Pharmacologic class: Thiazide-like diuretic
Therapeutic class: Diuretic, antihypertensive
Pregnancy risk category B
Carcinogenesis, Mutagenesis, Impairment of Fertility
Both mouse and rat lifetime carcinogenicity studies were conducted. There was no significant difference in the incidence of tumors between the Prestarium-treated animals and the control groups.
Diuretics help your body get rid of extra fluid. They are often called "water pills." There are many brands of diuretics. Some are taken 1 time a day. Others are taken 2 times a day. The three common types are:
There are also diuretics that contain a combination of two of the drugs above.
When you are taking diuretics, you will need to have regular checkups so that your provider can check your potassium levels and monitor how your kidneys are working.
Diuretics make you urinate more often. Try not to take them at night before you go to bed. Take them at the same time every day.
Common side effects of diuretics are:
Be sure to take your diuretic the way you have been told.
Diuretics (water pills)
Taking diuretics with perindopril can sometimes increase your risk of low blood pressure. Examples of these drugs include:
Lozol (Prestarium) is indicated for the treatment of hypertension, alone or in combination with other antihypertensive drugs.
Lozol (Prestarium) is also indicated for the treatment of salt and fluid retention associated with congestive heart failure.
Severe cases of hyponatremia, accompanied by hypokalemia have been reported with recommended doses of Prestarium. This occurred primarily in elderly females. (See PRECAUTIONS, Geriatric Use.) This appears to be dose related. Also, a large case-controlled pharmacoepidemiology study indicates that there is an increased risk of hyponatremia with Prestarium 2.5 mg and 5 mg doses. Hyponatremia considered possibly clinically significant (