Nortrilen capsules


  • Active Ingredient: Nortriptyline
  • 25 mg
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What is Nortrilen?

The active ingredient of Nortrilen brand is nortriptyline. Nortriptyline is a tricyclic antidepressant. Nortriptyline affects chemicals in the brain that may be unbalanced in people with depression. C19H21Nв€™HCl MW = 299.8 Each capsule, for oral administration, contains Nortriptyline hydrochloride equivalent to 10 mg, 25 mg, 50 mg, and 75 mg of Nortriptyline hydrochloride USP. In addition, each capsule contains the following inactive ingredients: black iron oxide, colloidal silicon dioxide, D&C Yellow #10 (aluminum lake), D&C Yellow #10, FD&C Blue #1 (aluminum lake), FD&C Blue #2 (aluminum lake), FD&C Green #3 (10, 50 and 75 mg only), FD&C Red #40 (aluminum lake), gelatin, I.M.S. 74 OP, magnesium stearate, pregelatinized corn starch, shellac, sodium lauryl sulfate and titanium dioxide.

Used for

Nortrilen is used to treat diseases such as: Burning Mouth Syndrome, Cyclic Vomiting Syndrome, Depression, Diabetic Peripheral Neuropathy, Dysautonomia, Irritable Bowel Syndrome, Migraine Prevention, Neuralgia, Neurosis, Pain, Panic Disorder, Postherpetic Neuralgia, Primary Nocturnal Enuresis, Reflex Sympathetic Dystrophy Syndrome, Smoking Cessation, Tinnitus, Vulvodynia.

Side Effect

Possible side effects of Nortrilen include: Bigger, dilated, or enlarged pupils (black part of the eye); mood or mental changes; lower back or side pain; depression; severe sunburn; waking to urinate at night; redness of the face, neck, arms, and occasionally, upper chest.

How to Buy Nortrilen capsules online?

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More common side effects

Some of the more common side effects that can occur with use of Nortrilen include:

  • low blood pressure
  • high blood pressure
  • confusion (mainly in seniors)
  • sleep problems
  • shakiness
  • dry mouth
  • blurry vision
  • constipation
  • skin rash
  • hives
  • itching
  • skin sensitivity to light
  • nausea
  • vomiting
  • diarrhea
  • stomach cramps
  • decreased sexual desire
  • unexpected weight loss or gain
  • sweating
  • headache

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

A Word From Verywell

While most people who take Nortrilen do not experience serious side effects from the medication, even mild side effects can be bothersome. When starting a new medication or adjusting your dosage, be sure to note any new or worsening symptoms and discuss them with your doctor. Together you can develop a plan to get the most out of Nortrilen's desired effects and manage unwanted side effects.

Rated Nortrilen (Pamelor) for Migraine Prophylaxis Report

I was suffering from IBS-D for years. I was prodded, scanned, tested and medicated without any results. After an episode which landed me in the ER I was referred to a internal Med doctor who took one look at my history and knew exactly what to do. He placed me on low dosage of Pamelor. After about a week of being on the medicine my life changed. I was finally able to eat without pain or worry of having to be around a bathroom. Although the medication made me quite sleepy at first and gave me dry mouth it was a small trade off for a pain free life. I also experienced debilitating migraines after returning from the gulf conflict in 2003. Pamelor was a life saver again! It was the first thing my neurologist put me on to control them! I’d recommend starting off at a lower 10mg dosage. I hope this helps someone who might be suffering from IBS and migraines like I did.

What Are Side Effects Associated with Using Nortrilen?

Side effects associated with use of Nortrilen, include the following:

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

How does Trazadone interact with Nortrilen. Can I safely take both?

Updated 2 Mar 2015 • 3 answers

Nortrilen and Alcohol

Talk to your doctor about consuming alcohol while taking this medication.

Nortrilen may make you drowsy. You should not drive a car or operate machinery until you know how this drug will affect you.

What should I discuss with my healthcare provider before taking Nortrilen (Aventyl HCl, Pamelor)?

You should not use Nortrilen if you are allergic to it, or if:

Do not use Nortrilen if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

To make sure Nortrilen is safe for you, tell your doctor if you have:

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Nortrilen. Your family or other caregivers should also be alert to changes in your mood or symptoms.

It is not known whether Nortrilen will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether Nortrilen passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Do not give this medicine to a child without medical advice. Nortrilen is not approved for use in children.


Nortrilen is a tricyclic antidepressant that is also used in smoking cessation. Nortrilen can cause mild and transient serum enzyme elevations and is rare cause of clinically apparent acute and chronic cholestatic liver injury.

Rated Nortrilen (Pamelor) for Postherpetic Neuralgia Report

Started at 10mg at bedtime for 3days, then titrated up to 20mg. Titrated up an additional 10mg every 7 days. Currently at 70mg once daily at bedtime. I haven't seen any effect for pain mitigation. I seem to wake at least once or twice during sleep, but can easily return to full sleep. I was hopeful this drug would help relieve my postherpetic neuralgia after reading other positive reviews, but, sadly, no response.

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