Amyx tablets

Amyx

  • Active Ingredient: Glimepiride
  • 4 mg, 2 mg, 1 mg
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What is Amyx?

The active ingredient of Amyx brand is glimepiride. Glimepiride is an oral diabetes medicine that helps control blood sugar levels. Glimepiride tablets contain the active ingredient Glimepiride and the following inactive ingredients:lactose monohydrate, magnesium stearate, microcrystalline cellulose, povidone, sodium lauryl sulfate and sodium starch glycolate (potato). In addition, the 2 mgand 4 mg tablets contain D&C Yellow No. 10 Aluminum Lake and the 4 mg also contains D&C Red No. 27 Aluminum Lake.

Used for

Amyx is used to treat diseases such as: Diabetes, Type 2.

Side Effect

Possible side effects of Amyx include: shakiness; bleeding gums; blood in the urine or stools; coma; blistering, peeling, or loosening of the skin; skin rash; cough or hoarseness; red skin lesions, often with a purple center.

How to Buy Amyx tablets online?

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There are no adequate and well-controlled studies of AMARYL in pregnant women. In animal studies there was no increase in congenital anomalies, but an increase in fetal deaths occurred in rats and rabbits at Amyx doses 50 times (rats) and 0.1 times (rabbits) the maximum recommended human dose (based on body surface area). This fetotoxicity, observed only at doses inducing maternal hypoglycemia, is believed to be directly related to the pharmacologic (hypoglycemic) action of Amyx and has been similarly noted with other sulfonylureas. AMARYL should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Because data suggest that abnormal blood glucose during pregnancy is associated with a higher incidence of congenital abnormalities, diabetes treatment during pregnancy should maintain blood glucose as close to normal as possible.

Adverse Reactions

The following serious adverse reactions are discussed in more detail below and elsewhere in the labeling:

  • Hypoglycemia
  • Hemolytic anemia

In clinical trials, the most common adverse reactions with Amyx were hypoglycemia, dizziness, asthenia, headache, and nausea.

Drugs that contain sulfonamides

These drugs can increase the effect of Amyx and cause low blood sugar. Examples of these drugs include:

  • sulfacetamide
  • sulfadiazine
  • sulfamethoxazole/trimethoprim (Bactrim)
  • sulfasalazine (Azulfidine)
  • sulfisoxazole

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

  • severe low blood sugar (less than 35 to 40 mg/dL). Symptoms may include:
    • mood changes, such as irritability, impatience, anger, stubbornness, or sadness
    • confusion, including delirium
    • lightheadedness or dizziness
    • sleepiness
    • blurred or impaired vision
    • tingling or numbness in your lips or tongue
    • headaches
    • weakness or fatigue
    • lack of coordination
    • nightmares or crying out in your sleep
    • seizures
    • unconsciousness
  • anaphylaxis. This is a severe and possibly a life-threatening allergic reaction. Symptoms may include trouble breathing, swelling of your throat or tongue, hives, or difficulty swallowing.
  • angioedema. This involves swelling of your skin, the layers under your skin, and your mucous membranes (ins >

    Amyx oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

    To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

    Examples of drugs that can cause interactions with Amyx are listed below.

    What happens if I overdose (Amaryl)?

    Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A Amyx overdose can cause life-threatening hypoglycemia.

    Symptoms of severe hypoglycemia include extreme weakness, confusion, tremors, sweating, fast heart rate, trouble speaking, nausea, vomiting, rapid breathing, fainting, and seizure (convulsions).

    Amyx

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    Contraindications

    • Hypersensitivity; sulfa allergy
    • Type 1 diabetes
    • Diabetic ketoacidosis (with or without coma)
    • Complicated gestational diabetes mellitus

    Effects of Drug Abuse

    • No information provided

    • See "What Are Side Effects Associated with Using Amyx?"

    • See "What Are Side Effects Associated with Using Amyx?"

    • Patients with risk of severe low blood sugar: elderly, debilitated, or malnourished; adrenal or pituitary insufficiency; patients with stress due to infection, fever, trauma, or surgery
    • If patient is exposed to stress, it may be necessary to discontinue Amyx and initiate insulinv
    • Use caution in liver/kidney impairment
    • Pregnancy, lactation
    • Increased risk of cardiovascularmortality
    • Persons allergic to other sulfonamide derivatives may develop allergic reaction to Amyx
    • Low blood sugar may be difficult to recognize in patients with autonomic neuropathy
    • Destruction of red blood cells (hemolytic anemia) may occur with glucose 6-phosphate dehydrogenase (G6PD) deficiency when treated with sulfonylurea agents
    • Fluid retention, which may exacerbate or lead to heart failure, may occur
    • Combination use with insulin and use in congestive heart failure NYHA Class I and II may increase risk of other cardiovascular effects
    • Potential risk of ischemic cardiovascular (CV) events relative to placebo reported in meta-analysis studies, but not confirmed in long-term cardiovascular outcome trial versus metformin or sulfonylurea
    • Dose-related edema, weight gain, and anemia may occur
    • Fluid buildup in the eye (macular edema) reported
    • Increased incidence of bonefracture reported
    • Post marketing reports for Amyx include severe allergic reaction (anaphylaxis), rapid swelling, and Stevens-Johnson Syndrome; promptly discontinue Amyx, assess for other causes, institute appropriate monitoring and treatment, and initiate alternative treatment for diabetes

    Pregnancy and Lactation

    • Use Amyx during pregnancy with caution if benefits outweigh risks. Animal studies show risk and human studies are not available, or neither animal nor human studies were done
    • Excretion of Amyx in breast milk is unknown, avoid when breastfeeding


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