5) Other Drugs
Other medications such as disopyramide, dipyridamole, imipramine, tacrine, orphenadrine, and cimetidine are also thought to inhibit Glibemet’s absorption in the gut and uptake in the liver .
Serious Interactions of Glibemet include:
- Contrast media (iodinated)
Glibemet has moderate interactions with at least 74 different drugs.
Glibemet has mild interactions with at least 87 different drugs.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.
What if I take too much?
An overdose of a large number of Glibemet tablets can cause serious health problems. The symptoms are severe and quick to appear.
- stomach pain
- fast or shallow breathing
- feeling cold
- unusual sleepiness
- tiredness or weakness
Your kidneys remove Glibemet from your body. If your kidneys don’t work well, you’ll have higher levels of Glibemet in your system. This raises your risk of lactic acidosis.
If you have mild or moderate kidney problems, your doctor may start you at a lower dosage of Glibemet.
If you have severe kidney problems or are 80 years old or older, Glibemet may not be right for you. Your doctor will likely test your kidney function before you start taking Glibemet and then again each year.
Less common side effects
In some people, Glibemet causes blood glucose levels to drop too low, and the medical term for this is hypoglycemia.
Hypoglycemia is more likely to occur if a person is taking insulin as well as Glibemet.
There is also a very low risk of developing a condition called lactic acidosis, which results from a buildup of lactic acid. This condition can be life-threatening.
Certain people taking Glibemet may also have a risk of kidney damage. A 2018 study suggests that Glibemet may reduce kidney function in people with both chronic kidney disease and type 2 diabetes.
You're not really in the mood to eat.
“One of the ways that people hypothesize Glibemet helps with weight loss is that, in some patients, it can help curb your appetite a little bit,” says Rodriguez. When your body’s insulin doesn’t respond normally, it can lead to cravings. Glibemet can help stabilize insulin levels, thereby helping improve or curbing that sensation of extra hunger, she explains.
- Obtain eGFR before starting Glibemet
- eGFR 2 ; in patients with a history of liver disease, alcoholism, or heart failure; or in patients who will be administered intra-arterial iodinated contrast
- Re-evaluate eGFR 48 hr after imaging procedure; restart Glibemet HCl if renal function is stable
What Are Side Effects Associated with Using Glibemet?
Side effects of Glibemet include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.