Lifibrat tablets

Lifibrat

  • Active Ingredient: Fenofibrate
  • 160 mg
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What is Lifibrat?

The active ingredient of Lifibrat brand is fenofibrate. Fenofibrate helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).

Used for

Lifibrat is used to treat diseases such as: Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa, Elevated LDL, Hyperlipoproteinemia Type IIb, Elevated LDL VLDL, Hyperlipoproteinemia Type IV, Elevated VLDL, Hyperlipoproteinemia Type V, Elevated Chylomicrons VLDL, Hypertriglyceridemia.

Side Effect

Possible side effects of Lifibrat include: unusual tiredness; troubled breathing; eye irritation; pains in the stomach, side, or abdomen, possibly radiating to the back; muscle cramps, pain, stiffness, swelling, or weakness; bloody urine; yellow eyes or skin.

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Q: Does Lifibrat initially cause an increase in daily bowel movements and/or gas?

A: Lifibrat is a medication used for cholesterol. Studies suggest that Lifibrat initially can cause diarrhea, constipation, nausea and stomach discomfort. As your body gets used to the medication, these side effects might subside. If it is intolerable or extremely bothersome, please contact your physician to rule our other conditions. it is important to take medications exactly as prescribed by your physician. More information about Lifibrat can be found at //www.everydayhealth.com/drugs/Lifibrat

Rated Lifibrat for Hyperlipoproteinemia Type IIa (Elevated LDL) Report

For me this stuff was very bad,10 days in I had severe tiredness,rash on my knuckles and elbow, felt like i was losing strength,and could not function clearly,pounding headache,just not for me,so I tossed this stuff into the trash

Description

What is this drug used for?

It is used to lower triglycerides.It is used to lower bad cholesterol and raise good cholesterol (HDL).

Pharmacy Lifibrat 145mg Tablet

Lifibrat | Global Pharmaceuticals, Division Of Impax Laboratories Inc.

The initial treatment for dyslipidemia is dietary therapy specific for the type of lipoprotein abnormality. Excess body weight and excess alcoholic intake may be important factors in hypertriglyceridemia and should be addressed prior to any drug therapy. Physical exercise can be an important ancillary measure. Diseases contributory to hyperlipidemia, such as hypothyroidism or diabetes mellitus should be looked for and adequately treated. Estrogen therapy, thiazide diuretics and beta-blockers, are sometimes associated with massive rises in plasma triglycerides, especially in subjects with familial hypertriglyceridemia. In such cases, discontinuation of the specific etiologic agent may obviate the need for specific drug therapy of hypertriglyceridemia.

Lipid levels should be monitored periodically and consideration should be given to reducing the dosage of Lifibrat tablets if lipid levels fall significantly below the targeted range.

Therapy should be withdrawn in patients who do not have an adequate response after two months of treatment with the maximum recommended dose of 120 mg once daily.

2.2 Primary Hypercholesterolemia or Mixed Dyslip >The initial dose of Lifibrat tablets is 120 mg per day.

2.3 Severe Hypertriglycer >The initial dose is 40 to 120 mg per day. Dosage should be individualized according to patient response, and should be adjusted if necessary following repeat lipid determinations at 4 to 8 week intervals. The maximum dose is 120 mg per day.

2.4 Impaired Renal Function

Treatment with Lifibrat tablets should be initiated at a dose of 40 mg per day in patients with mild to moderately impaired renal function, and increased only after evaluation of the effects on renal function and lipid levels at this dose. The use of Lifibrat tablets should be avoided in patients with severe renal impairment .

2.5 Geriatric Patients

Dose selection for the elderly should be made on the basis of renal function .

Lifibrat dosing information

Usual Adult Dose of Lifibrat for Hyperlipoproteinemia Type IIa (Elevated LDL):

Tricor: 145 mg orally once a day. Lofibra and others: 160 mg to 200 mg orally once a day with food. Antara: 130 mg orally once a day. Triglide: 160 mg orally once a day. Lipofen: 150 mg orally once a day with food. Fenoglide: 120 mg orally once a day with food.

Usual Adult Dose for Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL):

Tricor: 145 mg orally once a day. Lofibra and others: 160 mg to 200 mg orally once a day with food. Antara: 130 mg orally once a day. Triglide: 160 mg orally once a day. Lipofen: 150 mg orally once a day with food. Fenoglide: 120 mg orally once a day with food.

Usual Adult Dose of Lifibrat for Hyperlipoproteinemia Type IV (Elevated VLDL):

Tricor: 48 to 145 mg orally once a day. Lofibra and others: 54 mg to 200 mg orally once a day with food. Antara: 43 mg to 130 mg orally once a day. Triglide: 50 mg to 160 mg orally once a day. Lipofen: 50 mg to 150 mg orally once a day with food. Fenoglide: 40 mg to 120 mg orally once a day with food.

Usual Adult Dose for Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL):

Tricor: 48 to 145 mg orally once a day. Lofibra and others: 54 mg to 200 mg orally once a day with food. Antara: 43 mg to 130 mg orally once a day. Triglide: 50 mg to 160 mg orally once a day. Lipofen: 50 mg to 150 mg orally once a day with food. Fenoglide: 40 mg to 120 mg orally once a day with food.

Usual Geriatric Dose of Lifibrat for Hyperlipoproteinemia:

Tricor: 48 mg orally once a day. Increases in dosage should occur only after evaluating the effects on renal function and lipid levels at this dose, with a maximum recommended dose of 145 mg/24 hours.

Lofibra and others: 54 mg to 67 mg orally once a day with food. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.

Antara: 43 mg orally once a day. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.

Triglide: 50 mg orally once a day. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.

Lipofen: 50 mg orally once a day with food. Individualize dosage according to patient response and adjust if necessary following repeat lipid determinations at 4 to 8 week intervals.

Fenoglide: 40 mg to 120 mg orally once a day with food

Which drugs or supplements interact with Lifibrat?

Fibric acid derivatives may increase the adverse effects of colchicine (Colcrys) on muscle tissue.

Cyclosporine may increase the toxic effects of fibric acid derivatives on the kidney while fibric acid derivatives may decrease blood levels of cyclosporine.

Lifibrat and its derivatives may increase the adverse effects associated with ezetimibe (Zetia), HMG-CoA reductase inhibitors (statins), and sulfonlyureas. Fibric acid derivatives may increase the anticoagulation (blood-thinning) benefits of warfarin (Coumadin).

Warnings

  • This medication contains Lifibrat. Do not take Tricor, Lofibra tablets, Fenoglide, Lipofen, and Triglide if you are allergic to Lifibrat or any ingredients contained in this drug
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately

Lifibrat (Tricor) Dosage

The brand Tricor is available in strengths of 54 milligrams (mg) and 160 mg. Generic Lifibrat is available in 48 mg and 154 mg tablets. You should not take more than the highest dose prescribed by your doctor in one day.

Always take Lifibrat with a full glass of water regardless of whether you eat. Eating may delay Lifibrat’s effect.

How to use Lifibrat

Take this medication by mouth as directed by your doctor, usually once daily. Lifibrat comes in different types of capsules and tablets which provide different amounts of the medication. Do not switch between different forms or brands of this medication unless directed by your doctor. Some forms of this drug should be taken with food but others may be taken with or without food. Ask your pharmacist about your brand of Lifibrat. It is important to take this medication correctly so that the drug has the greatest benefit.

The dosage is based on your medical condition and response to treatment.

If you are also taking certain other drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take Lifibrat at least 1 hour before or at least 4 to 6 hours after taking these medications. These medications can bind to Lifibrat, preventing your body from fully absorbing the drug.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not increase your dose or use this drug more often or for longer than prescribed. Your cholesterol/triglycerides level will not lower faster, and your risk of side effects will increase. It is important to continue taking this medication even if you feel well. Most people with high cholesterol/triglycerides do not feel sick.

It is very important to continue to follow your doctor's advice about diet and exercise. It may take up to 2 months before you get the full benefit of this medication.

Lifibrat side effects

Get emergency medical help if you have signs of an allergic reaction to Lifibrat (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

In rare cases, Lifibrat can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark colored urine.

Also call your doctor at once if you have:

sharp stomach pain spreading to your back or shoulder blade;

loss of appetite, stomach pain just after eating a meal;

jaundice (yellowing of the skin or eyes);

fever, chills, weakness, sore throat, mouth sores, unusual bruising or bleeding;

chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or

swelling, warmth, or redness in an arm or leg.

Common Lifibrat side effects may include:

abnormal laboratory tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings for other groups

For pregnant women: There haven’t been enough studies done in humans to show if Lifibrat poses a risk to a human fetus. Research in animals has shown a risk to the fetus when the mother takes the drug. However, animal studies don’t always predict the way humans would respond.

Talk with your doctor if you’re pregnant or planning to become pregnant. This drug should be used only if the potential benefit justifies the potential risk.

If you become pregnant while taking this drug, call your doctor right away.

For women who are breastfeeding: Lifibrat may pass into breast milk and cause side effects in a child who is breastfed. Talk with your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

Lifibrat oral tablet is used for long-term treatment. It comes with risks if you don’t take it as prescribed.

If you stop taking the drug suddenly or don’t take it at all: Your cholesterol levels may not be controlled. This raises your risk of serious health problems such as heart disease, heart attack, or stroke.

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:

  • headache
  • back pain
  • nausea
  • muscle pain
  • diarrhea
  • common cold
  • upper respiratory tract infection

If you think you’ve taken too much of the drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room.

What to do if you miss a dose: Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working: Your cholesterol levels should improve. You won’t feel Lifibrat working, but your doctor will check your cholesterol levels using blood tests. Your doctor may adjust your dosage based on the results of these tests.

Keep these considerations in mind if your doctor prescribes Lifibrat for you.

Pregnancy

Limited available data with Lifibrat use in pregnant women are insufficient to determine a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes


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