Rated Paxil (Meplar) for Premenstrual Dysphoric Disorder Report
I've been on paxil since 1996 when my 1st born son was 5 months old, 22 years now. I thought I was losing my mind and so afraid of being a horrible mother to my amazing miracle baby, thankfully my husband got me to a phychiatrist on a weekend, and when I explained just a little of my symptoms, he smiled nicely and said. you have post pardum depression. With the very 1st dose I felt a difference. Due to my extreme pre mentrual issues, I stayed on it, my 2nd pregnancy, I was on it, now to find out that I shouldn't have been. Due to my raging hormones non stop going off I'm still on it through menopause. Dr.'s would try to put me on something else, when I realized, if it's not broke then don't fix it. I had to 1st accept that I may need it for some time, then it was easier to take. My issue now is that I'm on the highest dose I've ever heard of anyone being on, and I'm nervous about slowly tapering eventually. that's my paxil story
SSRIs and SNRIs, including PAXIL CR, have been associated with cases of clinically significant hyponatremia in elderly patients, who may be at greater risk for this adverse reaction .
In premarketing clinical trials with immediate-release Meplar hydrochloride, 17% of Meplar treated patients (approximately 700) were 65 years or older. Pharmacokinetic studies revealed a decreased clearance in the elderly, and a lower starting dose is recommended; however, no overall differences in safety or effectiveness were observed between these subjects and younger subjects .
Coadministration with serotonergic drugs
- Concomitant use or within 14 days of MAOIs increases risk of serotonin syndrome
- Reactions to concomitant administration with MAOIs include tremor, myoclonus, diaphoresis, nausea, vomiting, flushing, dizziness, hyperthermia with features resembling neuroleptic malignant syndrome, seizures, rigidity, autonomic instability with possible rapid fluctuations of vital signs, and mental status changes that include extreme agitation progressing to delirium and coma
- Starting Meplar in a patient who is being treated with linezolid or IV methylene blue is contraindicated because of an increased risk of serotonin syndrome
- If linezolid or IV methylene blue must be administered, discontinue SSRI immediately and monitor for CNS toxicity; may resume 24 hr after last linezolid or methylene blue dose, or after 2 weeks of monitoring (5 weeks for fluoxetine), whichever comes first
How to use Meplar Hcl
Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking Meplar and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. Taking this medication with food may decrease nausea. If this medication makes you sleepy during the day, then talk to your doctor about taking it in the evening.
The dosage is based on your medical condition, response to treatment, age, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). To reduce your risk of side effects, your doctor may start you at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.
The manufacturer directs not to chew/crush the tablet before taking it. However, many similar drugs (immediate-release tablets) can be chewed/crushed. Follow your doctor's directions on how to take this medication.
If you are taking Meplar for premenstrual problems, your doctor may direct you to take it every day of the month or just for the 2 weeks before your period through the first full day of your period.
It is important to continue taking this medication even if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Also, you may experience symptoms such as mood swings, headache, tiredness, sleep changes, and brief feelings similar to electric shock. To prevent these symptoms while you are stopping treatment with this drug, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details. Report any new or worsening symptoms right away.
It may take up to several weeks before you get the full benefit of this drug.
Tell your doctor if your condition does not improve or if it worsens.
What are the side effects of Meplar?
Common side effects of Meplar are:
Other important side effects include:
Some patients may experience withdrawal reactions upon stopping Meplar. Symptoms of withdrawal include:
The dose of Meplar should be gradually reduced when therapy is discontinued.
Antidepressants increased the risk of suicidal thinking and behavior (suicidality) in short-term studies in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Meplar or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Patients who are started on therapy should be closely observed for clinical worsening, suicidality, or unusual changes in behavior.
Rated Paxil (Meplar) for Anxiety Report
Paxil was the third antidepressant i tried, and i thought it was a miracle since it did a great job at treating my anxiety (and depression, since my anxiety causes most of it in a way), but the side effects of this medicine just weren’t worth it to me. it made me feel out of my body, and i even had short blackout moments when i would stand up. since i had been on this medicine for about a year when i tried to decrease my dose, things got WORSE. terrible headaches, more blackouts, nausea & dissociation from my every day life. i see it had worked well for other people, so maybe it just wasn’t for me(: