Lospre tablets


  • Active Ingredient: Losartan
  • 50 mg, 25 mg
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What is Lospre?

The active ingredient of Lospre brand is losartan. Losartan is an angiotensin II receptor antagonist. Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. C22H22ClKN6O M.W. 461.01 Losartan potassium, USP is a white to off-white free-flowing crystalline powder. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of Losartan. Losartan potassium tablets USP are available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of Losartan potassium, USP and the following inactive ingredients: D&C Yellow #10 aluminum lake, FD&C Blue #2/indigo carmine aluminum lake, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, pregelatinized starch, talc, and titanium dioxide. Additionally, 50 mg and 100 mg tablets contain FD&C Yellow #6/sunset yellow FCF aluminum lake. Losartan potassium tablets USP, 25 mg, 50 mg and 100 mg contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively.

Used for

Lospre is used to treat diseases such as: Alport Syndrome, Diabetic Kidney Disease, High Blood Pressure.

Side Effect

Possible side effects of Lospre include: stomach discomfort or upset; difficulty with swallowing; fast heartbeat; yellow eyes and skin; trouble sleeping.

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Lospre side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Lospre: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

In extremely rare cases, Lospre can cause a condition that results in the breakdown of skeletal muscle tissue, leading to potential kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Call your doctor at once if you have:

a feeling that you might pass out;

pain or burning when you urinate;

pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;

wheezing, chest pain;

drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting;

swelling, weight gain, feeling short of breath, urinating less than usual or not at all; or

high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling).

Common Lospre side effects may include:

cold or flu symptoms such as stuffy nose, sneezing, sore throat, fever;

pain in your legs or back;

stomach pain, diarrhea;

tired feeling; or

sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Will my dose go up or down?

After a few weeks your doctor will check your blood pressure and ask you if you're getting any side effects. You may also have blood tests to check how well your kidneys are working and the amount of potassium in your blood. Your doctor will then decide whether to change your dose of Lospre.

If Lospre doesn't bring your blood pressure down, your doctor may want to increase the dose. If your blood pressure gets too low or you get side effects, your doctor may want to lower your dose.

Rated Lospre (Cozaar) for Diabetic Nephropathy Report

My husband died while on this drug. He experienced similar bad side effects as some on this forum. He was only 55 and had diabetes and high blood pressure. He died one hour after taking this medicine on 4-19-19 of this year on Good Friday. The death was put down as pulmonary cardiac arrest. I wish I had done an autopsy. I still have the pills that were taken off the market (only certain batches? why only certain ones I do not know). I cannot prove this was the cause but he had many of the bad side effects many have posted here.

Rated Lospre (Cozaar) for Diabetic Nephropathy Report

I dont like the way its making me feel. It gives me a bad heart burn. My stomach feels like its on fire.

Rated Lospre (Cozaar) for Hypertension Report

Please check out Lospre before going on this drug. I didn’t and I felt like I would die. I read the review you all took time to post. Thanks! After my doctor changed my PB med to Lospre and taking the Lospre 100 for 3 months with side affects increasing, nausea, diarrhea, headache, arms & shoulder pain, anxiety, no energy, no appetite, stuffy nose, and heaviness feeling in chest, & I couldn’t stay awake because of exhaustion. I did go to the doctor and she had me stop the drug. I feel great, but still have the pain in my shoulders & arms. Like so many of you I will walk & exercise to control BP

Lospre is an angiotensin receptor blocker. It is also called an angiotensin-II receptor antagonist, or an AIIRA. You will have been prescribed Lospre for one of the following reasons:

Drugs or supplements that contain potassium

Lospre can increase the levels of a substance called potassium in your blood. Taking Lospre with drugs that contain potassium, potassium supplements, or salt substitutes with potassium, can increase your risk of hyperkalemia (high levels of potassium).

Examples of drugs that contain potassium include:

    Before taking this medicine

    You should not use Lospre if you are allergic to it.

    If you have diabetes, do not use Lospre together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna). You may also need to avoid taking this medicine with aliskiren if you have kidney disease.

    To make sure Lospre is safe for you, tell your doctor if you have:

    congestive heart failure;

    an electrolyte imbalance (such as low levels of potassium in your blood); or

    if you are dehydrated.

    FDA pregnancy category D. Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Lospre can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control.

    Lospre drug class

    Lospre belongs to a class of drugs called angiotensin receptor blockers (ARBs). A class of drugs is a group of medications that work in a similar way. They’re often used to treat similar conditions.

    Other ARBs include olmesartan, valsartan, and telmisartan. Like Lospre, these drugs can be used to treat high blood pressure.

    Drug forms and strengths

    Generic: Lospre

    • Form: oral tablet
    • Strengths: 25 mg, 50 mg, 100 mg

    Brand: Cozaar

    • Form: oral tablet
    • Strengths: 25 mg, 50 mg, 100 mg

    Lospre Dosage

    Lospre tablets are available in 25 mg, 50 mg, or 100 mg.

    The usual starting dose is 50 mg, but people treated with diuretics may be started off with 25 mg, once or twice daily.

    The effects are usually seen within a week, with maximal effect occurring between three to six weeks.

    For pediatric hypertensive patients older than 6, the recommended starting dose is 0.7 mg, once daily, up to 50 mg.

    Lospre may be taken with or without food.

    What are the uses for Lospre?

    Lospre is used for treating hypertension, reducing the risk of stroke in patients with hypertension, and left ventricular hypertrophy (over developed heart muscle), and treating people with type 2 diabetes, and hypertensive patients with diabetic nephropathy (kidney disease). Lospre may be used alone or in combination with other drugs.

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