Losartil tablets


  • Active Ingredient: Losartan
  • 50 mg, 25 mg
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What is Losartil?

The active ingredient of Losartil brand is losartan. Losartan is an angiotensin II receptor antagonist. Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. C22H22ClKN6O M.W. 461.01 Losartan potassium, USP is a white to off-white free-flowing crystalline powder. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of Losartan. Losartan potassium tablets USP are available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of Losartan potassium, USP and the following inactive ingredients: D&C Yellow #10 aluminum lake, FD&C Blue #2/indigo carmine aluminum lake, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, pregelatinized starch, talc, and titanium dioxide. Additionally, 50 mg and 100 mg tablets contain FD&C Yellow #6/sunset yellow FCF aluminum lake. Losartan potassium tablets USP, 25 mg, 50 mg and 100 mg contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively.

Used for

Losartil is used to treat diseases such as: Alport Syndrome, Diabetic Kidney Disease, High Blood Pressure.

Side Effect

Possible side effects of Losartil include: unusual tiredness or weakness; weakness in the arm or leg on one side of the body, sudden and severe; indigestion; slurred speech; yellow eyes and skin; muscle cramps or spasms.

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Rated Losartil (Cozaar) for Hypertension Report

Dr prescribed me 25mgs of this and I’ve been taking half that for 6 weeks. The first 5 weeks I was fine. No side effects. This last week has been hell. Back and knees are killing me. I’m soooo tired and dizzy. I can’t even function. I have an appt Friday and I have to drag myself in. I’m stopping them today. I feel awful. He shrugged it off as anxiety and not the meds. I feel awful!!

Which Losartil Pills were Recalled?

  • Losartil Potassium Hydrochlorothiazide
  • 100mg/25mg tablets in 1000-count plastic bottles
  • NDC 0781-5207-10
  • Lot number JB8912
  • Expiration date 06/2020

Before taking Losartil,

  • tell your doctor and pharmacist if you are allergic to Losartil, any other medications, or any of the ingredients in Losartil tablets. Ask your pharmacist for a list of the ingredients.
  • tell your doctor if you have diabetes (high blood sugar) and you are taking aliskiren (Tekturna, in Amturnide, Tekamlo, Tekturna HCT). Your doctor will probably tell you not to take Losartil if you have diabetes and you are also taking aliskiren.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin, in Lotrel), captopril (Capoten, in Capozide), enalapril (Vasotec), fosinopril, lisinopril (in Prinzide, in Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), and selective COX-2 inhibitors such as celecoxib (Celebrex); diuretics ('water pills') including potassium-sparing diuretics such as amiloride (Midamor), spironolactone (Aldactone, in Aldactazide), and triamterene (Dyrenium, in Dyazide, in Maxzide); fluconazole (Diflucan); lithium ( Lithobid); phenobarbital; potassium supplements; and rifampin (Rifadin, Rimactane, in Rifamate, in Rifater). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had heart failure or kidney or liver disease.
  • tell your doctor if you are breastfeeding.
  • you should know that Losartil may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking Losartil. To help avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
  • you should know that diarrhea, vomiting, not drinking enough fluids, and sweating a lot can cause a drop in blood pressure, which may cause lightheadedness and fainting. Tell your doctor if you have any of these problems or develop them during your treatment.

Allergy warning

Losartil can cause a severe allergic reaction. Symptoms include:

  • trouble breathing
  • swelling of your throat or tongue
  • hives

If you develop these symptoms, call 911 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

Michael Stewart, Reviewed by Sid Dajani | Last edited 25 Feb 2019 | Certified by The Information Standard

Take Losartil once each day. You can take your doses either before or after a meal.

Any side-effects are usually mild, and can include feeling dizzy or light-headed.

Some painkillers can interfere with Losartil and increase the risk of side-effects, so ask a pharmacist for advice before you buy any medicines 'over the counter'.

Clinical author's note: Michael Stewart 15/11/2018: Following an MHRA update, new advice has been added to this leaflet for people also taking the blood pressure medicine hydrochlorothiazide. Hydrochlorothiazide is only available in the UK in combination with other blood pressure medicines such as Losartil. It may be available on its own in other countries. For more information see 'Getting the most from your treatment' below or view the MHRA Alert.

Rated Losartil (Cozaar) for Hypertension Report

I have been on Losartil 100mg for about two years. It worked very well by lower the blood pressure plus no side effects. But recently it has caused side effects, my lower back is in horrific pain, and headaches. One natural food that will lower your blood pressure in 1/2 a hour, with no side effects is a whole ripe avocado, it is loaded with potassium. It works!

Rated Losartil (Cozaar) for Hypertension Report

I have been on Losartil for about 6 weeks and it started off fine but in the last 3 weeks I have felt really ill. I felt so tired all the time, my knees were so sore I could hardly walk, I had nausea, breathlessness, aches and pains in my arms and shoulders, bad heartburn and I put on half a stone. I could not stand it anymore and stopped taking it yesterday and after 24hrs I already feel better. My knees are not sore anymore and I can walk normally, I feel brighter and more energetic and don't feel ill. I will never take BP tablets again, they are pure poison. I will take mor exercise, check my diet. I also take crushed 4 cloves of garlic in honey every morning as that lowers your BP and drink Beetroot juice which is also good for BP. Don't take this medication.

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