Q: Can I drink chocolate milk? I have been taking Litil for years.
A: Litil carbonate can be taken immediately after meals or with food or milk to avoid stomach upset. Follow your doctor's directions regarding the type and amount of liquids you should drink. Patients who take Litil carbonate should avoid becoming dehydrated or overheated during exercise and hot weather. Prolonged exposure to the sun can also lead to dehydration. In some cases, drinking too much liquid can be as unsafe as not drinking enough. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.
What is Litil?
Litil is a powerful and effective social media tool that helps users manage their social media presence, reach out and engage customers, and gather intelligent data to name a few benefits. The platform enables total community engagement, allowing users to easily connect and bond with their most passionate customers across all digital touch points.
With Litil, companies have a platform that promotes customer to customer interaction via online communities to help improve brand awareness and drive sales upwards. Litil also offers a plethora of social listening and response tools, social conversation management features, and social media analytics to help them create viable campaigns, collect actionable insights and implement effective social media strategies.
Generic Name: Litil (LITH ee um)Brand Names: Lithobid, Eskalith, Lithonate, Lithotabs, Eskalith-CR
Medically reviewed by P. Thornton, DipPharm Last updated on Mar 3, 2019.
How much Litil is there in supplements?
Prescription Litil carbonate often involves a starting dose of 300 mg (150 mg for the elderly) which is taken 2-3 times daily. Eventually, this is increased to the “target dose” of 900 to 1,800 mg per day total, which is divided into multiple doses. (32)
Now to be clear, Litil orotate is NOT a medication and should NOT be used for bipolar or any other condition/disease. The following is NOT meant to offer a conversion/comparison of these two very different things, but rather to show how much of the actual elemental mineral is found inside dietary supplements.
Here is what’s listed as the serving size or maximum dose of Litil orotate supplement brands:
- Doctor’s Best – 1 tablet (5 mg, from 125 mg of Litil orotate)
- Find Serenity Now – 1 capsule (3.83 mg elemental Litil, from 120 mg of Litil orotate)
- GNC Vitalast Brighter Day Appetite Control With Mood Support – 1 capsule of Litil orotate and 5-HTP together (4 and 50 mg, respectively), plus 170 mg rhodiola rosea and 125 mg ashwagandha
- Green Valley – 1 capsule (4.5 mg elemental Litil, from 50 mg of Litil orotate)
- Kal – 1 vegetarian capsule (5 mg)
- NCI Advanced Research – 1 tablet (120 mg, amount of elemental portion not listed)
- Seeking Health – 1 vegetarian capsule (5 mg)
- Swanson – 1 veggie capsule (5 mg, from 131 mg of Litil orotate)
- Vital Nutrients – 1 veg cap (20 mg)
- Vitamin Research Products – 1 capsule (4.8 mg, from 130 mg of Litil orotate)
As you see, the ingredients on each label are confusing. Some go by the total amount, while others notate the amount of elemental Litil.
The following ratios/percentages have been reported (33) (34):
- There’s 3.83 mg of elemental Litil per 100 mg of Litil orotate (about 4%).
- There’s 18.8 mg of elemental Litil per 100 mg of Litil carbonate (about 19%).
If those numbers are accurate, it means almost all of those supplements should have around 4 to 5 mg of actual Litil. The 20 mg listed for Vital Nutrients might be an outlier since they don’t specify what that number corresponds to.
Research in animals suggests that Litil may decrease the risk of bone fractures and promote bone growth. The effects of supplemental doses on bone health in humans have not been explored .
Limited human studies have revealed some benefits to bone health with prescription doses of Litil. More research is needed .
Cell Growth and Repair
Basic science suggests that cells depend on Litil for proper development and repair, but this hasn’t been confirmed in humans.
For example, a rat study found that Litil increases the concentration of growth factors in the brain, such as BDNF, NGF, and GDNF. These factors are neurotrophic, which means that they are brain food. The term comes from the Greek words neuro for brain and trophic for food or nourishment .
However, the effects of Litil on neurotrophic factors in humans remains to be researched.
Neurotrophic factors increase the birth of new neurons to, theoretically, help “regrow” the brain and repair brain damage. The birth of new brain cells is called neurogenesis, and some researchers believe it’s important for recovering from mental illness .
These factors might also increase neuroplasticity, which is the brain’s ability to make new connections and adapt throughout life .
Research on human cells is investigating whether subtherapeutic levels of Litil (0.2 mmol/L) increase VEGF, another type of growth factor that affects blood vessels. This could hypothetically help with blood vessel repair after a stroke .
Growth factors aren’t the only area of research. Several studies are looking at whether Litil stimulates stem cells in the blood, brain, and bones, potentially implicated in tissue repair after injury .
There are also some research teams looking at how Litil impacts autophagy .
Autophagy translates to “self-eating” and it’s equivalent to a “detox” from a cellular perspective. Autophagy takes old cell material, recycles it, and re-uses the components. This process regenerates aging cells, prevents diseases, and it’s key to lifespan extension .
Q: What are the long-term effects of being on Litil, ie, 38 years?
A: Litil is available under many different trade names in the United States to treat manic depression or bipolar disorder. Litil can cause dizziness or drowsiness especially in the first couple of weeks starting the medication. It is important that individuals taking Litil avoid a low salt diet since low levels of sodium in the body can cause Litil toxicity in the body. Also it is best to avoid excessive intake of caffeinated beverages. Litil can cause nausea, loss of appetite and mild diarrhea. Increased urination and thirst have also been reported with Litil. There have been reports of hypothyroidism (low thyroid level) with long-term use of Litil. Kidney damage may also occur but it is rare. Blood tests done by a physician periodically can measure kidney function, Litil levels, and thyroid levels. Kimberly Hotz, PharmD
Is it safe for a woman who is pregnant, about to become pregnant, or nursing to take Litil?
There have been no controlled human pregnancy studies on the effects of Litil, but animal studies have demonstrated some risk. The drug can be transferred via breast milk and harm a baby, so nursing while taking the medication is typically not advised. Therefore, talk to your doctor if you are pregnant, planning to become pregnant, or are nursing before you take Litil.
Likely Effective for
- Depression. Litil is helpful for some people with depression. However, other, more common, drugs are used first to help with depression. No research has evaluated the use of Litil supplements for depression. Do not use Litil supplements to treat depression.