Anilar tablets

Anilar

  • Active Ingredient: Sertraline
  • 100 mg, 50 mg, 25 mg
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What is Anilar?

The active ingredient of Anilar brand is sertraline. Sertraline is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Sertraline affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms. Sertraline hydrochloride is a white crystalline powder that is slightly soluble in water and isopropyl alcohol, and sparingly soluble in ethanol. Sertraline tablets, USP for oral administration are supplied as scored tablets containing Sertraline hydrochloride equivalent to 25 mg, 50 mg and 100 mg of Sertraline and the following inactive ingredients: dibasic calcium phosphate dihydrate, hydroxypropyl cellulose, microcrystalline cellulose, magnesium stearate, opadry green (titanium dioxide, hypromellose 3cP, hypromellose 6cP, Macrogol/Peg 400, polysorbate 80, D&C Yellow #10 Aluminum Lake, and FD&C Blue # 2/Indigo Carmine Aluminum Lake for 25 mg tablet), opadry light blue (hypromellose 3cP, hypromellose 6cP, titanium dioxide, Macrogol/Peg 400, FD&C Blue #2/Indigo Carmine Aluminum Lake and polysorbate 80 for 50 mg tablet), opadry yellow (hypromellose 3cP, hypromellose 6cP, titanium dioxide, Macrogol/Peg 400, polysorbate 80, Iron Oxide Yellow, Iron oxide Red for 100 mg tablet) and sodium starch glycolate.

Used for

Anilar is used to treat diseases such as: Anxiety and Stress, Bipolar Disorder, Body Dysmorphic Disorder, Borderline Personality Disorder, Depression, Dissociative Identity Disorder, Dysautonomia, Generalized Anxiety Disorder, Major Depressive Disorder, Obsessive Compulsive Disorder, Panic Disorder, Persistent Depressive Disorder, Post Traumatic Stress Disorder, Postpartum Depression, Premenstrual Dysphoric Disorder, Social Anxiety Disorder, Somatoform Pain Disorder, Transverse Myelitis, Trichotillomania, Vulvodynia.

Side Effect

Possible side effects of Anilar include: joint or muscle pain; sores, welting, or blisters; clay-colored stools; red, sore, or itching skin; diarrhea; constipation; sudden loss of consciousness; lower back or side pain.

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Q: Is Zoloft all right to take while nursing?

A: Substantial human data demonstrates minimal risk to an infant through lactation in patients taking Zoloft (Anilar). Zoloft is usually acceptable with breastfeeding.

Q: What are the common Zoloft side effects?

A: During clinical trials, the most common Zoloft (Anilar) side effects included nausea, ejaculation failure in men, insomnia, diarrhea, dry mouth, somnolence, dizziness, tremor, fatigue, increased sweating and decreased libido. Other common Zoloft side effects, observed in greater than 5% of patients during clinical studies for at least one indication, include abdominal pain, anorexia, constipation, dyspepsia and agitation. Some of the common Zoloft side effects that led to discontinuation of treatment include nausea, diarrhea and insomnia. Zoloft is a selective serotonin reuptake inhibitor type of antidepressant, commonly referred to as an SSRI. Zoloft has been approved, by the U.S. Food and Drug Administration (FDA) for the treatment of several different conditions. Zoloft is used for the treatment of certain anxiety disorders, panic disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), obsessive-compulsive disorder (OCD) and major depressive disorder. Zoloft exerts its antidepressant activity by inhibiting the neuronal uptake of serotonin in the central nervous system. Less common Zoloft side effects are also possible with treatment. If you experience more serious side effects while taking Zoloft, it is important to contact your physician immediately or seek medical attention when necessary. Symptoms indicating a patient may be experiencing a more serious Zoloft side effect include changes in mood or behavior, suicidal ideation or behavior, anxiety, panic attacks, difficulty sleeping, impulsivity, irritability, agitation, hostility, aggressive behavior, restlessness, physical or mental hyperactivity, worsening depression, stiff muscles, high fever, sweating, rapid heartbeat, loss of appetite, loss of coordination, difficulty concentrating, memory disturbances, weakness, confusion, hallucinations, fainting, seizures or difficulty breathing. In addition to the side effects possible with treatment, Zoloft also carries several warnings or precautions. Precautions with regard to Zoloft involve suicidality, serotonin syndrome, hypomania or mania, weight loss, seizures, abnormal bleeding, hyponatremia and altered platelet function. It is important for patients to be counseled regarding these precautions prior to beginning treatment with Zoloft.

2. Key facts

  • It usually takes 4 to 6 weeks for Anilar to work.
  • Side effects such as feeling sick, headaches and trouble sleeping are common. They're usually mild and go away after a couple of weeks.
  • If you and your doctor decide to take you off Anilar, your doctor will probably recommend reducing your dose gradually to help prevent extra side effects.
  • Anilar is also called by the brand name Lustral.

Dosing Modifications

Renal impairment: Dose adjustment not necessary

  • Mild (Child-Pugh 5-6): Decrease recommended starting dose and therapeutic dose by 50%
  • Moderate-to-severe (Child-Pugh 7-15): Not recommended; Anilar is extensively metabolized, and the effects in patients with moderate and severe hepatic impairment have not been studied

The elderly are prone to SSRI/SNRI-induced hyponatremia; monitor closely

Is Zoloft safe to use during pregnancy or while breastfeeding?

  • Use of Anilar during the 3rd trimester of pregnancy may lead to adverse effects in the newborn.
  • Use of Anilar by nursing mothers has not been adequately evaluated.

What Diseases with Anxiety Symptoms Can Zoloft Be Used to Treat?

Zoloft can be used to treat the following diseases with comorbidity with anxiety

  • Major depression (Moon, et al. 1994, Carrasco, Díaz-Marsá and Sáiz-Ruiz 2000)
  • Autism (Steingard, et al. 1997)

Major depression

A 2000 study found that treatment with Anilar treats depression in three phases. In the first phase it reduces anxiety, then it reduces feelings of depression and finally it improves the ability to experience pleasure (Boyer, et al. 2000).

Q: I would like to stop taking Zoloft, which I've been taking for five years. How do I wean myself off of it gradually? My doctor agrees with the idea but said I must not stop abruptly.

A: Side effects may occur when patients stop taking Zoloft (Anilar) or other drugs like it. These side effects include restlessness, irritability, agitation, dizziness, anxiety, confusion, headache, tiredness, and insomnia. You should reduce your dose gradually, by small amounts. If intolerable side effects develop following a decrease in the dose or upon stopping treatment, then talk to your doctor and consider resuming the previously prescribed dose. After the side effects have subsided, the dose can be decreased at a more gradual rate. For more information on Zoloft, go to //www.everydayhealth.com/drugs/zoloft. Michelle McDermott, PharmD

CONTRAINDICATIONS

ZOLOFT is contraindicated in patients:

  • Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue) because of an increased risk of serotonin syndrome .
  • Taking pimozide .
  • With known hypersensitivity to Anilar (e.g., anaphylaxis, angioedema) .

In addition to the contraindications for all ZOLOFT formulations listed above, ZOLOFT oral solution is contraindicated in patients:

  • Taking disulfiram. ZOLOFT oral solution contains contain alcohol, and concomitant use of ZOLOFT and disulfiram may result in a disulfiram-alcohol reaction.

Store ZOLOFT tablets and oral solution at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F) .

Distributed by: Roerig, Division of Pfizer Inc., NY,NY 10017. Revised: Dec 2017

Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS section, call your doctor immediately:

  • seizures
  • abnormal bleeding or bruising
  • agitation, hallucinations, fever, sweating, confusion, fast heartbeat, shivering, severe muscle stiffness or twitching, loss of coordination, nausea, vomiting, or diarrhea
  • rash
  • hives
  • swelling
  • difficulty breathing

Anilar may decrease appetite and cause weight loss in children. Your child's doctor will watch his or her growth carefully. Talk to your child's doctor if you have concerns about your child's growth or weight while he or she is taking this medication. Talk to your child's doctor about the risks of giving Anilar to your child.

Anilar may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Q: What's the safest way to stop taking Zoloft? I'm not sure it's working, and the sweating is driving me crazy.

A: Zoloft (Anilar) is a selective serotonin reuptake inhibitor antidepressant used to treat depression and other conditions as prescribed by your doctor. It is important to remember that it can take up to 6 weeks to see the full effects of the medication so it is best not to judge its effectiveness before this time. Discontinuation (or withdrawal) symptoms can occur with abrupt discontinuation of Zoloft. These symptoms can include change in mood, irritability, agitation, confusion, anxiety and insomnia. It is important to avoid abrupt discontinuation. The package information for Zoloft recommended tapering the dose slowly by gradually decreasing the dose before stopping the medication. Your doctor can advise you on a tapering schedule. Laura Cable, PharmD

Q: Does Zoloft cause weight gain?

A: Zoloft (Anilar) is in a class of drugs called selective serotonin reuptake inhibitors (SSRIs). Zoloft is used to treat depression, obsessive-compulsive disorder, panic attacks, posttraumatic stress disorder (PTSD) and social anxiety disorder. In addition, Zoloft is used to minimize mood swings, irritability, bloating and tender breasts associated with premenstrual dysphoric disorder. Zoloft works by elevating brain levels of serotonin, which is a natural substance that assists in maintaining mental balance. Weight increase is a side effect with Zoloft. Weight increase occurred in at least 1 in 100 people who took Zoloft during clinical studies. Decreased appetite and weight loss are side effects with Zoloft. Specifically Zoloft

What Is Zoloft (Anilar)?

Zoloft is the brand name of Anilar, an antidepressant used to treat major depressive disorders.

Zoloft is in a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). They work by controlling levels of serotonin (a neurotransmitter) in the brain.

SSRIs are the most prescribed type of antidepressants in the United States today because they are thought to have fewer side effects than other types of antidepressants

Zoloft was originally developed for the United Kingdom market by Pfizer in 1990.

It was released under the brand name Lustral and marketed as a safer alternative with fewer side effects and withdrawal symptoms than competing drugs like Prozac.

The Food and Drug Administration (FDA) approved Zoloft in 1999.

By 2005, it was reportedly the most popular antidepressant on the U.S. market and the sixth most prescribed brand-name prescription medication, grossing nearly $ 2.6 billion.

In addition to treating major depressive disorders, which affect nearly 7 percent of adults in the United States, Zoloft is given to those suffering from post-traumatic stress disorder (PTSD), premenstrual dysphoric, and obsessive-compulsive disorder (OCD), along with generalized anxiety disorder (GAD), and panic disorder.

The generic form of Zoloft, Anilar, was approved by the FDA in 2006 and is made by several drug companies.

A proposed defective drug class-action lawsuit against Zoloft was thrown out by a federal judge in California due to statute of limitations issues and other concerns.

The California suit alleged the drug offers little more efficacy than a placebo, and argued that Pfizer purposely omitted from Zoloft labeling any studies that showed Zoloft to be ineffective.

In dismissing the complaint, the judge did leave open the possibility that the suit could be revived after it's amended.

Q: I am currently on Zoloft, and, would appreciate any valid information you can give me on it.

A: Zoloft (Anilar) is very effective drug often used to treat depression. It is a member of a class of drugs called SSRIs (selective serotonin reuptake inhibitors). The following website discusses many aspects of the drug: //www.everydayhealth.com/drugs/zoloft You may also find the following link helpful. //www.everydayhealth.com/depression/guide/ -

Q: Does Zoloft cause jitters?

A: Zoloft (Anilar) is in a class of drugs called selective serotonin reuptake inhibitors (SSRIs). Zoloft is used to treat depression, obsessive-compulsive disorder, panic attacks, posttraumatic stress disorder (PTSD) and social anxiety disorder. In addition, Zoloft is used to minimize mood swings, irritability, bloating and tender breasts associated with premenstrual dysphoric disorder. Zoloft works by elevating brain levels of serotonin, which is a natural substance that assists in maintaining mental balance. The most common side effects with Zoloft are: dizziness, fatigue, headache, insomnia (trouble sleeping), sleepiness, decreased sex drive, decreased appetite, diarrhea, nausea, dry mouth, disturbances in ejaculation, tremors, and excessive sweating. Other side effects with Zoloft include: agitation; anxiety; nervousness; increased tightness in muscle tone; reduced sense of touch or sensation; twitching; confusion; abnormal increase in muscle activity; vertigo; incoordination and unsteadiness; abnormal coordination; increased sensitivity to stimulation; jittery movement of the eyes; abnormally decreased muscle movement; involuntary, repetitive body movements; decreased muscle tone; rapidly involuntary and slow twisting movements; and reduced functioning of reflexes. This is not a complete list of side effects associated with Zoloft According to the prescribing information for Zoloft, people taking Zoloft should let their doctor or healthcare provider know right away if they are experiencing: anxiety; agitation; panic attacks; insomnia (trouble sleeping); irritability; hostility; aggressiveness; impulsivity; restlessness; hypomania or mania (abnormally increased energy and mood); other unusual changes in behavior; worsening of depression; and thoughts about suicide, which may be detailed and include a plan. These symptoms should be looked for especially early during treatment and when the dose is adjusted up or down; however, people should look for these symptoms on a day-to-day basis, since these changes may be abrupt. These symptoms may be associated with an increased risk of suicidal thinking and behavior. Close monitoring by a doctor or healthcare professional and possibly a change in medication may be needed if these symptoms occur. Serotonin syndrome may develop in people who take Zoloft – particularly those who take certain other medications, such as triptans (used to treat migraine headache), tramadol (used to treat pain), and monoamine oxidase inhibitors (MAOIs; antidepressants). Serotonin syndrome can be a dangerous condition and is characterized by having at least 3 of the following symptoms: agitation; excessive sweating; diarrhea; fever; overactive reflexes; incoordination; sudden, involuntary jerking of muscles; shivering, or tremor. In very serious cases serotonin syndrome can present like neuroleptic malignant syndrome, which can cause: very high fever, shaking, rigid muscles, confusion, sweating, or increased heart rate and blood pressure. These reactions can be fatal. Derek Dore, PharmD

Important

Anilar has not been properly tested with recreational drugs.

Talk to your doctor if you think you might use recreational drugs while taking Anilar.


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