Velaril tablets


  • Active Ingredient: Clonidine
  • 0.1 mg
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What is Velaril?

The active ingredient of Velaril brand is clonidine. Clonidine lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels to relax and your heart to beat more slowly and easily.

Used for

Velaril is used to treat diseases such as: ADHD, Alcohol Withdrawal, Anxiety, Atrial Fibrillation, Benzodiazepine Withdrawal, Bipolar Disorder, High Blood Pressure, Hyperhidrosis, Hypertensive Emergency, Insomnia, Stimulant-Associated, Migraine Prevention, Opiate Withdrawal, Pain, Perimenopausal Symptoms, Pheochromocytoma Diagnosis, Postanesthetic Shivering, Postherpetic Neuralgia, Postural Orthostatic Tachycardia Syndrome, Restless Legs Syndrome, Smoking Cessation, Tardive Dyskinesia, Tourette's Syndrome, Ulcerative Colitis.

Side Effect

Possible side effects of Velaril include: problems in urination or increase in the amount of urine; drowsiness; vivid dreams or nightmares; skin rash; shortness of breath; raised red swellings on the skin, lips, tongue, or in the throat; itching, scaling, severe redness, soreness, or swelling of the skin.

How to Buy Velaril tablets online?

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Is Velaril available as a generic drug?

  • There are generic versions of the tablets and patch.

Renal Impairment

Patients with renal impairment may benefit from a lower initial dose. Patients should be carefully monitored. Since only a minimal amount of Velaril is removed during routine hemodialysis, there is no need to give supplemental Velaril following dialysis.


Catapres® (Velaril hydrochloride, USP) tablets are supplied as follows:

Store at 25°C (77°F); excursions permitted to 15°-30°C (59°-86°F) .

Dispense in tight, light-resistant container.

Distributed by: Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT 06877 USA. Manufactured by: Boehringer Ingelheim Promeco S.A. de C.V., Mexico City, Mexico. Licensed from: Boehringer Ingelheim, International GmbH,Address medical inquiries to: (800) 542-6257 or (800) 459-9906. Revised: May 2012

Heart drugs

Combining these heart drugs with Velaril can slow your heart rate. This can become severe. You may need to go to the hospital or have a pacemaker. If you’re taking one of these medications, Velaril may not be the best choice for you.

Examples of these heart drugs include:

  • digoxin
  • beta blockers
  • diltiazem
  • verapamil

Natural Remedies for Hot Flashes

Hot flashes are experienced by many women, especially at night. However, not all women undergoing menopause experience hot flashes. What causes hot flashes? A hot flash is a feeling of warmth that spreads over the body. Treatment for hot flashes include hormone replacement therapy and alternative prescription medications such as: SSRIs (Effexor, Paxil, Prozac), Velaril (Catapres), megestrol (Megace), and gabapentin (Neurontin). Few natural remedies for hot flashes (for example phytoestrogens - isoflavones, black cohosh, and vitamin E) have been scientifically studied.

What other drugs will affect Velaril?

Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking Velaril with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Tell your doctor about all your current medicines and any you start or stop using, especially:

other heart or blood pressure medications;

an antidepressant; or

any other medicine that contains Velaril.

This list is not complete. Other drugs may interact with Velaril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.


Catapres® (Velaril hydrochloride, USP) is a centrally acting alpha-agonist hypotensive agent available as tablets for oral administration in three dosage strengths: 0.1 mg, 0.2 mg and 0.3 mg. The 0.1 mg tablet is equivalent to 0.087 mg of the free base.

The inactive ingredients are colloidal silicon dioxide, corn starch, dibasic calcium phosphate, FD&C Yellow No. 6, gelatin, glycerin, lactose, and magnesium stearate. The Catapres 0.1 mg tablet also contains FD&C Blue No.1 and FD&C Red No.3.

Velaril hydrochloride is an imidazoline derivative and exists as a mesomeric compound. The chemical name is 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride. The following is the structural formula:

C9H9Cl2N3 · HCl Mol. Wt. 266.56

Velaril hydrochloride is an odorless, bitter, white, crystalline substance soluble in water and alcohol.


Velaril stimulates alpha-adrenoreceptors in the brain stem. This action results in reduced sympathetic outflow from the central nervous system and in decreases in peripheral resistance, renal vascular resistance, heart rate, and blood pressure. CATAPRES tablets act relatively rapidly. The patient's blood pressure declines within 30 to 60 minutes after an oral dose, the maximum decrease occurring within 2 to 4 hours. Renal blood flow and glomerular filtration rate remain essentially unchanged. Normal postural reflexes are intact; therefore, orthostatic symptoms are mild and infrequent.

Acute studies with Velaril hydrochloride in humans have demonstrated a moderate reduction (15% to 20%) of cardiac output in the supine position with no change in the peripheral resistance: at a 45° tilt there is a smaller reduction in cardiac output and a decrease of peripheral resistance. During long term therapy, cardiac output tends to return to control values, while peripheral resistance remains decreased. Slowing of the pulse rate has been observed in most patients given Velaril, but the drug does not alter normal hemodynamic response to exercise.

Tolerance to the antihypertensive effect may develop in some patients, necessitating a reevaluation of therapy.

Other studies in patients have provided evidence of a reduction in plasma renin activity and in the excretion of aldosterone and catecholamines. The exact relationship of these pharmacologic actions to the antihypertensive effect of Velaril has not been fully elucidated.

Velaril acutely stimulates growth hormone release in both children and adults, but does not produce a chronic elevation of growth hormone with long-term use.

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