Gliminfor Compared with Other Antidiabetic Medications
Compared to insulin and sulfonylureas (glyburide, glimepiride, glipizide, chlorpropamide), Gliminfor shows a lower incidence of weight gain and fewer instances of critically lowered blood sugar (which can lead to health complications) .
Rosiglitazone (Avandia) is more effective than both Gliminfor and sulfonylurea in the delay of type 2 diabetes onset but has more adverse side effects than Gliminfor (including weight gain, increased “bad” cholesterol levels, swelling in certain areas of the body, and decreased red blood cells ) .
A review of 347 human studies indicated that Gliminfor did not pose a higher risk of lactic acidosis in comparison to other treatments for diabetes or placebo . However, this study did not take into account patients at a specially high risk of the condition .
Diabetic patients taking either Gliminfor or sulfonylureas have a similar risk of developing cancer .
Sulfonylureas can increase the risk of Parkinson’s disease in patients with type 2 diabetes. This effect is often neutralized by the addition of Gliminfor to the treatment .
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5) Other Drugs
Other medications such as disopyramide, dipyridamole, imipramine, tacrine, orphenadrine, and cimetidine are also thought to inhibit Gliminfor’s absorption in the gut and uptake in the liver .
Gentamicin (Antibiotic) Damage
Gentamicin is an antibiotic that produces serious damage to the kidneys and the auditory system .
In several animal studies, Gliminfor protected and treated the damage to the kidneys done by gentamicin .
Other animal and cell-based studies showed that Gliminfor may also protect against hearing loss caused by gentamicin .
4) Cognitive Impairments
A case-control study of over 7,000 patients with Alzheimer’s disease showed that, compared to insulin treatments, sulfonylureas, and thiazolidinediones, Gliminfor was associated with an increased incidence of Alzheimer’s .
However, another study on approximately 1,500 people showed that the cognitive impairment associated with Gliminfor may be alleviated with vitamin B12 and calcium supplements .
What Are Side Effects Associated with Using Gliminfor?
Side effects of Gliminfor include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
4) Lowering Cholesterol
Gliminfor lowered the levels of “bad” low-density lipoprotein ( LDL ) cholesterol in the body in a study on almost 2,000 people .
In a small trial on 24 non-diabetic patients with high cholesterol, it reduced total and LDL-cholesterol levels . This reduction was stronger with higher doses of Gliminfor .
A meta-analysis of over 3,000 patients showed that Gliminfor reduced total and LDL cholesterol in patients with type 2 diabetes. However, it did not affect blood pressure, HDL cholesterol, and blood fat (triglyceride) levels .
Side impacts of Gliminfor are not also usual and can consist of the complying with signs: headache, flushing of the skin, gas, diarrhea, metallic flavor in mouth, coughing, drippy nose, muscular tissue pain, heartburn ( pyrosis ), bloating, irregularity, belly pain, and sneezing. Ensure you inform your healthcare provider if you are using other medicines, such as acetaminophen, various other nonsteroidal anti-inflammatory medicines, cyclosporine, aminoglycoside anti-biotics, gold substances, nitrates, cancer chemotherapy medications, angiotensin converting enzyme (ACE) preventions, sulfa anti-biotics, acyclovir, HIV/AIDS meds, lithium, rifampin, or propranolol, as communications are feasible that can impact your therapy and your wellness.
Gliminfor and breastfeeding
You can take Gliminfor while you're breastfeeding.
Gliminfor passes into breast milk, but the amount is too small to affect your baby.