Citaxin tablets

Citaxin

  • Active Ingredient: Citalopram
  • 40 mg, 20 mg
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What is Citaxin?

The active ingredient of Citaxin brand is citalopram. Citalopram is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). The molecular formula is C20H22BrFN2O and its molecular weight is 405.35. Citalopram hydrobromide occurs as a fine white to off-white powder. Citalopram hydrobromide is sparingly soluble in water and soluble in ethanol. Citalopram hydrobromide 10 mg capsules have an ivory body and yellow cap and contain citalopram hydrobromide equivalent to 10 mg citalopram base. Citalopram hydrobromide 20 mg capsules have an ivory body and pink cap and contain citalopram hydrobromide equivalent to 20 mg citalopram base. Citalopram hydrobromide 40 mg capsules have an ivory body and a green cap and contain citalopram hydrobromide equivalent to 40 mg citalopram base. The capsules also contain the following inactive ingredients: corn starch, crospovidone, edible inks, gelatin, lactose monohydrate, magnesium stearate, titanium dioxide, and yellow iron oxide. The following coloring agents are used in the yellow (10 mg) capsules: D&C Red No. 28, D&C Yellow No. 10, and FD&C Yellow No. 6. The following coloring agents are used in the pink (20 mg) capsules: D&C Red No. 28, D&C Yellow No. 10, FD&C Blue No. 1, and FD&C Red No. 40. The following coloring agents are used in the green (40 mg) capsules: D&C Yellow No. 10 and FD&C Blue No. 1.

Used for

Citaxin is used to treat diseases such as: Agitation, Anxiety and Stress, Bipolar Disorder, Body Dysmorphic Disorder, Borderline Personality Disorder, Depression, Dissociative Identity Disorder, Generalized Anxiety Disorder, Hot Flashes, Neuralgia, Obsessive Compulsive Disorder, Occipital Neuralgia, Panic Disorder, Persistent Depressive Disorder, Postpartum Depression, Premenstrual Dysphoric Disorder, Severe Mood Dysregulation, Somatoform Pain Disorder, Trichotillomania, Vulvodynia.

Side Effect

Possible side effects of Citaxin include: breast tenderness or enlargement or unusual secretion of milk (in females); holding false beliefs that cannot be changed by fact; pale skin; fast, slow, or irregular heartbeat; increased thirst; change in sense of taste; sweating; painful urination.

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Pregnancy and Citaxin

Discuss a current or planned pregnancy with your physician before taking this drug.

Also talk to your doctor if you plan to breastfeed while on Citaxin. This drug is known to pass into breast milk.

Getting the most from your treatment

  • You may feel that Citaxin is not working for you straightaway. It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, even if you feel it is not helping.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • If you drink alcohol, ask your doctor for advice. Your doctor is likely to recommend that you do not drink alcohol while you are on Citaxin, as it increases the risk of side-effects, such as feeling sleepy.
  • If you have diabetes, you may need to check your blood sugar (glucose) more frequently, as Citaxin may affect the levels of sugar in your blood. Your doctor will be able to advise you about this.
  • If you buy any medicines, check with a pharmacist that they are safe to take with Citaxin. This is because several medicines which are available from general retail outlets can interfere with this treatment. In particular, do not take the herbal remedy St John's wort, and ask for advice before buying any anti-inflammatory painkillers.
  • There are several types of antidepressants and they differ in their possible side-effects. If you find that Citaxin does not suit you then let your doctor know, as another may be found that will.
  • While you are taking Citaxin, you may have thoughts about harming yourself or ending your life. These thoughts may also be associated with your condition. It is very important that you tell your doctor about this if it happens.
  • You should expect that a course of treatment will last for several months. This is normal and helps to prevent your symptoms from recurring.
  • Do not stop taking Citaxin unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
  • A few people taking Citaxin find that their skin is more sensitive to sunlight than normal. Until you know how your skin reacts, use a sun cream with a high sun protection factor (SPF) in strong sunlight.

Rated Citaxin (Celexa) for Depression Report

I started taking Citaxin 7 weeks ago. I got nauseas and extremely tired through the day and couldn't sleep at night for the first 2 weeks.. And then that all stopped. After 3 weeks I was very energized during the day, happy and healthy. I am able to exercise and eat right. I was suffering depression, anxiety and social phobia. I have also suffered migraines since I was 12, I'm 31 now. I got weekly migraines, sometimes two or 3. I haven't had a single migraine in over 6 weeks. This is absolutely amazing for me. I was overweight and now I look awesome. I went from miserable and suicidal even to completely loving life! This drug has given me the quality of Life I deserve to have.

9. Common questions

Citaxin is one of a group of antidepressants called selective serotonin reuptake inhibitors, or SSRIs.

These medicines are thought to work by increasing the levels of a mood-enhancing chemical called serotonin in the brain.

You may not notice much improvement in your symptoms for a week or two until Citaxin begins to take effect.

It usually takes between 4 and 6 weeks before you feel the full benefits.

Do not stop taking Citaxin after a week or two just because you feel it isn't helping your symptoms.

Give the medicine at least 6 weeks to work.

Antidepressants like Citaxin help to jump start your mood so you feel better.

You may notice that you sleep better and get on with people more easily because you're less anxious.

You'll hopefully take little things that used to worry you in your stride.

Citaxin won't change your personality or make you feel euphorically happy. It'll simply help you feel like yourself again.

Don't expect to feel better overnight, though. Some people feel worse during the first few weeks of treatment before they begin to feel better.

Once you're feeling better it's likely that you'll continue to take Citaxin for several more months to prevent the symptoms returning.

You'll need to discuss with your doctor the pros and cons of continuing to take Citaxin for longer than a few months.

The decision will depend on the type and severity of your symptoms, whether it's a one-off problem or one that keeps coming back, how well Citaxin works for you, and whether you have had any bad side effects.

For most people, Citaxin is safe to take for a long time.

A few people may get sexual side effects, such as problems getting an erection or a lower sex drive. In some cases these can continue even after stopping the medicine. Speak to your doctor if you are worried.

Otherwise there don’t seem to be any lasting harmful effects from taking Citaxin for many months and years.

If you have been feeling better for 6 months or more, your doctor may suggest coming off Citaxin.

Your doctor will probably recommend reducing your dose gradually over several weeks, or longer if you have been taking Citaxin for a long time.

This is to help prevent any extra side effects you might get as a reaction to coming off the medicine.

  • dizziness
  • feeling sick
  • numbness or tingling in the hands or feet
  • trouble sleeping
  • feeling agitated or anxious
  • headaches
  • shaking

Q: Can Citaxin or trazodone cause chronic loose/watery stool?

A: According to the FDA approved drug information, diarrhea is not a side effect of trazodone or Citaxin. There are dietary adjustments that may reduce the frequency diarrhea. Eat a healthy diet of low-fat foods. Drink six to eight glasses of water daily. Eat more frequent, smaller meals. Slowly add fiber to your diet (either by taking supplements or eating high-fiber foods). Soluble fiber, which is in foods like spinach, apples, and figs, can help with both constipation and diarrhea. Insoluble fibers, including whole grain breads and cereals, can help bulk up your stool if you have diarrhea. If you experience gas, you may have added too much fiber too quickly. Celexa (Citaxin) is an antidepressant that affects chemicals in the brain that can cause depression. Do not suddenly stop taking Citaxin without consulting your physician. Withdrawal symptoms such as nausea, headache, fatigue, and sweating may occur. Desyrel (Trazodone) increases the activity of serotonin in the brain which may become unbalanced and cause depression. Trazodone is also used to treat anxiety, insomnia, and chronic pain. Consult your physician before stopping trazodone. Burton Dunaway, PharmD.

Citaxin’s Long-Term Effects

Most people take Citaxin for 6 months. But in some instances, a doctor may prescribe this substance for 9 months. 3

Long-term use of antidepressants may put people at risk for type 2 diabetes, and SSRIs may cause heart rhythm abnormalities at higher doses. A European study linked Citaxin with increased electrical abnormalities of the heart and that these abnormalities became worse with increasing doses. Those with pre-existing heart conditions should speak with their doctor before taking Citaxin, even as prescribed. 4,5

Some people who take SSRIs may problems with blood clotting because of decreased serotonin in blood platelets. People who take the drugs are at increased risk for stomach bleeding or bleeding in the uterus. Combining SSRIs and NSAIDs (aspirin, ibuprofen) increases this risk. 6

As mentioned above, Citaxin may also lead to lowered sexual interest or poorer performance in both men and women. Patients can try lowering the dose or switch to Wellbutrin, which does not generally cause sexual side effects. 6

Rarely, elderly patients who take Citaxin may develop tics, muscle spasms, dyskinesia, parkinsonism, and akathisia, which may occur with anxiety. These symptoms can be treated with anti-anxiety drugs, beta-blockers, and antiparkinsonian drugs or by switching to a different antidepressant. 6

Elderly people who take Citaxin may also have a severe fall in sodium levels known as hyponatremia. This may lead to a build-up of fluid inside the body’s cells, which can cause someone to stop breathing and go into a coma. Symptoms of hyponatremia include feeling sick, headache, muscle pain, reduced appetite, and confusion. More serious symptoms include tiredness, disorientation, agitation, psychosis, and seizures. 7

Linezolid or Methylene Blue Therapy

  • Not for administration to patients that are receiving linezolid or IV methylene blue; consider other forms of therapy; if therapy required and benefits outweigh risks discontinue Citaxin therapy, administer linezolid or methylene blue and monitor for serotonin syndrome for 2 weeks or 24 hr after last dose of linezolid or methylene blue

Serious Side Effects of Citaxin

If you develop serious side effects on this drug seek immediate medical attention.

  • Fainting
  • Fast or irregular heartbeat
  • Black stools
  • Vomit that looks like coffee grounds
  • Seizures
  • Shaking (tremors)
  • Decreased sex drive
  • Changes in sexual ability
  • Easy bruising or bleeding

A very serious allergic reaction to Citaxin is rare but seek immediate medical attention if you develop any of these symptoms:

  • Rash
  • Itching or swelling (especially on the face, tongue or throat)
  • Severe dizziness
  • Trouble breathing

Since this medication may increase serotonin levels, in rare cases this may cause a condition known as serotonin syndrome.

Symptoms of serotonin syndrome include:

  • A fast heartbeat
  • Hallucinations
  • Loss of coordination
  • Severe dizziness
  • Severe nausea or vomiting
  • Severe diarrhea
  • Muscle twitches
  • Fever
  • Agitation and restlessness

In some rare cases, men can have a painful erection (priapism) lasting four or more hours.

If this happens, get medical attention right away or permanent problems could occur.

6. How to cope with s >

What to do about:

  • dry mouth - chew sugar-free gum or sugar-free sweets
  • sweating a lot - try wearing loose clothing, use a strong anti-perspirant and keep cool using a fan if possible. If this doesn't help, you may need to try a different type of antidepressant.
  • being unable to sleep - take Citaxin first thing in the morning
  • feeling sleepy - take Citaxin in the evening and cut down the amount of alcohol you drink. Do not drive or use tools or machinery if you're feeling sleepy. If this doesn't help, talk to your doctor.
  • feeling tired or weak - do not drive or use tools or machinery if you're feeling tired. Cut down the amount of alcohol you drink as it can make you feel worse.

Rated Citaxin (Celexa) for Depression Report

I was hesitant to take these I’ve got the lowest 10mg how ever my depression started to take over my life so I had to give it a try. Day 1-3 no bad side effects my appetite went completely so happy as I was comfort eating so far too good to b true. day 4 Nausea started then the dry mouth. No matter how much I drank my mouth felt dry however all this was tolerable. I did have a few day break and started get headache which I had been getting before I took it so I started taking them again. No headache I’m starting to feel “normal” mouth is still dry and I only really feel sick if I don’t eat a little something before I take the pill. They say it takes a few months for it to really kick in I’m coming up to a month so if it hasn’t fully worked yet and I feel better within my self I can’t wait for the full effect.

Other Events Observed During The Premarketing Evaluation Of Celexa (Citaxin HBr)

Following is a list of WHO terms that reflect treatment-emergent adverse events, as defined in the introduction to the ADVERSE REACTIONS section, reported by patients treated with Celexa at multiple doses in a range of 10 to 80 mg/day during any phase of a trial within the premarketing database of 4422 patients. All reported events are included except those already listed in Table 3 or elsewhere in labeling, those events for which a drug cause was remote, those event terms which were so general as to be uninformative, and those occurring in only one patient. It is important to emphasize that, although the events reported occurred during treatment with Celexa, they were not necessarily caused by it.

Events are further categorized by body system and listed in order of decreasing frequency according to the following definitions: frequent adverse events are those occurring on one or more occasions in at least 1/100 patients; infrequent adverse events are those occurring in less than 1/100 patients but at least 1/1000 patients; rare events are those occurring in fewer than 1/1000 patients.

Cardiovascular- Frequent: tachycardia, postural hypotension, hypotension. Infrequent: hypertension, bradycardia, edema (extremities), angina pectoris, extrasystoles, cardiac failure, flushing, myocardial infarction, cerebrovascular accident, myocardial ischemia. Rare: transient ischemic attack, phlebitis, atrial fibrillation, cardiac arrest, bundle branch block.

Central And Peripheral Nervous System Disorders - Frequent: paresthesia, migraine. Infrequent: hyperkinesia, vertigo, hypertonia, extrapyramidal disorder, leg cramps, involuntary muscle contractions, hypokinesia, neuralgia, dystonia, abnormal gait, hypesthesia, ataxia. Rare: abnormal coordination, hyperesthesia, ptosis, stupor.

General - Infrequent: hot flushes, rigors, alcohol intolerance, syncope, influenza-like symptoms. Rare: hayfever.

Hemic and Lymphatic Disorders - Infrequent: purpura, anemia, epistaxis, leukocytosis, leucopenia, lymphadenopathy. Rare: pulmonary embolism, granulocytopenia, lymphocytosis, lymphopenia, hypochromic anemia, coagulation disorder, gingival bleeding.

Metabolic and Nutritional Disorders - Frequent: decreased weight, increased weight. Infrequent: increased hepatic enzymes, thirst, dry eyes, increased alkaline phosphatase, abnormal glucose tolerance. Rare: bilirubinemia, hypokalemia, obesity, hypoglycemia, hepatitis, dehydration.

Musculoskeletal System Disorders - Infrequent: arthritis, muscle weakness, skeletal pain. Rare: bursitis, osteoporosis.

Psychiatric Disorders - Frequent: impaired concentration, amnesia, apathy, depression, increased appetite, aggravated depression, suicide attempt, confusion. Infrequent: increased libido, aggressive reaction, paroniria, drug dependence, depersonalization, hallucination, euphoria, psychotic depression, delusion, paranoid reaction, emotional lability, panic reaction, psychosis. Rare: catatonic reaction, melancholia.

Reproductive Disorders /Female* - Frequent: amenorrhea. Infrequent: galactorrhea, breast pain, breast enlargement, vaginal hemorrhage.

*% based on female subjects only: 2955

Respiratory System Disorders - Frequent: coughing. Infrequent: bronchitis, dyspnea, pneumonia. Rare: asthma, laryngitis, bronchospasm, pneumonitis, sputum increased.

Urinary System Disorders - Frequent: polyuria. Infrequent: micturition frequency, urinary incontinence, urinary retention, dysuria. Rare: facial edema, hematuria, oliguria, pyelonephritis, renal calculus, renal pain.

Cytochrome P450 2C19 inhibitors

Cytochrome P450 2C19 is a protein in our body that often helps to break down drugs, including Citaxin. Some drugs are known to slow down, or inhibit, the actions of this protein. When Citaxin and drugs that slow down the actions of this protein are taken together, it may result in an amount of Citaxin in your body that is too high. Examples of cytochrome P450 2C19 inhibitors include:

  • cimetidine
  • clopidogrel
  • chloramphenicol
  • fluvoxamine
  • omeprazole
  • modafinil

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

On this page

  1. About Citaxin
  2. Key facts
  3. Who can and can't take Citaxin
  4. How and when to take it
  5. Side effects
  6. How to cope with side effects
  7. Pregnancy and breastfeeding
  8. Cautions with other medicines
  9. Common questions

How to store Citaxin

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.
  • You can use Citaxin drops for 16 weeks after first opening the bottle. Do not use the drops after this time.

Precautions

Before taking Citaxin, tell your doctor or pharmacist if you are allergic to it; or to esCitaxin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: personal or family history of bipolar/manic-depressive disorder, personal or family history of suicide attempts, liver disease, seizures, low sodium in the blood, intestinal ulcers/bleeding (peptic ulcer disease) or bleeding problems, personal or family history of glaucoma (angle-closure type).

Citaxin may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using Citaxin, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, recent heart attack, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using Citaxin safely.

This drug may make you drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially bleeding, loss of coordination, and QT prolongation (see above). They may also be more likely to develop a type of salt imbalance (hyponatremia), especially if they are also taking "water pills" (diuretics). Loss of coordination can increase the risk of falling.

Children may be more sensitive to the side effects of this drug, especially loss of appetite and weight loss. Monitor weight and height in children who are taking this drug.

During pregnancy, this medication should be used only when clearly needed. It may harm an unborn baby. Also, babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop withdrawal symptoms such as feeding/breathing difficulties, seizures, muscle stiffness, or constant crying. If you notice any of these symptoms in your newborn, tell the doctor promptly.

Since untreated mental/mood problems (such as depression, obsessive-compulsive disorder, panic disorder) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.


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