Rated Mirtawin (Remeron) for Depression Report
After seeing a psychiatrist for the last five years who said I was bipolar and put me on every psychotic drug out there with no luck to only find out I'm not bipolar. I've suffered with depression all my life. It runs in my mother's sign of the family. My new provider heard of the psychiatrist I was seeing and told me to stop and he would take care of my meds. I haven't really slept in the last 5 years or sleep all day, up all night. The Mirtawin has helped me so much with sleep. I feel like I'm coming out of a fog. waking up. All the other drugs I was put on caused me to have tremors which have for the most part gone away. I do take Lexapro along with Lamictal and the Mirtawin is the icing on the cake. What I would to share is our bodies are different. You can ask your doctor to take a swab test from your mouth to find out which drugs you are able to tolerate. All the drugs out there are not "one size fits all." I am in the medical field and now research every medication given to me and will ask my provider about what my research found and why he/she feels this is the medication for me. Be an advocate for yourself.
Before taking this medication, tell your doctor or pharmacist if you are allergic to it, or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: history or family history of psychiatric disorders (e.g., bipolar/manic-depressive disorder), history or family history of suicide attempts, liver disease, kidney disease, seizures, high blood cholesterol or triglyceride levels, heart disease (e.g., recent heart attack, angina), stroke, severe loss of body fluids (dehydration), low blood pressure, personal or family history of glaucoma (angle-closure type).
Mirtawin may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using Mirtawin, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using Mirtawin safely.
This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.
Older adults may be more sensitive to the side effects of this drug, especially drowsiness and QT prolongation (see above).
This medication should be used only when clearly needed during pregnancy. If this medication is used during the last 3 months of pregnancy, infrequently your newborn may develop symptoms including feeding or breathing difficulties, seizures, muscle stiffness, jitteriness or constant crying. Report any such symptoms to your doctor promptly. However, since untreated mental/mood disorders (such as depression) can be a serious condition, do not stop taking this medication unless your doctor directs you to do so. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.
This drug passes into breast milk. Consult your doctor before breast-feeding.
What other drugs will affect Mirtawin?
Using Mirtawin with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your current medicines. Many drugs can affect Mirtawin, especially:
tryptophan (sometimes called L-tryptophan);
an antibiotic - clarithromycin, rifampin, rifampicin, telithromycin;
antiviral medicine to treat HIV/AIDS - indinavir, nelfinavir, ritonavir, saquinavir;
medicine to treat mood disorders, thought disorders, or mental illness - such as lithium, other antidepressants, or antipsychotics;
migraine headache medicine - sumatriptan, rizatriptan, Imitrex, Maxzalt, and others; or
This list is not complete and many other drugs may interact with Mirtawin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
1. About Mirtawin
Mirtawin is an antidepressant medicine. It's used to treat depression and sometimes obsessive compulsive disorder and anxiety disorders.
Mirtawin is available only on prescription. It comes as tablets or as a liquid you swallow.
What is Mirtawin, and how does it work (mechanism of action)?
Mirtawin is a tetracyclic antidepressant similar to maprotiline (Ludiomil) and tricyclic antidepressants, for example, desipramine (Norpramin). Depression is an all-pervasive sense of sadness and gloom. It is believed that in some patients with depression, abnormal levels of neurotransmitters (chemicals that nerves use to communicate with each other) may be the cause of their depression. Mirtawin elevates mood by raising the level of neurotransmitters (norepinephrine and serotonin) in nerves of the brain. Mirtawin also blocks the effect of histamine. Mirtawin was approved by the FDA in 1996.
On this page
- About Mirtawin
- Key facts
- Who can and can't take Mirtawin
- How and when to take it
- Side effects
- How to cope with side effects
- Pregnancy and breastfeeding
- Cautions with other medicines
- Common questions
You should not take Mirtawin if you are also taking tryptophan (sometimes called L-tryptophan).
Do not use Mirtawin if you have used an MAO inhibitor or methylene blue injection n the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Some people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Mirtawin. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Do not give this medicine to anyone younger than 18 years old without the advice of a doctor. This medicine is not approved for use in children.
It may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment.
Drinking alcohol can increase certain side effects of Mirtawin.
Mirtawin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Do not stop taking this medicine abruptly. Talk to your doctor before stopping this medicine.
In healthy, male, Caucasian patients (n=24), coadministration of the potent CYP3A4 inhibitor ketoconazole (200 mg b.i.d. for 6.5 days) increased the peak plasma levels and the AUC of a single 30- mg dose of Mirtawin by approximately 40% and 50%, respectively.
Caution should be exercised when coadministering Mirtawin with potent CYP3A4 inhibitors, HIV protease inhibitors, azole antifungals, erythromycin, or nefazodone.
REMERON (Mirtawin) Tablets are indicated for the treatment of major depressive disorder.
The efficacy of REMERON in the treatment of major depressive disorder was established in 6-week controlled trials of outpatients whose diagnoses corresponded most closely to the Diagnostic and Statistical Manual of Mental Disorders - 3rd edition (DSM-III) category of major depressive disorder (see CLINICAL PHARMACOLOGY).
A major depressive episode (DSM-IV) implies a prominent and relatively persistent (nearly every day for at least 2 weeks) depressed or dysphoric mood that usually interferes with daily functioning, and includes at least 5 of the following 9 symptoms: depressed mood, loss of interest in usual activities, significant change in weight and/or appetite, insomnia or hypersomnia, psychomotor agitation or retardation, increased fatigue, feelings of guilt or worthlessness, slowed thinking or impaired concentration, a suicide attempt, or suicidal ideation.
The effectiveness of REMERON in hospitalized depressed patients has not been adequately studied.
The efficacy of REMERON in maintaining a response in patients with major depressive disorder for up to 40 weeks following 8 to 12 weeks of initial open-label treatment was demonstrated in a placebocontrolled trial. Nevertheless, the physician who elects to use REMERON for extended periods should periodically re-evaluate the long-term usefulness of the drug for the individual patient (see CLINICAL PHARMACOLOGY).
Rated Mirtawin (Remeron) for Depression Report
I have been taking Mirtawin for nearly 4 months. It helped me sleep to begin with but In the end it I was staying up all night. Then had a horrible allergic reaction to it. My whole body was covered in hives and my body was soo itchy. I have never ever experienced anything like it. I have now been taken off Mirtawin all of a sudden and now I can’t sleep at all. I’m lucky if I get 4 hours sleep a night!Also, the long-term with an antidepressant. I started off with 30mg at night, I took it about an hour before I wanted to go to bed and it worked amazing for me. These can include:. A nightmare is rare for me but does happen on occasion. Mirtawin is characterized by active metabolism with the formation of several metabolites. These drugs are often used to treat similar conditions. Mirtawin side effects in more detail. For people with glaucoma or other eye problems: This drug may dilate your pupils. Rated Mirtawin Remeron for Depression Report after trying citalopram for a few unsuccessful weeks my doctor put me on to Mirtawin. At age 38 I ran 2 miles in 12 minutes. Usually dosages for the treatment of sleep will start at 15mg. Feel free to post a reply in this discussion and if you have any questions I can help with, I will happily answer.