Sedeten tablets


  • Active Ingredient: Losartan
  • 50 mg, 25 mg
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What is Sedeten?

The active ingredient of Sedeten brand is losartan. Losartan is an angiotensin II receptor antagonist. Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. C22H22ClKN6O M.W. 461.01 Losartan potassium, USP is a white to off-white free-flowing crystalline powder. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of Losartan. Losartan potassium tablets USP are available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of Losartan potassium, USP and the following inactive ingredients: D&C Yellow #10 aluminum lake, FD&C Blue #2/indigo carmine aluminum lake, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, pregelatinized starch, talc, and titanium dioxide. Additionally, 50 mg and 100 mg tablets contain FD&C Yellow #6/sunset yellow FCF aluminum lake. Losartan potassium tablets USP, 25 mg, 50 mg and 100 mg contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively.

Used for

Sedeten is used to treat diseases such as: Alport Syndrome, Diabetic Kidney Disease, High Blood Pressure.

Side Effect

Possible side effects of Sedeten include: fast, irregular, pounding, or racing heartbeat or pulse; nightmares; weight gain; Abdominal or stomach pain; sneezing.

How to Buy Sedeten tablets online?

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Serious allergic reaction

In rare cases, Sedeten may cause a serious allergic reaction (anaphylaxis).

Q: My husband is taking Sedeten for high blood pressure. Can he drink wine or vodka?

A: Generally speaking, drug interactions fall into three main categories: Drug-drug (i.e., prescription, over-the-counter, herbals, dietary supplements) interactions occur when two or more drugs react with each other. Drug-diet (food/drink) interactions result from drugs reacting with foods or drinks. Drug-disease interactions may occur when an existing medical condition makes certain drugs potentially harmful. A review of the prescribing information for Sedeten does not specifically cite a drug interaction with alcohol and Sedeten (Cozaar), an angiotensin reuptake inhibitor prescribed for hypertension. However, alcohol can increase the side effects of Sedeten. The common side effects with Sedeten are dizziness, headache, insomnia, muscle pain, cough, fatigue, orthostatic hypotension, and hypotension. Alcohol can cause dehydration and increase the risk for orthostatic hypotension which is a sudden drop in blood pressure upon arising from a sitting position. Symptoms of orthostatic hypotension include dizziness, lightheadedness, and fainting. The extent of orthostatic hypotension will vary between individuals and depends on other prescription medications, non-prescription medications, dietary supplements, nutritional supplements and current medical conditions. This is not a complete list of side effects for Sedeten. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Consuelo Worley, RPh

Getting the most from your treatment

  • Try to keep your regular appointments with your doctor. This is so your progress can be monitored. Your doctor may want you to have some blood tests from time to time to check on your kidneys, and also how much potassium is in your blood.
  • If you buy any medicines, check with a pharmacist that they are suitable to take with Sedeten. This is because some anti-inflammatory painkillers (such as aspirin and ibuprofen) can interfere with the way it works, and also may increase the risk of side-effects.
  • It is very important that you follow any dietary and lifestyle advice that you have been given by your doctor, such as eating a healthy diet, not smoking, and taking regular exercise.
  • If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on Sedeten because it will increase the risk of side-effects, such as feeling dizzy or faint.
  • Try to avoid salt substitutes which contain potassium. This is because the substitutes will increase the amount of potassium in your blood and this can cause problems.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking Sedeten. This is because your blood pressure may drop too low if you are given some anaesthetics.
  • Treatment with Sedeten is usually long-term unless you experience an adverse effect. Continue to take the tablets regularly, unless you are advised otherwise by your doctor.

If you are also taking hydrochlorothiazide in combination with this medicine

  • Studies have suggested that taking higher doses of hydrochlorothiazide for long periods of time may increase the risk of certain skin cancers.
  • Tell your doctor if you have ever been treated for skin cancer before.
  • Tell your doctor about any new or changed moles or worrying marks on your skin.
  • Use a sunscreen in strong sunlight. Do not use sunbeds.

How much will I take?

The dose of Sedeten you take depends on why you need the medicine. Take it as instructed by your doctor.

Usually, adults take:

  • 50mg to 100mg once a day to treat high blood pressure and to protect their kidneys
  • 12.5mg to 150mg once a day for heart failure

The dose may be lower if you've recently lost body fluids (for example, because of diarrhoea or being sick) or you're over the age of 75.

If your child needs Sedeten, your doctor will usually use your child's weight to work out the right dose.

What Are Warnings and Precautions for Sedeten?

  • Discontinue as soon as possible when pregnancy is detected; drug affects renin-angiotensin system, causing oligohydramnios, which may result in fetal injury or death
  • This medication contains Sedeten. Do not take Cozaar if you are allergic to Sedeten or any ingredients contained in this drug
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately

  • Hypersensitivity
  • Coadministration with aliskiren in patients with diabetes mellitus

Effects of Drug Abuse

  • Increases risks of low blood pressure and abnormal potassium levels in the blood
  • See also "What Are Side Effects Associated with Using Sedeten?”

  • See also "What Are Side Effects Associated with Using Sedeten?”

  • Rapid swelling, volume-depletion, severe congestive heart failure, hepatic or renal impairment
  • Correct volume or salt depletion prior to administration
  • Increases risks of low blood pressure and abnormal potassium levels in the blood
  • Monitor renal function and potassium levels in susceptible patients
  • Discontinue immediately if patient is pregnant; potential risk of congenital malformations
  • Use with caution in renal artery stenosis, and avoid in bilateral renal arterystenosis
  • Renal impairment reported
  • Increased heart failure-related morbidity in patients receiving angiotensin converting enzyme inhibitors (ACE inhibitors) and beta-blockers concomitantly; such combination therapy is not recommended
  • Dual blockade of the renin-angiotensin-aldosterone system (an angiotensin-receptor blocker plus an ACE inhibitor) in patients with established atheroscleroticdisease, heart failure, or diabetes with end-organ damage is associated with a higher frequency of low blood pressure, fainting, abnormal potassium levels, and altered renal function (including acute renal failure) in comparison with use of a single renin-angiotensin-aldosterone system agent; limit dual blockade to individually defined cases with close monitoring of renal function; closely monitor blood pressure
  • Risk of severe allergic reactions or rapid swelling

Pregnancy and Lactation with Sedeten

  • Use Sedeten in LIFE-THREATNING emergencies when no safer drug is available. There is positive evidence of human fetal risk
  • Use of Sedeten or other drugs that act on the renin-angiotensin system during the 2nd and 3rd trimesters of pregnancy reduces renal function and increases fetal and neonatal morbidity and death. Resulting levels of low amniotic fluid can be associated with fetal lung underdevelopment and skeletal deformations. Potential neonatal adverse effects include skull underdevelopment, failure of the kidneys to produce urine, low blood pressure, kidney failure, and death
  • When pregnancy is detected, discontinue of Sedeten as soon as possible
  • It is unknown if Sedeten is excreted in milk; therefore use of Sedeten is not recommended when lactating. Consult with a physician

Rated Sedeten (Cozaar) for Hypertension Report

I'm a 48 year old male and I've been on Micardis 80mg for about 10 years. Micardis is the perfect BP med for me. 3 weeks ago the Kroger Pharmacy that fills my meds was out of Micardis so my Doc prescribed me Sedeten 50mg. Within two or three days I started throwing up and the worst nausea ever. I missed four days of work because I could not stop dry heaving. About a week in I started having a pain just to the right of my navel and then my lower right stomach started killing. I went back to my Doc thinking I had Appendicitis and with all the symptoms i was having she thought Appendicitis also. She scheduled me for a CAT scan (I have no insurance) I was putting off the scan until the pain just got unbearable. Then my feet and lower back started to hurt. I Google Sedeten and it brought me to this page. I now see that Sedeten is probably the culprit. It’s been 24 hours since the last pill and all the symptoms are still there but seen to be a little better. I will update in a week. They should take Sedeten off the market.

Allergy warning

Sedeten can cause a severe allergic reaction. Symptoms include:

  • trouble breathing
  • swelling of your throat or tongue
  • hives

If you develop these symptoms, call 911 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

What Is Sedeten and How Does It Work?

Sedeten is used to treat high blood pressure and to help protect the kidneys from damage due to diabetes. It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Sedeten belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily.

Sedeten is available under the following different brand names: Cozaar.

Dosages of Sedeten

Adult and pediatric dosages

Dosage Considerations -- Should Be Given As Follows:

Adult dosage considerations

  • 50 mg/day orally (25 mg/day in patients with possible intravascular depletion or receiving diuretics)
  • Dosage range: 25-100 mg/day orally in 1 or 2 daily doses

  • 50 mg orally once/day initially; may increase to 100 mg orally once/day; may use in combination with a thiazide diuretic

  • Generally, adjust dosage monthly; adjust more aggressively in high-risk patients

Pediatric dosage considerations

Under 6 years of age:

  • Safety and efficacy not established

6 years and older:

  • 0.7 mg/kg per day (up to 50 mg/per day) orally initially, not to exceed 1.4 mg/kg per day (or 100 mg/day)
  • Oral suspension may be used

Diuretics (water pills)

Sedeten can cause low blood pressure. Your risk of low blood pressure is increased if you also take diuretics. Symptoms of low blood pressure can include dizziness or feeling faint, or chest pain. Examples of diuretics include:

  • hydrochlorothiazide
  • furosemide
  • spironolactone

What are the uses for Sedeten?

Sedeten is used for treating hypertension, reducing the risk of stroke in patients with hypertension, and left ventricular hypertrophy (over developed heart muscle), and treating people with type 2 diabetes, and hypertensive patients with diabetic nephropathy (kidney disease). Sedeten may be used alone or in combination with other drugs.

Rated Sedeten (Cozaar) for Diabetic Nephropathy Report

I want to thank people for writing there reviews. I have been taking it about a week. I so sick an bad back pain. I will never take it again. I stopped taking it 2 days ago an feel much better. Thanks.

Rated Sedeten (Cozaar) for Hypertension Report

I've been taking losarten after Dr took me off of valsarten 160 mg. Still am having anziety dizziness double vision almost. Hate this drug it's 100 mg and my bp is not that low 138/80 am you g to try to get a Dr to give me something else used to take benacar 40 mg before my heart stent was put in I did not have a heart attack just a blockage in LAD lower artery destending

Sedeten Interactions

Tell your doctor about any allergies you have, and about all the medications you take, whether prescription or over-the-counter, vitamins, illegal or recreational drugs, and dietary or herbal supplements, as they can affect how Sedeten works.

If you have diabetes or kidney disease, avoid using Sedeten together with medications containing aliskiren (Amturnide, Tekturna, Tekamio, Valturna).

Consult your doctor if you take the following medication:

  • Aspirin (Anacin, Bayer, or Bufferin)
  • Ibuprofen (Advil)
  • Naproxen (Aflaxen, Aleve)
  • Potassium-sparing diuretics (Amilor >Back to Top

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