Sortiva tablets


  • Active Ingredient: Losartan
  • 50 mg, 25 mg
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What is Sortiva?

The active ingredient of Sortiva brand is losartan. Losartan is an angiotensin II receptor antagonist. Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. C22H22ClKN6O M.W. 461.01 Losartan potassium, USP is a white to off-white free-flowing crystalline powder. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of Losartan. Losartan potassium tablets USP are available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of Losartan potassium, USP and the following inactive ingredients: D&C Yellow #10 aluminum lake, FD&C Blue #2/indigo carmine aluminum lake, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, pregelatinized starch, talc, and titanium dioxide. Additionally, 50 mg and 100 mg tablets contain FD&C Yellow #6/sunset yellow FCF aluminum lake. Losartan potassium tablets USP, 25 mg, 50 mg and 100 mg contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively.

Used for

Sortiva is used to treat diseases such as: Alport Syndrome, Diabetic Kidney Disease, High Blood Pressure.

Side Effect

Possible side effects of Sortiva include: depression; itching; confusion; fainting; indigestion.

How to Buy Sortiva tablets online?

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Diuretics (water pills)

Sortiva can cause low blood pressure. Your risk of low blood pressure is increased if you also take diuretics. Symptoms of low blood pressure can include dizziness or feeling faint, or chest pain. Examples of diuretics include:

  • hydrochlorothiazide
  • furosemide
  • spironolactone

Serious side effects

It happens rarely, but some people have serious side effects after taking Sortiva.

Call a doctor straight away if you have:

  • yellow skin or the whites of your eyes turn yellow - this can be a sign of liver problems
  • severe stomach pain - this can be a sign of an inflamed pancreas
  • pale skin, feeling tired, faint or dizzy, purple spots, any sign of bleeding, sore throat and fever - these can be signs of blood or bone marrow disorder
  • weakness, an irregular heartbeat, pins and needles and muscle cramps - these can be signs of changes in the sodium and potassium levels in your blood

Before taking Sortiva,

  • tell your doctor and pharmacist if you are allergic to Sortiva, any other medications, or any of the ingredients in Sortiva tablets. Ask your pharmacist for a list of the ingredients.
  • tell your doctor if you have diabetes (high blood sugar) and you are taking aliskiren (Tekturna, in Amturnide, Tekamlo, Tekturna HCT). Your doctor will probably tell you not to take Sortiva if you have diabetes and you are also taking aliskiren.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril (Capoten, in Capozide), enalapril (Vasotec), fosinopril, lisinopril (in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), and selective COX-2 inhibitors such as celecoxib (Celebrex); diuretics ('water pills') including potassium-sparing diuretics such as amiloride (Midamor), spironolactone (Aldactone, in Aldactazide), and triamterene (Dyrenium, in Dyazide, in Maxzide); fluconazole (Diflucan); lithium ( Lithobid); phenobarbital; potassium supplements; and rifampin (Rifadin, Rimactane, in Rifamate, in Rifater). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had heart failure or kidney or liver disease.
  • tell your doctor if you are breastfeeding.
  • you should know that Sortiva may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking Sortiva. To help avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
  • you should know that diarrhea, vomiting, not drinking enough fluids, and sweating a lot can cause a drop in blood pressure, which may cause lightheadedness and fainting. Tell your doctor if you have any of these problems or develop them during your treatment.

Drug interaction overview

  • Coadministration with other drugs that raise serum potassium levels may result in hyperkalemia
  • Increases in serum lithium concentrations and toxicities have been reported during coadministration of lithium with angiotensin II receptor antagonists; monitor serum lithium levels during concomitant use
  • Coadministration of NSAIDs, including selective COX-2 inhibitors, with angiotensin II receptor antagonists (including Sortiva) in patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function may result in deterioration of renal function, including possible acute renal failure; these effects are usually reversible
  • Do not coadminister aliskiren with Sortiva in patients with diabetes; avoid use of aliskiren with Sortiva in patients with renal impairment (GFR Formulary Patient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Adding plans allows you to:

  • View the formulary and any restrictions for each plan.
  • Manage and view all your plans together – even plans in different states.
  • Compare formulary status to other drugs in the same class.
  • Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.


  • Store Sortiva at room temperature between 59°F and 86°F (15°C and 30°C).
  • Don’t freeze this drug.
  • Keep this medication away from light.
  • Don’t store this medication in moist or damp areas, such as bathrooms.

Is Sortiva safe to take if I'm pregnant or breastfeeding?

When used in the second or third trimester of pregnancy , ARBs can cause injury and even death to the fetus. Sortiva should not be used during pregnancy. When pregnancy is first detected, Sortiva should be stopped.

It is not known whether Sortiva is excreted in breast milk, but Sortiva and its active form are excreted in rat milk. Due to the possibility of harm to the nursing infant, if possible, Sortiva should be discontinued by females who are nursing.

Drug allergies

People who are allergic to Sortiva potassium or other inactive ingredients in the drug should avoid it. Inactive ingredients in Cozaar are:

  • hydroxypropyl cellulose
  • hypromellose
  • anhydrous lactose
  • magnesium stearate
  • microcrystalline cellulose
  • cornstarch
  • titanium dioxide

Inform a doctor or pharmacist of all drug allergies before taking Sortiva.

Can Sortiva cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with Sortiva. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Rated Sortiva (Cozaar) for Diabetic Nephropathy Report

I want to thanks everyone who wrote the reviews. I was on Sortiva for 2 weeks and had such bad side effects. I'm so happy to see these posts. I've been on Sortiva 25mg for about 2 weeks. At first it was ok, a few weird palpitations, but I ignored them. The last week I have had shoulder pain and back pain that is horrible, worse heartburn that I’ve never had in my life, nausea, stingy eyes, and chest pain. It's horrible. My blood pressure is higher due to all the pain I experienced. The pain has left me miserable. I stopped taking Sortiva three days ago and feel much better. Seeing the doctor in 2 weeks. This drug is dangerous!

6. How to cope with s >

What to do about:

  • feeling dizzy - if Sortiva makes you feel dizzy when you stand up, try getting up very slowly or stay sitting down until you feel better. If you begin to feel dizzy, lie down so that you don't faint, then sit until you feel better. Do not drive or use tools or machines if you feel dizzy, have muscle cramps or muscle pain, or if you just feel a bit shaky.
  • headaches - make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller. Headaches should usually go away after the first week of taking Sortiva. Talk to your doctor if they last longer than a week or are severe.
  • feeling sick (nausea) - try taking your tablets with or after a meal or snack. It may also help if you don't eat rich or spicy food.
  • being sick (vomiting) or diarrhoea - drink plenty of fluids, such as water or squash, to prevent dehydration - if you're being sick, take small, frequent sips. Speak to a pharmacist if you have signs of dehydration, such as peeing less than usual or having dark, strong-smelling pee. If you get severe diarrhoea or vomiting from a stomach bug or illness, tell your doctor. You may need to stop taking Sortiva for a while until you feel better.
  • pain in your joints or muscles - if you get unusual muscle pain, weakness or tiredness which isn't from exercise or hard work, talk to your doctor. You may need a blood test to check what might be causing it.

Was your medicine recalled?

Here are the doses, lot numbers and expiration dates of the recalled medicine:

Sortiva Potassium Tablets 50 mg:

  • BLl711A, BLl710A, November 2019

Sortiva Potassium and Hydrochlorothiazide Tablets 50 mg/ 12.5 mg:

  • BLK719A, BLK720A, BLK721A, BLK722A, BLK723A, BLK724A, September 2019
  • BLK725A, BLK726A, October 2019
  • BLK804A, BLK806A, January 2020
  • BLK825A, BLK826A, October 2021

Sortiva Potassium and Hydrochlorothiazide Tablets 100 mg/ 12.5 mg:

  • BLM716A, BLM717A, July 2019
  • BLM719A, BLM720A, August 2019
  • BLM721A, BLM722A, September 2019
  • BLM723A, BLM724A, BLM725A, October 2019
  • BLM726A, November 2019
  • BLM802A, BLM803A, December 2019
  • BLM825A, BLM826A, BLM827A, September 2021

Contributing: Ken Alltucker

Follow Kelly Tyko on Twitter: @KellyTyko

Sortiva Interactions

Tell your doctor about any allergies you have, and about all the medications you take, whether prescription or over-the-counter, vitamins, illegal or recreational drugs, and dietary or herbal supplements, as they can affect how Sortiva works.

If you have diabetes or kidney disease, avoid using Sortiva together with medications containing aliskiren (Amturnide, Tekturna, Tekamio, Valturna).

Consult your doctor if you take the following medication:

  • Aspirin (Anacin, Bayer, or Bufferin)
  • Ibuprofen (Advil)
  • Naproxen (Aflaxen, Aleve)
  • Potassium-sparing diuretics (Amilor >Back to Top

Getting the most from your treatment

  • Try to keep your regular appointments with your doctor. This is so your progress can be monitored. Your doctor may want you to have some blood tests from time to time to check on your kidneys, and also how much potassium is in your blood.
  • If you buy any medicines, check with a pharmacist that they are suitable to take with Sortiva. This is because some anti-inflammatory painkillers (such as aspirin and ibuprofen) can interfere with the way it works, and also may increase the risk of side-effects.
  • It is very important that you follow any dietary and lifestyle advice that you have been given by your doctor, such as eating a healthy diet, not smoking, and taking regular exercise.
  • If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on Sortiva because it will increase the risk of side-effects, such as feeling dizzy or faint.
  • Try to avoid salt substitutes which contain potassium. This is because the substitutes will increase the amount of potassium in your blood and this can cause problems.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking Sortiva. This is because your blood pressure may drop too low if you are given some anaesthetics.
  • Treatment with Sortiva is usually long-term unless you experience an adverse effect. Continue to take the tablets regularly, unless you are advised otherwise by your doctor.

If you are also taking hydrochlorothiazide in combination with this medicine

  • Studies have suggested that taking higher doses of hydrochlorothiazide for long periods of time may increase the risk of certain skin cancers.
  • Tell your doctor if you have ever been treated for skin cancer before.
  • Tell your doctor about any new or changed moles or worrying marks on your skin.
  • Use a sunscreen in strong sunlight. Do not use sunbeds.

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