Hafenthyl capsules

Hafenthyl

  • Active Ingredient: Fenofibrate
  • 160 mg
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What is Hafenthyl?

The active ingredient of Hafenthyl brand is fenofibrate. Fenofibrate helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).

Used for

Hafenthyl is used to treat diseases such as: Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa, Elevated LDL, Hyperlipoproteinemia Type IIb, Elevated LDL VLDL, Hyperlipoproteinemia Type IV, Elevated VLDL, Hyperlipoproteinemia Type V, Elevated Chylomicrons VLDL, Hypertriglyceridemia.

Side Effect

Possible side effects of Hafenthyl include: muscle aches and pains; upper right abdominal or stomach pain; nausea or vomiting; yellow eyes or skin; unusual bleeding or bruising.

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Hafenthyl products should be stored at room temperature, between 15 C to 30 C (59 F to 86 F).

Other Information

Hafenthyl tablets, is a lipid regulating agent available as tablets for oral administration. Each tablet contains 40 mg or 120 mg Hafenthyl. The chemical name for Hafenthyl is 2--2-methyl-propanoic acid, 1-methylethyl ester with the following structural formula:

What is Hafenthyl?

Hafenthyl belongs to a group of drugs known as "fibrates." It helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).

Hafenthyl is used along with a proper diet to help to treat high cholesterol and high triglyceride levels.

In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help Hafenthyl work better include exercising, losing weight if overweight, and stopping smoking.

Hafenthyl and Other Interactions

You should avoid taking cholesterol-lowering drugs known as statins, such asrosuvastatin, (Crestor), atorvastatin (Lipitor), simvastatin (Zocor), lovastatin (Mevacor), and others.

If you are taking statins while on Hafenthyl, it can increase your risk of having a reaction that damages your muscles and kidneys.

Also, talk to your doctor before taking Hafenthyl if you are taking ezetimibe (Zetia).

Hafenthyl can increase the effects of blood-thinning medications.

You should not take Hafenthyl while on any of the following drugs:

  • Colchicine (Colcrys)
  • Telbivudine (Tybexa)
  • Ursodiol (Actigall)
  • Contraceptives and hormone replacement medications containing: conjugated estrogens, estradiol, estropipate, ethinyl estradiol, or mestranol
  • Water or flu >Back to Top

Liver damage warning

Hafenthyl can cause abnormal results in tests of liver function. These abnormal results can indicate liver damage. This drug can also cause other liver damage and inflammation after years of use.

Clinical monitoring

Your doctor will monitor your health during your treatment with this drug. They’ll do blood tests to help make sure your cholesterol levels are within the range your doctor feels is best for you. The tests will also tell if your medication is working.

Also, your doctor will likely monitor certain health issues. This can help make sure you stay safe while taking this drug. These issues include:

  • Kidney function. Blood tests can check how well your kidneys are working. If your kidneys aren’t working well, your doctor may lower your dosage of this drug.
  • Liver function. Blood tests can check how well your liver is working. If your tests are abnormal, it may mean that Hafenthyl is causing damage to your liver. Your doctor may switch you to a different medication.
  • Lipid levels. Blood tests can check how well this drug is lowering your cholesterol and triglycerides. Your doctor may change your therapy based upon these results.

What Other Drugs Interact with Hafenthyl?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Severe interactions of Hafenthyl include:

Serious Interactions of Hafenthyl include:

Hafenthyl has moderate interactions with at least 26 different drugs.

Mild Interactions of Hafenthyl include:

This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.

Hafenthyl | Global Pharmaceuticals, Division Of Impax Laboratories Inc.

The initial treatment for dyslipidemia is dietary therapy specific for the type of lipoprotein abnormality. Excess body weight and excess alcoholic intake may be important factors in hypertriglyceridemia and should be addressed prior to any drug therapy. Physical exercise can be an important ancillary measure. Diseases contributory to hyperlipidemia, such as hypothyroidism or diabetes mellitus should be looked for and adequately treated. Estrogen therapy, thiazide diuretics and beta-blockers, are sometimes associated with massive rises in plasma triglycerides, especially in subjects with familial hypertriglyceridemia. In such cases, discontinuation of the specific etiologic agent may obviate the need for specific drug therapy of hypertriglyceridemia.

Lipid levels should be monitored periodically and consideration should be given to reducing the dosage of Hafenthyl tablets if lipid levels fall significantly below the targeted range.

Therapy should be withdrawn in patients who do not have an adequate response after two months of treatment with the maximum recommended dose of 120 mg once daily.

2.2 Primary Hypercholesterolemia or Mixed Dyslip >The initial dose of Hafenthyl tablets is 120 mg per day.

2.3 Severe Hypertriglycer >The initial dose is 40 to 120 mg per day. Dosage should be individualized according to patient response, and should be adjusted if necessary following repeat lipid determinations at 4 to 8 week intervals. The maximum dose is 120 mg per day.

2.4 Impaired Renal Function

Treatment with Hafenthyl tablets should be initiated at a dose of 40 mg per day in patients with mild to moderately impaired renal function, and increased only after evaluation of the effects on renal function and lipid levels at this dose. The use of Hafenthyl tablets should be avoided in patients with severe renal impairment .

2.5 Geriatric Patients

Dose selection for the elderly should be made on the basis of renal function .

What Is Hafenthyl (Tricor)?

Hafenthyl is the generic form of the brand name drug Tricor, used to treat high levels of cholesterol and triglyceride in your blood.

Hafenthyl belongs to a class of medications known as antilipemics and fibric acid. It works by breaking down fats and helping the body eliminate triglycerides.

Tricor was originally approved by the Food and Drug Administration (FDA) in 2001 and is manufactured by Abbott Laboratories.

Hafenthyl is a prescription drug. It comes in two forms: oral tablet and oral capsule.

The oral tablet is available as the brand-name drugs Fenoglide, Tricor, and Triglide. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.

Hafenthyl may be used as part of a combination therapy. This means you may need to take it with other cholesterol drugs, such as statins.

Hafenthyl | Mylan Pharmaceuticals Inc.

Patients should be advised to swallow Hafenthyl capsules whole. Do not open, crush, dissolve or chew capsules.

The initial treatment for dyslipidemia is dietary therapy specific for the type of lipoprotein abnormality. Excess body weight and excess alcoholic intake may be important factors in hypertriglyceridemia and should be addressed prior to any drug therapy. Physical exercise can be an important ancillary measure. Diseases contributory to hyperlipidemia, such as hypothyroidism or diabetes mellitus should be looked for and adequately treated. Estrogen therapy, thiazide diuretics and beta-blockers are sometimes associated with massive rises in plasma triglycerides, especially in subjects with familial hypertriglyceridemia. In such cases, discontinuation of the specific etiologic agent may obviate the need for specific drug therapy of hypertriglyceridemia.

Lipid levels should be monitored periodically and consideration should be given to reducing the dosage of Hafenthyl if lipid levels fall significantly below the targeted range.

Therapy should be withdrawn in patients who do not have an adequate response after 2 months of treatment with the maximum recommended dose of 130 mg once daily.

2.2 Primary Hypercholesterolemia and Mixed Dyslip >The initial dose of Hafenthyl capsules is 130 mg per day.

2.3 Severe Hypertriglycer >The initial dose is 43 mg to 130 mg per day. Dosage should be individualized according to patient response, and should be adjusted if necessary following repeat lipid determinations at 4 to 8 week intervals. The maximum dose is 130 mg per day.

2.4 Impaired Renal Function

Treatment with Hafenthyl capsules should be initiated at a dose of 43 mg per day in patients having mild to moderately impaired renal function, and increased only after evaluation of the effects on renal function and lipid levels at this dose. The use of Hafenthyl capsules should be avoided in patients with severe renal impairment .

2.5 Geriatric Patients

Dose selection for the elderly should be made on the basis of renal function .

What Is Hafenthyl and How Does It Work?

Hafenthyl is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It works by increasing the natural substance (enzyme) that breaks down fats in the blood. Hafenthyl belongs to a group of drugs known as "fibrates." Lowering triglycerides in people with very high triglyceride blood levels may decrease the risk of pancreas disease (pancreatitis). However, Hafenthyl might not lower your risk of a heart attack or stroke. Talk to your doctor about the risks and benefits of Hafenthyl.

In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help Hafenthyl work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

Hafenthyl is available under the following different brand names: Tricor, Lofibra tablets, Fenoglide, Lipofen, and Triglide.

Dosages of Hafenthyl:

Dosage Forms and Strengths

Dosage Considerations – Should be Given as Follows:

Pediatric: Safety and efficacy not established

  • Hypercholesterolemia, mixed dyslipidemia: Initially, 145 mg orally once/day
  • Hypertriglyceridemia: Initially, 48-145 mg orally once/day
  • Titrate every 4-8 weeks up to no more than 145 mg orally once/day
  • Geriatric, initial: 48 mg/day; evaluate before increase dose

  • Hypercholesterolemia, Mixed Dyslipidemia: initial 160 mg orally once/day
  • Hypertriglyceridemia: 50-160 mg orally once/day initially
  • Geriatric, initial: 50 mg/day

  • Hypercholesterolemia, Mixed Dyslipidemia: initial 150 mg orally once/day
  • Hypertriglyceridemia: initial 50-150 mg orally once/day
  • Geriatric, initial: No more than 50 mg/day

  • Hypercholesterolemia, Mixed Dyslipidemia: 160 mg orally once/day
  • Hypertriglyceridemia: 54-160 mg orally once/day
  • Geriatric, initial: 54 mg/day

  • Hypercholesterolemia, Mixed Dyslipidemia: 120 mg orally once/day
  • Hypertriglyceridemia: 40-120 mg orally once/day
  • Geriatric, initial: 40 mg/day

  • Symptoms include GI distress
  • Treatment is supportive

Renal impairment (CrCl less than 50 mL/min):

  • TriCor: Initial, 48 mg/day initially; evaluate before increase dose
  • Triglide: Initial, 50 mg/day
  • Lipofen: Initial, no more than 50 mg/day
  • Lofibra tablets: Initial, 54 mg/day
  • Fenoglide: Initial, 40 mg/day

  • TriCor, Triglide, and Lofibra tablets can be taken without regard to meals
  • Lipofen: Take with meals

Common Side Effects of Hafenthyl

If you have any of the following common side effects of Hafenthyl and they do not go away or become severe, call your doctor or get emergency medical care:

Hafenthyl may actually lower levels of a type of good cholesterol called HDL-C.

Hafenthyl | American Health Packaging

The initial treatment for dyslipidemia is dietary therapy specific for the type of lipoprotein abnormality. Excess body weight and excess alcoholic intake may be important factors in hypertriglyceridemia and should be addressed prior to any drug therapy. Physical exercise can be an important ancillary measure. Diseases contributory to hyperlipidemia, such as hypothyroidism or diabetes mellitus should be looked for and adequately treated. Estrogen therapy, thiazide diuretics and beta-blockers, are sometimes associated with massive rises in plasma triglycerides, especially in subjects with familial hypertriglyceridemia. In such cases, discontinuation of the specific etiologic agent may obviate the need for specific drug therapy of hypertriglyceridemia.

Lipid levels should be monitored periodically and consideration should be given to reducing the dosage of Hafenthyl if lipid levels fall significantly below the targeted range.

Therapy should be withdrawn in patients who do not have an adequate response after two months of treatment with the maximum recommended dose of 145 mg once daily.

2.2 Primary Hypercholesterolemia or Mixed Dyslip >The initial dose of Hafenthyl is 145 mg once daily.

2.3 Severe Hypertriglycer >The initial dose is 48 to 145 mg per day. Dosage should be individualized according to patient response, and should be adjusted if necessary following repeat lipid determinations at 4 to 8 week intervals. The maximum dose is 145 mg once daily.

2.4 Impaired Renal Function

Treatment with Hafenthyl should be initiated at a dose of 48 mg per day in patients having mild to moderately impaired renal function, and increased only after evaluation of the effects on renal function and lipid levels at this dose. The use of Hafenthyl should be avoided in patients with severe renal impairment

2.5 Geriatric Patients

Dose selection for the elderly should be made on the basis of renal function .

Rated Hafenthyl for Hyperlipoproteinemia Report

I haven't been taking it long enough to have had my cholesterol levels re-checked, but have had no side effects other than a slight headache.

Missed Dose of Hafenthyl

If you miss a dose of Hafenthyl, try to take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of the medication at the same time.

Storage

  • Store Fenoglide and Tricor tablets at room temperature between 59°F and 86°F (15°C and 30°C).
  • Store generic Hafenthyl tablets and Triglide tablets between 68°F and 77°F (20°C and 25°C).
  • Don’t store these medications in moist or damp areas, such as bathrooms.
  • Keep Triglide in its moisture-protective container until you’re ready to take it.

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