Eostar tablets


  • Active Ingredient: Citalopram
  • 40 mg, 20 mg
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What is Eostar?

The active ingredient of Eostar brand is citalopram. Citalopram is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). The molecular formula is C20H22BrFN2O and its molecular weight is 405.35. Citalopram hydrobromide occurs as a fine white to off-white powder. Citalopram hydrobromide is sparingly soluble in water and soluble in ethanol. Citalopram hydrobromide 10 mg capsules have an ivory body and yellow cap and contain citalopram hydrobromide equivalent to 10 mg citalopram base. Citalopram hydrobromide 20 mg capsules have an ivory body and pink cap and contain citalopram hydrobromide equivalent to 20 mg citalopram base. Citalopram hydrobromide 40 mg capsules have an ivory body and a green cap and contain citalopram hydrobromide equivalent to 40 mg citalopram base. The capsules also contain the following inactive ingredients: corn starch, crospovidone, edible inks, gelatin, lactose monohydrate, magnesium stearate, titanium dioxide, and yellow iron oxide. The following coloring agents are used in the yellow (10 mg) capsules: D&C Red No. 28, D&C Yellow No. 10, and FD&C Yellow No. 6. The following coloring agents are used in the pink (20 mg) capsules: D&C Red No. 28, D&C Yellow No. 10, FD&C Blue No. 1, and FD&C Red No. 40. The following coloring agents are used in the green (40 mg) capsules: D&C Yellow No. 10 and FD&C Blue No. 1.

Used for

Eostar is used to treat diseases such as: Agitation, Anxiety and Stress, Bipolar Disorder, Body Dysmorphic Disorder, Borderline Personality Disorder, Depression, Dissociative Identity Disorder, Generalized Anxiety Disorder, Hot Flashes, Neuralgia, Obsessive Compulsive Disorder, Occipital Neuralgia, Panic Disorder, Persistent Depressive Disorder, Postpartum Depression, Premenstrual Dysphoric Disorder, Severe Mood Dysregulation, Somatoform Pain Disorder, Trichotillomania, Vulvodynia.

Side Effect

Possible side effects of Eostar include: talking or acting with excitement you cannot control; trouble with holding or releasing urine; watering of the mouth; increased yawning; chest pain; rapid weight gain; confusion as to time, place, or person.

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Eostar Dosage

Eostar comes in tablet form, in 10, 20, and 40 milligrams (mg), or as a liquid solution taken orally.

Your doctor will likely prescribe a 20 mg dose of Eostar, taken once a day, to start. That dose could be increased gradually to 40 mg a day as you adjust to the medication.

It can be taken with or without food.

It may take one to four weeks before you notice the full benefit of Eostar, so continue your medication even if you feel well.

Q: Is Eostar causing my weight gain?

A: Your question concerns whether weight gain is a side effect of Eostar (Celexa) //www.everydayhealth.com/drugs/Eostar. Weight changes are a common side effect of Eostar. In some patients, that shows as a weight loss; others, unfortunately, put on extra pounds as a side effect. It is always a good idea to check with one's health care provider in matters like this. Please consult your health care provider for guidance in your specific case. Gregory Latham, RPh

What is Eostar?

Eostar is an antidepressant belonging to a group of drugs called selective serotonin reuptake inhibitors (SSRIs).

Eostar is used to treat depression.

Eostar may also be used for purposes not listed in this medication guide.

Other Events Observed During The Premarketing Evaluation Of Celexa (Eostar HBr)

Following is a list of WHO terms that reflect treatment-emergent adverse events, as defined in the introduction to the ADVERSE REACTIONS section, reported by patients treated with Celexa at multiple doses in a range of 10 to 80 mg/day during any phase of a trial within the premarketing database of 4422 patients. All reported events are included except those already listed in Table 3 or elsewhere in labeling, those events for which a drug cause was remote, those event terms which were so general as to be uninformative, and those occurring in only one patient. It is important to emphasize that, although the events reported occurred during treatment with Celexa, they were not necessarily caused by it.

Events are further categorized by body system and listed in order of decreasing frequency according to the following definitions: frequent adverse events are those occurring on one or more occasions in at least 1/100 patients; infrequent adverse events are those occurring in less than 1/100 patients but at least 1/1000 patients; rare events are those occurring in fewer than 1/1000 patients.

Cardiovascular- Frequent: tachycardia, postural hypotension, hypotension. Infrequent: hypertension, bradycardia, edema (extremities), angina pectoris, extrasystoles, cardiac failure, flushing, myocardial infarction, cerebrovascular accident, myocardial ischemia. Rare: transient ischemic attack, phlebitis, atrial fibrillation, cardiac arrest, bundle branch block.

Central And Peripheral Nervous System Disorders - Frequent: paresthesia, migraine. Infrequent: hyperkinesia, vertigo, hypertonia, extrapyramidal disorder, leg cramps, involuntary muscle contractions, hypokinesia, neuralgia, dystonia, abnormal gait, hypesthesia, ataxia. Rare: abnormal coordination, hyperesthesia, ptosis, stupor.

General - Infrequent: hot flushes, rigors, alcohol intolerance, syncope, influenza-like symptoms. Rare: hayfever.

Hemic and Lymphatic Disorders - Infrequent: purpura, anemia, epistaxis, leukocytosis, leucopenia, lymphadenopathy. Rare: pulmonary embolism, granulocytopenia, lymphocytosis, lymphopenia, hypochromic anemia, coagulation disorder, gingival bleeding.

Metabolic and Nutritional Disorders - Frequent: decreased weight, increased weight. Infrequent: increased hepatic enzymes, thirst, dry eyes, increased alkaline phosphatase, abnormal glucose tolerance. Rare: bilirubinemia, hypokalemia, obesity, hypoglycemia, hepatitis, dehydration.

Musculoskeletal System Disorders - Infrequent: arthritis, muscle weakness, skeletal pain. Rare: bursitis, osteoporosis.

Psychiatric Disorders - Frequent: impaired concentration, amnesia, apathy, depression, increased appetite, aggravated depression, suicide attempt, confusion. Infrequent: increased libido, aggressive reaction, paroniria, drug dependence, depersonalization, hallucination, euphoria, psychotic depression, delusion, paranoid reaction, emotional lability, panic reaction, psychosis. Rare: catatonic reaction, melancholia.

Reproductive Disorders /Female* - Frequent: amenorrhea. Infrequent: galactorrhea, breast pain, breast enlargement, vaginal hemorrhage.

*% based on female subjects only: 2955

Respiratory System Disorders - Frequent: coughing. Infrequent: bronchitis, dyspnea, pneumonia. Rare: asthma, laryngitis, bronchospasm, pneumonitis, sputum increased.

Urinary System Disorders - Frequent: polyuria. Infrequent: micturition frequency, urinary incontinence, urinary retention, dysuria. Rare: facial edema, hematuria, oliguria, pyelonephritis, renal calculus, renal pain.

What are the side effects of Eostar?

The most common side effects associated with Eostar are

Overall, between 1 in 6 and 1 in 5 persons experience a side effect. Eostar is also associated with sexual dysfunction. Some patients may experience withdrawal reactions upon stopping Eostar. Symptoms of withdrawal include

Antidepressants increased the risk of suicidal thinking and behavior (suicidality) in short-term studies in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Eostar or any other antidepressant in a child or adolescent must balance this risk with the clinical need. Patients who are started on therapy should be closely observed for clinical worsening, suicidality, or unusual changes in behavior.

Other uses for this medicine

Eostar is also sometimes used to treat eating disorders, alcoholism, panic disorder (condition that causes sudden attacks of extreme fear with no apparent cause), premenstrual dysphoric disorder (a group of physical and emotional symptoms that occur before the menstrual period each month), and social phobia (excessive anxiety about interacting with others). Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

The potential relationship between the dose of Celexa administered and the incidence of adverse events was examined in a fixed-dose study in depressed patients receiving placebo or Celexa 10, 20, 40, and 60 mg. Jonckheere's trend test revealed a positive dose response (p Treatment Celexa (425 males) Placebo (194 males) Abnormal Ejaculation (mostly ejaculatory delay) 6.1% (males only) 1% (males only) Libido Decreased 3.8% (males only)

In female depressed patients receiving Celexa, the reported inc >

There are no adequately designed studies examining sexual dysfunction with Eostar treatment.

Priapism has been reported with all SSRIs.

While it is difficult to know the precise risk of sexual dysfunction associated with the use of SSRIs, physicians should routinely inquire about such possible side effects.

Long-Term Psychological Changes from Eostar Abuse

Some people may experience “Prozac poop-out,” a condition that occurs when an SSRI like Eostar suddenly becomes less effective after months or years. A person may take Celexa every day, as prescribed, and respond well until suddenly one day, they do not, leading to a relapse in depression symptoms. People who experience this phenomenon can increase the dose or switch to another antidepressant with a different mechanism of action. 6

Tricyclic antidepressants (TCAs)

Caution should be used when using Eostar with a TCA. This can result in higher levels of the TCA in your body and more side effects. Tricyclic antidepressants include:

  • amitriptyline
  • imipramine
  • nortriptyline

Responses (2)

Did you hear it right? It takes about 4 WEEKS to reach peak effect. 10 mg isn't much at all. Your dr is starting you out slow. Its going to need to be increased to 20 in a week or so. Your husband is correct. The suicidal warning is something that all antidepressants carry. Its a requirement from the FDA. It does not mean that you are going to become suicidal. Side effects are listed if 1% of the population has had them. Most people have very few of them if any.

yes i did hear right as my husband was with meand i asked him did i hear right he said 4 days before they start to work not for the full affect i have read a few ppls comments on this medication n some have said 4 days some say a week some 4wks and 1 person said they could feel the first few hours i surpose it depends how medication works with ur body . just wanted 2 find best time of day just rang boots pharmecy and she said it dosnt matter the time most ppl take it n the morning i just wanted 2 no as i have kids n my youngest is nly months old so wanted to be safe and she said it can start 2 work on my problems in 4 days n will get the full work of it in weeks

Hi, Kaismama is correct in saying that it takes 4 weeks (give or take) for Eostar to work to it's full potential. You can start to feel better before this time, but 4 weeks is the guideline time period for when you can expect significant results. The majority of people take Eostar in the morning. It can be taken at night, but can interrupt your sleep pattern. It is important to take the medication at the same time every day. There are several potential side effects that you could suffer with, and these types of medications are known to make you feel worse before you feel better (up to 4 weeks, but not necessarily this long), to what extent varies from person to person. I started taking Eostar several years ago now and it has changed my life for the better. I would always suggest giving it a try. My mum also takes 10mg to treat her anxiety. Your doctor may keep you on this dose or possibly increase it after 3 or 4 weeks. I hope you find the same success as i have.

How to use Eostar HBR

Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking Eostar and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication with or without food as directed by your doctor, usually once daily in the morning or evening. The dosage is based on your medical condition, response to treatment, age, laboratory tests, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). The maximum dosage for Eostar is 40 milligrams per day.

If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

To reduce your risk of side effects, your doctor may direct you to start taking this drug at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

It is important to continue taking this medication even if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Also, you may experience symptoms such as mood swings, headache, tiredness, sleep changes, and brief feelings similar to electric shock. To prevent these symptoms while you are stopping treatment with this drug, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details. Report any new or worsening symptoms right away.

It may take 1 to 4 weeks to feel a benefit from this drug and up to several weeks before you get the full benefit.

Tell your doctor if your condition does not improve or if it worsens.

What is Eostar, and how does it work (mechanism of action)?

Eostar is an antidepressant medication that affects neurotransmitters, the chemicals that nerves within the brain use to communicate with each other. Neurotransmitters are manufactured and released by nerves and then travel and attach to nearby nerves. Thus, neurotransmitters can be thought of as the communication system of the brain. Many experts believe that an imbalance among neurotransmitters is the cause of depression. Eostar works by preventing the uptake of one neurotransmitter, serotonin, by nerve cells after it has been released. Since uptake is an important mechanism for removing released neurotransmitters and terminating their actions on adjacent nerves, the reduced uptake caused by Eostar results in more free serotonin in the brain to stimulate nerve cells. Eostar is in the class of drugs called selective serotonin reuptake inhibitors (SSRIs), a class that also contains fluoxetine (Prozac), paroxetine (Paxil) and sertraline (Zoloft). Eostar was approved by the FDA in July 1998.

Eostar is approved for treating depression. It is also used off-label for treating:

Rated Eostar (Celexa) for Posttraumatic Stress Disorder (PTSD) Report

I have been prescribed Eostar and I’m already feeling better. I am not feeling down at all, (couldn’t go more than about 3 hours without spiralling in to a huge downer). So far so good but it’s early days. No side effects apart from the first day I took it, I felt a bit dizzy and had to sit down, but it only lasted an hour and was fairly mild. Once I took it the second d day, no dizziness whatsoever and so on. I highly recommend this as I have always suffered with severe depression and anxiety/panic attacks since childhood and recently have been through something that was life changing and suffered with PTSD. Since that I was very very angry all the time and very teary, couldn’t even sit still for more than a couple minutes- doesn’t sound like much but I was able to sit down for a couple hours today and feel great about it! Such basic things that I couldn’t do just a while back, I’m able to do now like anyone normal. I finally feel like a person!

Q: I'm currently taking 20 mg daily of Eostar. Since a mild depression has returned, my doctor recommended boosting the dose to 40 mg per day. At the risk of sounding vain, I am also working on losing weight as I have been for several months now. My weight loss has been very slow but steady (approx. one pound per week) and I would hate to sabotage it by taking more medicine. Am I being unreasonable?

A: Regarding Eostar and its use in the treatment of depression, the normal starting dose is 20 mg daily. It is quite typical for many patients to have their dose of Eostar increased to 40mg. The usual effective dose of Eostar in adults is 20 to 40 mg/day, with a maximum dose of 60 mg per day. As far as side effects go, while Eostar has been associated with rapid weight gain, researchers at the University of Maryland Medical Center found that less than 10% of patients experienced weight gain with Eostar. In a different study, it was concluded that patients taking Eostar actually experienced a weight loss of 0.5Kg (about 1 pound). It is always good to communicate with one's health care provider(s) in matters such as this. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Gregory Latham, MS, RPh

Before taking this medicine

You should not use this medicine if you are allergic to Eostar or esEostar (Lexapro), or if you also take pimozide.

Do not use Eostar if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

To make sure Eostar is safe for you, tell your doctor if you have:

a bleeding or blood clotting disorder;

liver or kidney disease;

seizures or epilepsy;

heart disease, heart failure, a heart rhythm disorder, slow heartbeats, or recent history of heart attack;

personal or family history of Long QT syndrome;

an electrolyte imbalance (such as low levels of potassium or magnesium in your blood);

bipolar disorder (manic depression); or

a history of drug abuse or suicidal thoughts.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Taking an SSRI antidepressant during pregnancy may cause serious lung problems or other complications in the baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking this medicine during pregnancy without your doctor's advice.

Eostar can pass into breast milk and may harm a nursing baby. You should discuss the risks and benefits of using Eostar if you are breast-feeding.

Do not give this medicine to anyone under 18 years old without medical advice. Eostar is not approved for use in children.

Mixing Eostar with herbal remedies and supplements

Do not take St John's wort, the herbal remedy for depression, while you're being treated with Eostar as this will increase your risk of side effects.

Pregnancy and Eostar

Discuss a current or planned pregnancy with your physician before taking this drug.

Also talk to your doctor if you plan to breastfeed while on Eostar. This drug is known to pass into breast milk.

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