 times a day.
In a multicenter, double-blind, placebo-controlled study of CARAFATE Oral Suspension, a dosage regimen of 1 gram (10 mL) four times daily was demonstrated to be superior to placebo in ulcer healing.
Results From Clinical Trials Healing Rates for Acute Duodenal Ulcer
Equivalence of Alfate oral suspension to Alfate tablets has not been demonstrated.
What other drugs will affect Alfate?
Other drugs may affect Alfate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Pregnancy Category B.
Teratogenicity studies have been performed in mice, rats, and rabbits at doses up to 50 times the human dose and have revealed no evidence of harm to the fetus due to Alfate. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
What is Alfate (Carafate)?
Alfate is used short-term (up to 8 weeks) to treat an active duodenal ulcer.
Alfate works mainly in the lining of the stomach and is not highly absorbed into the body. This medicine adheres to ulcer sites and protects them from acids, enzymes, and bile salts.
Alfate can heal an active ulcer, but it will not prevent future ulcers from occurring.
Alfate may also be used for purposes not listed in this medication guide.
How should this medicine be used?
Alfate comes as a tablet and liquid to take by mouth. If you are taking Alfate to treat ulcers, the tablets or liquid usually are taken four times a day. If you are taking Alfate to prevent an ulcer from returning after it has healed), the tablets usually are taken twice a day. Take Alfate on an empty stomach, 2 hours after or 1 hour before meals. Take Alfate around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Alfate exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Shake the liquid well before each use to mix the medication evenly.
This medicine must be taken regularly to be effective. It may take up to 8 weeks for ulcers to heal.
Carafate (Alfate) is a medication prescribed for the treatment of peptic ulcer disease and prevent recurrent ulcers, prevent ulcers caused by NSAIDs, and the treatment of GERD. Side effects include:
Drug interactions, warnings and precautions, and pregnancy and breastfeeding safety should be reviewed prior to taking this medication.