Liprimar tablets

Liprimar

  • Active Ingredient: Atorvastatin
  • 40 mg, 20 mg, 10 mg, 5 mg
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What is Liprimar?

The active ingredient of Liprimar brand is atorvastatin. Atorvastatin is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Atorvastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL). Atorvastatin calcium is a white to off-white colored powder free from visible extraneous matter. Atorvastatin calcium is soluble in dimethyl sulphoxide, slightly soluble in alcohol, very slightly soluble in water, in pH 7.4 phosphate buffer and in acetonitrile and practically insoluble in aqueous solutions of pH 4 and below. Atorvastatin calcium tablets for oral administration contain 10, 20, 40, or 80 mg Atorvastatin and the following inactive ingredients: anhydrous lactose, NF; colloidal silicon dioxide, NF; copovidone, NF; croscarmellose sodium, NF; magnesium stearate, NF; mannitol, USP; silicified microcrystalline cellulose, NF; sodium bicarbonate, USP; sodium carbonate anhydrous, NF; sodium lauryl sulfate, NF; lecitihin, polyvinyl alcohol part hydrolyzed, talc, titanium dioxide, xanthan gum.

Used for

Liprimar is used to treat diseases such as: High Cholesterol, High Cholesterol, Familial Heterozygous, High Cholesterol, Familial Homozygous, Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa, Elevated LDL, Hyperlipoproteinemia Type IIb, Elevated LDL VLDL, Hyperlipoproteinemia Type III, Elevated beta-VLDL IDL, Hyperlipoproteinemia Type IV, Elevated VLDL, Prevention of Cardiovascular Disease, Rheumatoid Arthritis.

Side Effect

Possible side effects of Liprimar include: fast heartbeat; fruit-like breath odor; shivering; sweating; chills.

How to Buy Liprimar tablets online?

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home drugs a-z list Lipitor(Liprimar Calcium) side effects drug center

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Lipitor (Liprimar) is a statin used for the treatment of elevated total cholesterol, LDL, triglycerides, and to elevate HDL cholesterol. Side effects of Lipitor include:

Contact your doctor if you experience serious side effects of Lipitor including:

The recommended dose of Lipitor is 10-80 mg daily. Erythromycin (E-Mycin), ketoconazole (Nizoral), itraconazole (Sporanox), cyclosporine (Sandimmune), indinavir (Crixivan) and ritonavir (Norvir) decrease elimination of Lipitor. Lipitor increases the effect of warfarin (Coumadin) and cholestyramine (Questran) decreases the absorption of Lipitor. Lipitor should not be taken during pregnancy because the developing fetus requires cholesterol for development, and Lipitor reduces the production of cholesterol. Lipitor passes into breast milk and could harm a nursing baby. Breastfeeding while taking Lipitor is not recommended.

Our Lipitor Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should this medicine be used?

Liprimar comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take Liprimar at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Liprimar exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may start you on a low dose of Liprimar and gradually increase your dose, not more than once every 2 to 4 weeks.

Continue to take Liprimar even if you feel well. Do not stop taking Liprimar without talking to your doctor.

What should I discuss with my healthcare provider before taking Liprimar (Lipitor)?

You should not use Liprimar if you are allergic to it, or if you have:

This medicine can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Stop taking Liprimar and tell your doctor right away if you become pregnant Use effective birth control to prevent pregnancy while you are taking this medicine.

Do not breast-feed while you are taking Liprimar.

Tell your doctor if you have ever had:

  • liver problems;
  • muscle pain or weakness;
  • kidney disease;
  • diabetes;
  • a thyroid disorder; or
  • if you drink more than 2 alcoholic beverages daily.

Liprimar can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

Liprimar is not approved for use by anyone younger than 10 years old.

4. How and when to take it

Take Liprimar once a day. You can choose to take it at any time, as long as you stick to the same time every day.

Sometimes doctors may recommend taking it in the evening. This is because your body makes most cholesterol at night. If you're not sure when to take your medicine, ask a pharmacist or your doctor for advice.

Liprimar doesn't upset the stomach, so you can take it with or without food.

Swallow Liprimar tablets whole with a glass of water. If you've been given chewable tablets, you can chew them or swallow them whole with a glass of water.

Why it’s used

Liprimar is used to improve cholesterol levels in people with different types of cholesterol problems. It’s also used to decrease your risk for heart attack and stroke. It’s used together with diet, weight loss, and exercise.

Liprimar helps to prevent cholesterol from building up in your arteries. Clogged arteries can block blood flow to your heart and brain.

Liprimar may be used as part of a combination therapy. This means you may need to take it with other medications. These may include bile acid resins and other cholesterol-lowering medications.

Side Effects

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very small number of people taking Liprimar may have mild memory problems or confusion. If these rare effects occur, talk to your doctor.

Rarely, statins may cause or worsen diabetes. Talk to your doctor about the benefits and risks.

This drug may rarely cause muscle problems (which can rarely lead to very serious conditions called rhabdomyolysis and autoimmune myopathy). Tell your doctor right away if you develop any of these symptoms during treatment and if these symptoms persist after your doctor stops this drug: muscle pain/tenderness/weakness (especially with fever or unusual tiredness), signs of kidney problems (such as change in the amount of urine).

This medication may rarely cause liver problems. If you notice any of the following rare but serious side effects, tell your doctor right away: yellowing eyes/skin, dark urine, severe stomach/abdominal pain, persistent nausea/vomiting.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

What is the most important information I should know about Liprimar (Lipitor)?

You should not take Liprimar if you are pregnant or breast-feeding, or if you have liver disease.

Stop taking this medication and tell your doctor right away if you become pregnant.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Liprimar can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark urine.

What is the dosage for Lipitor (Liprimar)? How should it be taken?

  • Lipitor is prescribed once daily.
  • The usual starting dose for adults is 10-20 mg per day, and the maximum dose is 80 mg per day. Adults who need more than a 45% reduction in LDL cholesterol may be started at 40 mg daily.
  • Pediatric patients should receive 10 mg once daily up to a maximum dose of 20 mg daily.
  • Lipitor may be taken with or without food and at any time of day.

What is Lipitor (Liprimar)? How does it work (mechanism of action)?

Lipitor (Liprimar) is type of statin that lowers the level of cholesterol in the blood. All statins, including Liprimar, prevent the production of cholesterol in the liver by blocking HMG-CoA reductase, an enzyme that makes cholesterol. Statins reduce total cholesterol as well as LDL cholesterol in blood. LDL cholesterol is believed to be the "bad" cholesterol that is primarily responsible for the development of coronary artery disease. Reducing LDL cholesterol levels retards progression and may even reverse coronary artery disease. Liprimar also raises the concentrations of HDL ("good") cholesterol that protects against coronary artery disease and reduces the concentration of triglycerides in the blood. (High blood concentrations of triglycerides also have been associated with coronary artery disease.)

Examples of other statins include:

The FDA approved Liprimar in December 1996.

Liprimar

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Liprimar, marketed under the trade name Lipitor among others, is a member of the drug class known as statins, which are used primarily as a lipid-lowering agent and for prevention of events associated with cardiovascular disease.

Warnings for other groups

For pregnant women: Liprimar should never be used during pregnancy. Safety in pregnant women is unknown and there’s no apparent benefit of this drug during pregnancy.

Call your doctor right away if you become pregnant while taking this drug.

For women who are breastfeeding: Liprimar should not be used during breastfeeding. If you breastfeed your child, talk to your doctor about what medication could be right for you.

For seniors: People over the age of 65 years have a higher risk for muscle breakdown (rhabdomyolysis) while taking Liprimar.

For children: Liprimar hasn’t been studied and shouldn’t be used in children younger than 10 years. This drug has been shown to be safe and effective in children 10–17 years of age.

This dosage information is for Liprimar oral tablet. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

Where can I get more information (Lipitor)?

Your pharmacist can provide more information about Liprimar.

Important information

You should not take Liprimar if you are pregnant or breast-feeding, or if you have liver disease.

Stop taking this medication and tell your doctor right away if you become pregnant.

Serious drug interactions can occur when certain medicines are used together with Liprimar. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.

In rare cases, Liprimar can cause a condition that results in the breakdown of skeletal muscle tissue, potentially leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Avoid eating foods that are high in fat or cholesterol. Liprimar will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Liprimar is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Summary

Lipitor (Liprimar) is a drug in the statin drug classed prescribed to patients to lower blood cholesterol, LDL, and triglycerides, elevate HDL cholesterol, to prevent angina, stroke, heart attack, congestive heart failure, revascularization procedures in heart disease, and prevent heart attacks, and strokes in patients with type 2 diabetes. Side effects of Lipitor include headache, urinary tract infections (UTIs), joint pain, common cold, intestinal gas (flatulence), diarrhea, constipation, and heartburn.

Drug interactions, dosing, and pregnancy and breastfeeding safety should be reviewed prior to taking any medication.

What are the side effects of Lipitor (Liprimar)?

Lipitor is generally well tolerated. Minor side effects include:

Other commonly reported side effects include:

Lipitor may cause liver and muscle damage. Serious liver damage caused by statins is rare. Liver tests should be performed at the beginning of treatment then as needed thereafter.

Inflammation of the muscles caused by statins can lead to serious breakdown of muscle cells called rhabdomyolysis. Rhabdomyolysis causes the release of muscle protein (myoglobin) into the blood, and myoglobin can cause kidney failure and even death. When used alone, statins cause rhabdomyolysis in less than one percent of patients. To prevent the development of serious rhabdomyolysis, patients taking Liprimar should contact their health-care professional immediately if they develop unexplained muscle pain, weakness, or muscle tenderness.

Statins have been associated with increases in HbA1c and fasting serum glucose levels as seen in diabetes.

Post-marketing reports for Liprimar of adverse events include:

Symptoms may start one day to years after starting treatment and resolve within a median of three weeks after stopping the statin.


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