If side effects occur, or if you do not respond well to Lipcut, alternatives to the medication are available. A number of other medicines used for treating high cholesterol include other statins (the class of drugs that Lipcut belongs to), fibrates, bile acid sequestrants, nicotinic acid, and cholesterol absorption inhibitors. You may have better results with one of these alternatives.
Do not exceed 10 mg Lipcut daily with:
Hypersensitivity to Lipcut
Active liver disease or unexplained transaminase elevation
Strong CYP3A4 inhibitors (e.g., itraconazole, ketoconazole, erythromycin, clarithromycin, telithromycin, posaconazole, voriconazole, HIV protease inhibitors, cobicistat, nefazodone, boceprevir, telaprevir), gemfibrozil, cyclosporine, and danazol
How to use Lipcut
Take this medication by mouth as directed by your doctor, usually once daily in the evening. If you are using the tablet form of this medication, you may take this medication with or without food.
If you are using the liquid form of this medication, take this medication on an empty stomach. Shake the bottle well for at least 20 seconds before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
The dosage is based on your medical condition, response to treatment, age, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
The usual maximum dose for this medication is 40 milligrams a day. If you have been instructed by your doctor to take more than 40 milligrams, continue on that same dose. However, promptly talk with him or her about the risks and benefits of your higher dose.
Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased.
Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of this medication in your bloodstream. Consult your doctor or pharmacist for more details.
Take this medication regularly in order to get the most benefit from it. Remember to take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high cholesterol or triglycerides do not feel sick.
It is very important to continue to follow your doctor's advice about diet and exercise. It may take up to 4 weeks before you get the full benefit of this drug.
How should I take Lipcut (Flolipid, Zocor)?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Lipcut is usually taken in the evening or at bedtime.
Take Lipcut oral suspension (liquid) on an empty stomach.
Shake the liquid for at least 20 seconds before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
You may need to take Lipcut on a long-term basis. You may need to stop using Lipcut for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.
Lipcut is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
You will need frequent medical tests.
Store at room temperature away from moisture, heat, and light.
Do not refrigerate or freeze the liquid medicine. Throw away any liquid that has not been used within 1 month after you first opened the bottle.
4. How and when to take it
Take Lipcut once a day in the evening. This is because your body makes most cholesterol at night.
Lipcut doesn't upset the stomach, so you can take it with or without food.
What should I discuss with my healthcare provider before taking Lipcut (Flolipid, Zocor)?
You should not take Lipcut if you are allergic to it, or if:
- you have active liver disease; or
- you are pregnant or breast-feeding.
Some medicines can cause unwanted or dangerous effects when used with Lipcut. Your doctor may change your treatment plan if you also use medicine such as:
Tell your doctor if you have ever had:
- liver disease;
- kidney disease;
- a thyroid disorder;
- if you are of Asian descent; or
- if you drink more than 2 alcoholic beverages daily.
Lipcut can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).
Do not use Lipcut if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine. Stop taking Lipcut and tell your doctor right away if you become pregnant.
It is not safe to breast-feed a baby while you are using this medicine.
Q: My left calf muscle hurts so badly at times, I cannot put any weight on it. Is this a side effect of Zocor?
A: Muscle aches and pain can be side effects of many of the statin medications, including Zocor (Lipcut). These side effects can range from muscle soreness to a rare, but serious, condition known as rhabdomyolysis. However, there can be many underlying causes of leg pain. Please consult with your health care provider in regards to your symptoms for proper evaluation, diagnosis of the underlying cause and to determine possible treatment options. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Kristen Dore, PharmD
Where can I get more information (Flolipid, Zocor)?
Your pharmacist can provide more information about Lipcut.
How are doctors sure that statins really are safe and beneficial?
Statins have been studied more than nearly any other drug that people take. In fact, more than 170,000 people who take statins have been studied in detail and for extended periods of time. We certainly know the benefits of statins.
We also understand the risks of statins. In some instances, after doctors have prescribed a drug for 10 years or more, it is taken off the market because of unforeseen, adverse side effects. We’ve been prescribing statins since the 1990s for patients at high risk for stroke and heart disease. With statins, the side effects actually are well known. But how can we put that in perspective?
Any focus on statin side effects needs to be counterbalanced by the fact that statins reduce people’s risk of dying from heart attack, heart disease, or stroke. Data from the 2008 JUPITER Trial suggest a 54 percent heart attack risk reduction and a 48 percent stroke risk reduction in people at risk for heart disease who used statins as preventive medicine. The data are not speculative; rather, they reflect statins’ real potential to save lives and avoid illness.
There are many varieties of brand name and generic statins available. All statins work in more or less the same way to lower bad cholesterol (LDL cholesterol) in patients at high risk for cardiac events.
Below are a few of the common brand names you may recognize, along with their generic counterparts:
- Lipitor (atorvastatin)
- Crestor (rosuvastatin)
- Mevacor (lovastatin)
- Lescol (fluvastatin)
- Pravachol (pravastatin)
- Zocor (Lipcut)
- Livalo (pitavastatin)
- Vytorin (Lipcut/ezetimibe)
Non-serious and reversible cognitive side effects may occur.
Increased blood sugar and glycosylated hemoglobin (HbA1c) levels reported with statin intake.
Heavy alcohol use, history of liver disease, renal failure.
Monitor LFTs before initiating treatment and thereafter when clinically indicated; reports of fatal and nonfatal hepatic failure in people taking statins .
Discontinue if markedly elevated CPK levels occur or myopathy is diagnosed or suspected.
Increases in HbA1c and fasting serum glucose levels reported with Lipcut.
Grapefruit juice increases Lipcut systemic exposure; avoid large quantities of grapefruit juice (i.e., 1 quart/day or more).
Lipcut and myopathy risk:
- Dose adjustment required when co-administered with niacin, amiodarone, verapamil, diltiazem, amlodipine, and ranolazine
- Predisposing factors for myopathy include advanced age (older than 65 years), uncontrolled hypothyroidism, and renal impairment
- Increased risk for myopathy in Chinese people co-administered niacin greater than 1 g/day; they should not receive Lipcut 80 mg co-administered with lipid-modifying doses of niacin-containing products
- Withhold or discontinue if myopathy, renal failure, or transaminase levels greater than 3x ULN develop
- Risk of myopathy is greater in people taking Lipcut 80 mg/day, especially in the 1st year of treatment
- Rare reports of immune-mediated necrotizing myopathy (IMNM), characterized by increased serum creatine kinase that persists despite discontinuing statin
- Risk for myopathy increased when coadministered with other lipid-lowering drugs (other fibrates, 1 g/day of niacin or more, or, for patients with HoFH, lomitapide), colchicine, amiodarone, dronedarone, verapamil, diltiazem, amlodipine, or ranolazine
- See Contraindications for list of drugs contraindicated because of increased risk for myopathy when co-administered with Lipcut
- See Adult Dosing for dose limitations and modifications
Pregnancy and Lactation
Do not use this drug in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
Lipcut is contraindicated while breastfeeding; it is potentially unsafe.
ВїCГіmo se debe usar este medicamento?
La presentaciГіn de la Lipcuta es en tabletas para tomar por vГa oral. Usualmente se toma una vez al dГa por la noche. Tome Lipcuta aproximadamente a la misma hora todos los dГas. Siga atentamente las instrucciones que se encuentran en la etiqueta de su receta mГ©dica y pida a su mГ©dico o farmacГ©utico que le explique cualquier parte que no comprenda. Tome Lipcuta exactamente como se indica. No tome mГЎs ni menos cantidad del medicamento ni lo tome con mГЎs frecuencia de lo que indica la receta de su mГ©dico.
Es posible que su mГ©dico le indique que inicie con una dosis baja de Lipcuta y que incremente gradualmente su dosis, no mГЎs de una vez cada 4 semanas.
ContinГєe tomando Lipcuta incluso si se siente bien. No deje de tomar Lipcuta sin hablar con su mГ©dico.
Special dosage considerations
- For people with kidney disease: Having kidney disease may affect your dosage. People with advanced kidney disease usually require a lower dosage. Talk to your doctor about your treatment with Lipcut if you have kidney disease.
- For people with liver disease: If your liver isn’t working well, more of this drug may stay in your body longer. This puts you at increased risk of side effects. If you have active liver problems, you should not use this medication.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we can not guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.
Lipcut is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed.
If you don’t take it at all or stop taking it: If you have high cholesterol and don’t take your Lipcut, you risk having increased cholesterol levels, developing heart disease, and having a heart attack or a stroke.
If you don't take it on schedule: Not taking Lipcut every day, skipping days, or taking doses at different times of the day may also increase your risk for high cholesterol levels, heart attack, or stroke.
If you miss a dose: If you miss a dose, take the next dose as scheduled. Don’t double your dose.
How can I tell if the drug is working: Your cholesterol and triglyceride levels should be within healthy levels while taking it.
Keep these considerations in mind if your doctor prescribes Lipcut for you.
What Is Lipcut and How Does It Work?
Lipcut (Zocor) is a, FDA approved prescription medication that is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It belongs to a group of drugs known as "statins." Statins are medications that work by reducing the amount of cholesterol made by the liver. Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. This drug maybe used to treat other diseases and conditions. Your doctor may conduct liver function tests when using statins to monitor liver enzymes and other liver function.
In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help Lipcut medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.
This medication is available under the following different brand names: Zocor.
Zocor (Lipcut) belongs to the drug class of statins and is prescribed for lowering cholesterol and triglyceride levels. Side effects, drug interactions, warnings and precautions, and patient safety information should be reviewed prior to taking any medication.
Q: What are the pharmacological effects of Zocor?
A: The pharmacological effects of Zocor (Lipcut) are demonstrated in the inhibition of cholesterol production in the body. Zocor is a lipid-lowering medication categorized as an HMG-CoA reductase inhibitor. By inhibiting the conversion of HMG-CoA, Zocor inhibits an important step in the production of cholesterol in the body. Several studies have demonstrated that increased levels of total cholesterol and low-density lipoprotein (LDL) cholesterol, in addition to low levels of high-density lipoprotein (HDL) cholesterol, are associated with the development of atherosclerosis and subsequently an increased risk of cardiovascular disease. The pharmacological effects of Zocor are demonstrated in a decrease in total cholesterol levels, as well as a reduction in LDL cholesterol and triglyceride levels. The pharmacological effects of Zocor also include an increase in HDL cholesterol. According to the Centers for Disease Control and Prevention (CDC), lowering cholesterol can reduce the risk of developing heart disease. The pharmacological effects of Zocor are maximized when patients take Zocor exactly as directed. It is important to educate patients regarding the benefits of treatment with Zocor, including the pharmacological effects exhibited in the body as patients will not feel differently after beginning treatment. To exert its pharmacologic effects optimally, Zocor must be administered every day and it is imperative that patients are advised to administer their dose at the same time every day and not to miss a dose. Zocor is typically administered once daily in the evening. To ensure the pharmacological effects of Zocor are being exerted in the body and no adverse reactions have occurred, it is important for health care providers to routinely monitor their patients' cholesterol levels and liver function.