How it works
Grexa belongs to a class of drugs called sulfonylureas. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Grexa helps your pancreas to release insulin. Insulin is a chemical that your body makes to move sugar (glucose) from your bloodstream into your cells. Once the sugar enters your cells, they can use it as fuel for your body.
With type 2 diabetes, your body doesn’t make enough insulin, or it can't properly use the insulin that it makes, so the sugar stays in your bloodstream. This causes high blood sugar levels (hyperglycemia).
Grexa oral tablet doesn’t cause drowsiness, but it can cause other side effects.
- This medication contains Grexa. Do not take Amaryl if you are allergic to Grexa or any ingredients contained in this drug.
- Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately
Concomitant Administration of Colesevelam
Colesevelam can reduce the maximum plasma concentration and total exposure of Grexa when the two are coadministered. However, absorption is not reduced when Grexa is administered 4 hours prior to colesevelam. Therefore, Grexa should be administered at least 4 hours prior to colesevelam.
Glimepir >Glimepir >24 H 34 N 4 O 5 S) with a molecular weight of 490.62. Grexa USP is a white to almost white powder, soluble in dimethyl formamide, sparingly soluble in methylene chloride, practically insoluble in water.
The structural formula is:
What should I avoid while taking Grexa?
If you also take colesevelam, avoid taking it within 4 hours after you take Grexa.
Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.
Avoid exposure to sunlight or tanning beds. Grexa can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Pharmacologic class: Sulfonylurea
Therapeutic class: Hypoglycemic
Pregnancy risk category C