Cardin tablets


  • Active Ingredient: Simvastatin
  • 40 mg, 20 mg, 10 mg
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What is Cardin?

The active ingredient of Cardin brand is simvastatin. Simvastatin is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Simvastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL). Simvastatin USP is a white to off-white, nonhygroscopic, crystalline powder that is practically insoluble in water, and freely soluble in chloroform, methanol and ethanol. Simvastatin tablets USP for oral administration contain either 5 mg, 10 mg, 20 mg, 40 mg or 80 mg of Simvastatin and the following inactive ingredients: ascorbic acid, butylated hydroxy anisole, citric acid anhydrous, hydroxypropyl cellulose, hypromellose, iron oxide black, iron oxide red, iron oxide yellow, isopropyl alcohol, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinised starch, and titanium dioxide.

Used for

Cardin is used to treat diseases such as: Cardiovascular Risk Reduction, High Cholesterol, High Cholesterol, Familial Heterozygous, High Cholesterol, Familial Homozygous, Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa, Elevated LDL, Hyperlipoproteinemia Type IIb, Elevated LDL VLDL, Hyperlipoproteinemia Type III, Elevated beta-VLDL IDL, Hyperlipoproteinemia Type IV, Elevated VLDL, Prevention of Cardiovascular Disease.

Side Effect

Possible side effects of Cardin include: ear congestion; trouble sleeping; weakness in the arms, hands, legs, or feet; increased thirst; swelling; upper right abdominal or stomach pain; skin rash, encrusted, scaly, and oozing.

How to Buy Cardin tablets online?

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What is the most important information I should know about Cardin (Flolipid, Zocor)?

You should not take Cardin if you are pregnant or breast-feeding, or if you have active liver disease.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Stop taking Cardin and tell your doctor right away if you become pregnant.

What are the possible side effects of Cardin (Flolipid, Zocor)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

In rare cases, Cardin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Also call your doctor at once if you have:

  • liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Non-serious and reversible cognitive side effects may occur.

Increased blood sugar and glycosylated hemoglobin (HbA1c) levels reported with statin intake.

Heavy alcohol use, history of liver disease, renal failure.

Monitor LFTs before initiating treatment and thereafter when clinically indicated; reports of fatal and nonfatal hepatic failure in people taking statins .

Discontinue if markedly elevated CPK levels occur or myopathy is diagnosed or suspected.

Increases in HbA1c and fasting serum glucose levels reported with Cardin.

Grapefruit juice increases Cardin systemic exposure; avoid large quantities of grapefruit juice (i.e., 1 quart/day or more).

Cardin and myopathy risk:

  • Dose adjustment required when co-administered with niacin, amiodarone, verapamil, diltiazem, amlodipine, and ranolazine
  • Predisposing factors for myopathy include advanced age (older than 65 years), uncontrolled hypothyroidism, and renal impairment
  • Increased risk for myopathy in Chinese people co-administered niacin greater than 1 g/day; they should not receive Cardin 80 mg co-administered with lipid-modifying doses of niacin-containing products
  • Withhold or discontinue if myopathy, renal failure, or transaminase levels greater than 3x ULN develop
  • Risk of myopathy is greater in people taking Cardin 80 mg/day, especially in the 1st year of treatment
  • Rare reports of immune-mediated necrotizing myopathy (IMNM), characterized by increased serum creatine kinase that persists despite discontinuing statin
  • Risk for myopathy increased when coadministered with other lipid-lowering drugs (other fibrates, 1 g/day of niacin or more, or, for patients with HoFH, lomitapide), colchicine, amiodarone, dronedarone, verapamil, diltiazem, amlodipine, or ranolazine
  • See Contraindications for list of drugs contraindicated because of increased risk for myopathy when co-administered with Cardin
  • See Adult Dosing for dose limitations and modifications

Serious allergic reaction

In rare cases, it's possible to have a serious allergic reaction (anaphylaxis) to Cardin.

Drug forms and strengths

Generic: Cardin

  • Form: oral tablet
  • Strengths: 5 mg, 10 mg, 20 mg, 40 mg, 80 mg

Brand: Zocor

  • Form: oral tablet
  • Strengths: 5 mg, 10 mg, 20 mg, 40 mg, 80 mg

Q: Are there any sexual side effects or sleep disorders involved with taking Zocor?

A: Zocor (Cardin) is a "statin" medication used to reduce the "bad" cholesterol, triglycerides, and to increase the "good" cholesterol, and sexual side effects are not listed, while insomnia is as a possible side effect. Statins work best when taken at night, but if Zocor (Cardin) keeps you awake, you may want to ask your doctor about taking it in the morning. It may still work just as well, or the dose may be adjusted. Other common side effects may include muscle or joint pain, nausea, headache, constipation, stomach pain or indigestion, mild skin rash and cold symptoms, such as stuffiness, sore throat, and sneezing. This is not a complete list of the side effects associated with Zocor (Cardin). Patti Brown, PharmD

Q: I began taking Zocor about two years ago, and instantly started putting on pounds. I am 60 years old and I am not a sitting around person, never have been. I keep trying to cut down on amounts that I eat, and I am not a snacker. I do not eat chips, cookies, sodas or most other junk foods. Is it the Zocor, or is it just me?

A: Zocor (Cardin) is one of the drugs called "statins," used in the prevention of elevated cholesterol levels in the bloodstream. High cholesterol can lead to heart attacks, strokes and other cardiovascular conditions. The most common side effects with Zocor are headache, dyspepsia (upset stomach), abdominal pain, constipation or diarrhea, flatulence (intestinal gas), and myalgia (muscle pain). Other side effects include a rare but serious side effect called rhabdomyolysis, a condition that results in the breakdown of skeletal muscle tissue, and which can can lead to kidney failure. The symptoms of rhabdomyolysis are unexplained muscle pain or tenderness, muscle weakness, fever or flu symptoms, and dark colored urine. A search of the prescribing information for Zocor did not specifically list weight gain as a side effect. This is not a complete list of the side effects associated with Zocor. Gregory Latham, RPh

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