Q: Is it safe to take Allegron if you have COPD?
A: Allegron (Pamelor) is in a class of medications known as tricyclic antidepressants. Allegron is indicated to treat the symptoms of depression. Allegron works by affecting some of the natural chemicals in the brain that are associated with mood and mental balance. Allegron is sometimes used for other conditions including smoking cessation, panic disorders, and post-herpetic neuralgia (pain that lingers after a shingles infection). However, Allegron is not approved by the U.S. Food and Drug Administration for these uses. Some of the side effects associated with Allegron include nausea, vomiting, diarrhea, drowsiness, dry mouth, tinnitus, dizziness, and weakness. There was no warning or precaution listed in the prescribing information in regards to Allegron use in people with chronic obstructive pulmonary disease (COPD). Only your health care provider can determine which treatments may be safe for you. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Kristen Dore, PharmD
By Julie Marks | Medically Reviewed by Ruthan White, PharmD
Latest Update: 2014-10-27 Copyright © 2014 Everyday Health Media, LLC
Usual Adult Dose
25 mg three or four times daily; dosage should begin at a low level and be increased as required. As an alternative regimen, the total daily dosage may be given once a day. When doses above 100 mg daily are administered, plasma levels of Allegron should be monitored and maintained in the optimum range of 50 to 150 ng/mL. Doses above 150 mg/day are not recommended.
Rated Allegron (Pamelor) for Neuropathic Pain Report
I reluctantly took this medication because I’ve never found that antidepressant type drugs were worth the side effects. My physician was very persistent. I’ve had recurrent shingles since I was 20 and I am now 47 and I have PHN nerve damage due to all the outbreaks. I also have a slipped disk pushing on said nerve. Friggin ouch, hurts all the time. Insomnia and pain running down my left leg that feels like a constant current of electrocution. Long story short on a very low-dose 10 mg of Allegron I noticed about 20% pain relief the next day. I’ve been on the medication for about two months and now I have about a 30% reduction of pain. A bonus side effect is that my periods are not nearly as painful and also I don’t have to urinate as much as I used to. Negatives are dry mouth and in the beginning Worse insomnia. I highly recommend This drug for shingles related nerve pain.
Rated Allegron (Pamelor) for Depression Report
I've been taking Allegron in a 50mg dose for about 10 months. The main reason for my taking it is to help with the pretty severe insomnia I've had for over 25 years but couldn't treat or even admit to because of my job. When I first started taking it, it was consistently effective but after a while I guess I developed a tolerance to it where it now isn't as consistently effective. For a few months now I seem to go in streaks where for a week or two I'll revert back to my old ways of virtually no sleep, but then I'll go back to a period of getting pretty good sleep. The main side effects I've experienced are the dry mouth and throat, occasional dizziness on standing up quickly and occasional afternoon tiredness. All of these side effects have lessened over time and are quite tolerable. Even though the help with my insomnia isn't as consistent as I could wish, it is still a great help and I'm thankful for it. The benefits easily out weigh the side effects. If anyone is considering taking this drug for serious insomnia, I would recommend it.
The elimination half life of Allegron is between 16 and 90 hours.
It takes 5.5 elimination half life's for a drug to be cleared from ones system. So it could take a maximum of 495 hours i.e. 8.25 days (5.5 x 90 hours) for Allegron to be cleared from ones body.
Marvell, I know this comment is old, but if you see this, can you tell me where you heard that it takes 5.5 half life's for a drug to be cleared from your system? I've never heard this and thought it was interesting.
Q: Is Allegron used to treat Meniere's disease (an inner ear disturbance)?
A: Pamelor (Allegron) belongs to a group of drugs called tricyclic antidepressants. Allegron affects chemicals in the brain that may be unbalanced. Allegron is indicated for depression. Medicines are sometimes prescribed for conditions that are not mentioned in the patient leaflet and/or prescribing information. Do not use Allegron for a condition for which it was not prescribed. If you would like more information, talk with your doctor. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Kimberly Hotz, PharmD
Q: Does Allegron cause weight gain?
A: Allegron is a medication that is used to treat depression. It is in the class of medications called tricyclic antidepressants and works by keeping certain chemicals active in the brain (when levels get low cause depression symptoms) to relieve your symptoms. This medication is also used for chronic pain, anxiety, fibromyalgia among other conditions. The prescribing information on Allegron lists the following as common side effects of the medication: dizziness, drowsiness, confusion, constipation, dry mouth, weight loss or gain, and increased sweating. Weight gain and weight loss were seen in equal numbers during clinical studies of the medication but the occurrence was rare and it is unknown if the medication is the cause of the issue. For more information on Allegron, click on this link: //www.everydayhealth.com/drugs/Allegron If you think that the medication you are taking is causing weight gain, consult with your physician. Do not stop or alter the dose of the medication without first talking to your provider. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Lori Poulin, PharmD
How to use Allegron HCL
Read the Medication Guide provided by your pharmacist before you start taking Allegron and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth, usually 1 to 4 times daily or as directed by your doctor. If you are using the liquid form, measure the dose carefully using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects (such as dry mouth, dizziness), your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.
Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.
It is important to continue taking this medication even if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Also, you may experience symptoms such as mood swings, headache, tiredness, and sleep change. To prevent these symptoms while you are stopping treatment with this drug, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details. Report any new or worsening symptoms right away.
This medication may not work right away. You may see some benefit within a week. However, it may take up to 4 weeks before you feel the full effect.
Tell your doctor if your condition persists or worsens (such as your feelings of sadness get worse, or you have thoughts of suicide).
Why is this medication prescribed?
Allegron is used to treat depression. Allegron is in a group of medications called tricyclic antidepressants. It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance.
Alcohol interaction warning
The use of drinks that contain alcohol together with Allegron can lead to suicidal thoughts and attempts. This risk is higher if you have a history of suicidal thoughts and trouble controlling your emotions. If you drink alcohol, talk to your doctor.