Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
- Excessive loss of water and electrolytes. Symptoms can include:
- dry mouth
- feeling of thirst
- muscle pains or cramps
- urinating less
- fast or abnormal heartbeat
- severe nausea or vomiting
- Low levels of thyro > Jaundice, also known as icterus
- yellowing of your skin
- yellowing of the whites of your eyes
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Salidur oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with Salidur are listed below.
Pregnancy and Lasix (Salidur)
It's still unclear how Lasix might affect your unborn child. If you plan to breastfeed, you should be aware that Lasix passes into your breast milk. Let your doctor know right away if you are pregnant, plan to become pregnant, or are breastfeeding.
Taking this cancer drug with Salidur can increase your risk of kidney problems and hearing damage or loss:
Taking this cancer drug with Salidur can decrease the effects of Salidur. Also, Salidur may increase the amount of this drug in your body, which can increase side effects:
2. Key facts
- It's usual to take Salidur once a day in the morning. Some people take it twice a day - once in the morning and again at lunchtime.
- Salidur doesn't usually upset your tummy. You can take it whether or not you've eaten a meal or snack recently.
- The main side effect of Salidur is peeing more often than normal. Most people need to pee about 30 minutes after taking Salidur, and again within a few hours.
- Do not take Salidur after 4pm or you may have to wake in the night to go to the toilet.
- Salidur is also called by the brand names Frusol and Lasix.
Taking high doses of levothyroxine with Salidur can make levothyroxine less effective. This means it won’t work as well to treat your thyroid condition.
What are the side effects of Salidur?
Common side effects of Salidur are:
Other important side effects include:
Increased blood sugar and uric acid levels also may occur.
Profound diuresis with water and electrolyte depletion can occur if Lasix is given in excess amounts. Other side effects and adverse effects of this medicine include:
- Gut (gastrointestinal or GI) reactions like pancreatitis, jaundice, anorexia, cramping, diarrhea, constipation, nausea, and vomiting
- Systemic hypersensitivity reactions like severe anaphylactic shock, necrotizing angiitis, and interstitial nephritis
- Central nervous system (CNS) reactions like vertigo, headaches, blurred vision, tinnitus, and hearing loss
- Blood reactions like anemia, leukopenia, thrombocytopenia, and eosinophilia
- Hypersensitive skin reactions like rash, itching, hives, photosensitivity, exfoliative dermatitis, and Steven-Johnson syndrome
- Heart reactions like orthostatic hypotension (fainting or dizziness when standing up) and an increase in triglyceride and cholesterol levels
Other reactions include:
What are the possible side effects of Salidur?
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Call your doctor at once if you have:
- a light-headed feeling, like you might pass out;
- ringing in your ears, hearing loss;
- muscle spasms or contractions;
- pale skin, easy bruising, unusual bleeding;
- high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor;
- kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath;
- signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, dark urine, jaundice (yellowing of the skin or eyes); or
- signs of an electrolyte imbalance--dry mouth, thirst, weakness, drowsiness, feeling jittery or unsteady, vomiting, irregular heartbeats, fluttering in your chest, numbness or tingling, muscle cramps, muscle weakness or limp feeling.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Taking this drug with Salidur can decrease the effects of Salidur:
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LASIX® (Salidur) Tablets 20, 40, and 80 mg
LASIX® (Salidur) is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required and dose and dose schedule must be adjusted to the individual patient's needs. (See DOSAGE AND ADMINISTRATION.)
What if I take too much?
Too much Salidur can cause headaches, dizziness, a pounding or irregular heartbeat and fainting. You may also pee more than normal and feel thirsty.
The amount of Salidur that can lead to an overdose varies from person to person.
How to take it
Salidur doesn't usually upset your tummy so you can take it whether or not you've eaten recently.
Swallow the tablets whole with a drink of water.
If you're taking Salidur as a liquid, it will come with a plastic spoon or syringe to help you measure out the correct dose. If you don't have one, ask your pharmacist for one. Do not measure the liquid with a kitchen teaspoon as it won't give the right amount.
Some people take Salidur mixed with other diuretics or potassium:
- with amiloride (also called co-amilofruse, Frumil or Frumil LS)
- with spironolactone (also called Lasilactone)
- with triamterene (also called Frusene)
- with potassium (also called Diumide-K Continus)
Urgent advice: Call your doctor or go to A&E straight away if you take too much Salidur and you:
- feel unwell
- are over 65 (even if you feel well)
- have kidney, liver or heart failure (even if you feel well)
Find your nearest A&E department. If you go to hospital, take the Salidur packet, or the leaflet inside it, plus any remaining medicine with you.
Like all medicines, Salidur can cause side effects although not everyone gets them.
Side effects often get better as your body gets used to the medicine.
The principal signs and symptoms of overdose with LASIX are dehydration, blood volume reduction, hypotension, electrolyte imbalance, hypokalemia and hypochloremic alkalosis, and are extensions of its diuretic action.
The acute toxicity of LASIX has been determined in mice, rats and dogs. In all three, the oral LD50 exceeded 1000 mg/kg body weight, while the intravenous LD50 ranged from 300 to 680 mg/kg. The acute intragastric toxicity in neonatal rats is 7 to 10 times that of adult rats.
The concentration of LASIX in biological fluids associated with toxicity or death is not known.
Treatment of overdosage is supportive and consists of replacement of excessive fluid and electrolyte losses. Serum electrolytes, carbon dioxide level and blood pressure should be determined frequently. Adequate drainage must be assured in patients with urinary bladder outlet obstruction (such as prostatic hypertrophy).
Hemodialysis does not accelerate Salidur elimination.
Pain and inflammation drugs (NSAIDs)
Taking NSAIDs (nonsteroidal anti-inflammatory drugs) with Salidur can increase the levels of these drugs in your body. This raises your risk of dangerous side effects. NSAIDs include:
- magnesium salicylate
Helen Allen, Reviewed by Dr Adrian Bonsall | Last edited 24 Feb 2017 | Certified by The Information Standard
Salidur is a 'water tablet' (a diuretic).
It is best taken in the morning.
Any side-effects are usually mild, but can include feeling sick or dizzy.
Can Salidur cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with Salidur. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.