4. How and when to take it
Take Esram once a day. You can take it with or without food.
You can take Esram at any time of day, as long as you stick to the same time every day.
If you have trouble sleeping, it's best to take it in the morning.
Certain water pills can decrease sodium levels in your body. Esram may also decrease sodium. Taking water pills with these drugs may increase your risk of low sodium levels. Examples of these drugs include:
6. How to cope with s >
What to do about:
- a dry mouth - chew sugar-free gum or sugar-free sweets
- sweating a lot - try wearing loose clothing, using a strong anti-perspirant, and keeping cool using a fan, if possible. If this doesn't control the problem, talk to your doctor. You may need to try a different antidepressant.
- being unable to sleep - take Esram first thing in the morning
- feeling sleepy- take Esram in the evening and cut down the amount of alcohol you drink. Do not drive or use tools or machinery if you're feeling sleepy. If this doesn't help, talk to your doctor.
- feeling tired or weak - stop what you're doing and sit or lie down until you feel better. Do not drive or use tools or machinery if you're feeling tired. Do not drink alcohol as it'll make you feel worse.
How should this medicine be used?
Esram comes as a tablet and a solution (liquid) to take by mouth. It is usually taken once a day with or without food. To help you remember to take Esram, take it at around the same time every day, in the morning or in the evening. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Esram exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor may start you on a low dose of Esram and increase your dose after 1 week.
It may take 1 to 4 weeks or longer before you feel the full benefit of Esram. Continue to take Esram even if you feel well. Do not stop taking Esram without talking to your doctor. If you suddenly stop taking Esram, you may experience withdrawal symptoms such as mood changes, irritability, agitation, dizziness, numbness or tingling in the hands or feet, anxiety, confusion, headache, tiredness, and difficulty falling asleep or staying asleep. Your doctor will probably decrease your dose gradually.
Male And Female Sexual Dysfunction With SSRIs
Although changes in sexual desire, sexual performance, and sexual satisfaction often occur as manifestations of a psychiatric disorder, they may also be a consequence of pharmacologic treatment. In particular, some evidence suggests that SSRIs can cause such untoward sexual experiences.
Reliable estimates of the incidence and severity of untoward experiences involving sexual desire, performance, and satisfaction are difficult to obtain, however, in part because patients and physicians may be reluctant to discuss them. Accordingly, estimates of the incidence of untoward sexual experience and performance cited in product labeling are likely to underestimate their actual incidence.
TABLE 5: Incidence of Sexual Side Effects in Placebo-Controlled Clinical Trials Adverse Event Lexapro Placebo In Males Only (N=407) (N = 383) Ejaculation Disorder (primarily ejaculatory delay) 12% 1% Libido Decreased 6% 2% Impotence 2%
There are no adequately designed studies examining sexual dysfunction with Esram treatment.
Priapism has been reported with all SSRIs.
While it is difficult to know the precise risk of sexual dysfunction associated with the use of SSRIs, physicians should routinely inquire about such possible side effects.
Q: I am on Lexapro daily, and I've gained 20 lbs. What can I do to avoid continuous weight gain?
A: Lexapro (Esram) belongs to the SSRI class of drugs and affects chemicals in the brain that may become unbalanced and cause depression or anxiety. Lexapro is used to treat anxiety in adults and major depressive disorder in adults and adolescents who are at least 12 years old. The SSRIs and a similar class, the serotonin-norepinephrine reuptake inhibitors (SSNRIs), are some of the most widely used depression medications on the market. These two classes of drugs have become so widely prescribed because their side effects are limited compared to some of the older antidepressants. However, they still do have some side effects. And weight gain can be a common side effect of both of these classes of drugs. Keep in mind that patients may react differently to different medications within these classes. If side effects, like weight gain, become bothersome, it sometimes helps to switch medications. Consult your health care provider for specific recommendations. Available SSRIs include paroxetine (Paxil), fluoxetine (Prozac), fluvoxamine (Luvox), sertraline (Zoloft), Esram (Lexapro), and citalopram (Celexa). The SSNRIs include venlafaxine (Effexor) and duloxetine (Cymbalta). Do not stop any medication or change the dose without first talking to your provider. Suddenly stopping Lexapro can cause withdrawal symptoms that may be severe. Your health care provider is best able to guide your choice of treatment based on your specific circumstances. Sarah Lewis, PharmD
What other drugs will affect Esram (Lexapro)?
Taking Esram with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking a sleeping pill, narcotic medication, muscle relaxer, or medicine for anxiety, depression, or seizures.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Esram, especially:
- any other antidepressant;
- medicine to treat anxiety, mood disorders, or mental illness;
- lithium, St. John's wort, tramadol, or tryptophan (sometimes called L-tryptophan);
- a blood thinner--warfarin, Coumadin, Jantoven;
- migraine headache medication--sumatriptan, rizatriptan, and others;
- narcotic pain medication--fentanyl or tramadol; or
- stimulants or ADHD medication--Adderall, Concerta, Ritalin, and others;
This list is not complete. Other drugs may interact with Esram, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Certain migraine drugs called triptans may work similarly to Esram. Taking them with Esram could increase your risk of side effects. Examples of migraine drugs include:
What should I avoid while taking Esram (Lexapro)?
Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. Using an NSAID with Esram may cause you to bruise or bleed easily.
Drinking alcohol with this medicine can cause side effects.
Esram may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
What are the possible side effects of Esram (Lexapro)?
Get emergency medical help if you have signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have:
- blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
- racing thoughts, unusual risk-taking behavior, feelings of extreme happiness or sadness;
- low levels of sodium in the body--headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady; or
- severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Common side effects may include:
- dizziness, drowsiness, weakness;
- sweating, feeling shaky or anxious;
- sleep problems (insomnia);
- dry mouth, loss of appetite;
- nausea, constipation;
- weight changes; or
- decreased sex drive, impotence, or difficulty having an orgasm.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What Is Lexapro?
Lexapro (Esram) is type of antidepressant called a selective serotonin reuptake inhibitor (SSRI) used to treat anxiety in adults and major depressive disorder in adults and adolescents who are at least 12 years old.