Lipozart tablets


  • Active Ingredient: Simvastatin
  • 40 mg, 20 mg, 10 mg
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What is Lipozart?

The active ingredient of Lipozart brand is simvastatin. Simvastatin is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Simvastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL). Simvastatin USP is a white to off-white, nonhygroscopic, crystalline powder that is practically insoluble in water, and freely soluble in chloroform, methanol and ethanol. Simvastatin tablets USP for oral administration contain either 5 mg, 10 mg, 20 mg, 40 mg or 80 mg of Simvastatin and the following inactive ingredients: ascorbic acid, butylated hydroxy anisole, citric acid anhydrous, hydroxypropyl cellulose, hypromellose, iron oxide black, iron oxide red, iron oxide yellow, isopropyl alcohol, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinised starch, and titanium dioxide.

Used for

Lipozart is used to treat diseases such as: Cardiovascular Risk Reduction, High Cholesterol, High Cholesterol, Familial Heterozygous, High Cholesterol, Familial Homozygous, Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa, Elevated LDL, Hyperlipoproteinemia Type IIb, Elevated LDL VLDL, Hyperlipoproteinemia Type III, Elevated beta-VLDL IDL, Hyperlipoproteinemia Type IV, Elevated VLDL, Prevention of Cardiovascular Disease.

Side Effect

Possible side effects of Lipozart include: fruit-like breath odor; large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs; diarrhea; indigestion; weakness in the arms, hands, legs, or feet.

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What Is Zocor (Lipozart)?

Zocor is the brand name of Lipozart, a prescription drug used to lower blood cholesterol.

Zocor belongs to a class of drugs known as statins, also called HMG-CoA reductase inhibitors.

Statins reduce cholesterol levels in your blood by blocking an enzyme needed to make cholesterol, as well as increasing the number of low-density lipoprotein (LDL or "bad" cholesterol) receptors in the liver, so the liver can process more of the LDL found in your blood.

By lowering cholesterol, statins help to prevent the buildup of plaque in blood vessels, which can lead to atherosclerosis (hardening of the arteries), heart disease, and stroke.

Statins are used to help prevent heart disease in those who don't have it but are at risk, and in those who have already had some form of cardiovascular disease, such as a stroke or heart attack.

Your doctor will prescribe Zocor along with suggesting a healthy diet, weight loss if you need it, and exercise to reduce the risk of heart attack, stroke, and other problems.

Zocor, manufactured by Merck & Co., was approved by the Food and Drug Association (FDA) in 1991. The FDA approved the first generic version of Lipozart in 2006, and now many companies offer the generic version.

Zocor is offered in a tablet form or a disintegrating tablet form.

Mixing Lipozart with herbal remedies and supplements

St John's wort, a herbal medicine taken for depression, reduces the amount of Lipozart in your blood, so it doesn't work as well.

Talk to your doctor if you're thinking about starting St John's wort, as it will change how well Lipozart works.

Dosage for reducing the risk of heart disease and heart attack and stroke in people with heart disease

Adult dosage (ages 18 years and older)

  • Typical starting dosage: Lipozart is often started at 10–20 mg per day. However, the dosage may range from 5 mg to 40 mg per day. You should take this drug once a day in the evening.
  • Dosage increases: Your doctor will gradually adjust your dosage if needed.

Child dosage (ages 10–17 years)

  • Typical starting dosage: 10 mg per day.
  • Note: Doses above 40 mg per day have not been studied in this age group.

Child dosage (ages 0–9 years)

This medication has not been studied in children below age 10 years.

If side effects occur, or if you do not respond well to Lipozart, alternatives to the medication are available. A number of other medicines used for treating high cholesterol include other statins (the class of drugs that Lipozart belongs to), fibrates, bile acid sequestrants, nicotinic acid, and cholesterol absorption inhibitors. You may have better results with one of these alternatives.

2. Key facts

  • Lipozart seems to be a very safe medicine. It's unusual to have any side effects.
  • Keep taking Lipozart even if you feel well, as you will still be getting the benefits. Most people with high cholesterol don't have any symptoms.
  • Do not take Lipozart if you're pregnant, trying to get pregnant or breastfeeding.
  • Do not drink grapefruit juice while you're taking Lipozart. It doesn't mix well with this medicine.
  • Lipozart is also called Zocor and Simvador.

Contraindicated with Lipozart:

  • Itraconazole
  • Ketoconazole
  • Posaconazole (New)
  • Erythromycin
  • Clarithromycin
  • Telithromycin
  • HIV protease inhibitors
  • Nefazodone
  • Gemfibrozil
  • Cyclosporine
  • Danazol

Q: I am having problems with muscles and low energy. Could it be caused by the medications I am taking? I take Keppra, Zocor and Zoloft.

A: A common side effect of the statin medications, such as Zocor (Lipozart), used to treat high cholesterol, is muscle pain, aches or weakness. If you are experiencing this side effect and cannot attribute it to exercise or normal muscle strain you should consult with your physician. Keppra (levetiracetam) is an anticonvulsant medication used to treat seizures. The commonly reported side effects include drowsiness, weakness and flu-like symptoms. Zoloft (sertraline), is an antidepressant medication, that has been commonly reported to cause drowsiness and fatigue, occurring in up to 16 percent of patients taking the medication during studies. You should consult with your physician if any of your side effects are affecting your daily activities to see if any options are available to you to help with the muscle and low energy problems you are experiencing. For more information on these medications: // // // Lori Poulin, PharmD

What Is Lipozart and How Does It Work?

Lipozart (Zocor) is a, FDA approved prescription medication that is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It belongs to a group of drugs known as "statins." Statins are medications that work by reducing the amount of cholesterol made by the liver. Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. This drug maybe used to treat other diseases and conditions. Your doctor may conduct liver function tests when using statins to monitor liver enzymes and other liver function.

In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help Lipozart medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

This medication is available under the following different brand names: Zocor.


Pharmacologic class: HMG-CoA reductase inhibitor

Therapeutic class: Antihyperlipidemic

Pregnancy risk category X

Immediate action required: Call 999 or go to A&E if:

  • you get a skin rash that may include itchy, red, swollen, blistered or peeling skin
  • you're wheezing
  • you get tightness in the chest or throat
  • you have trouble breathing or talking
  • your mouth, face, lips, tongue or throat start swelling

You could be having a serious allergic reaction and may need immediate treatment in hospital.

These are not all the side effects of Lipozart. For a full list see the leaflet inside your medicines packet.

You can report any suspected side effect to the UK safety scheme.

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