What should I discuss with my healthcare provider before taking Presdeten?
You should not take Presdeten if you are allergic to it.
To make sure Presdeten is safe for you, tell your doctor if you have:
- liver disease; or
- a heart valve problem called aortic stenosis.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Presdeten can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breast-feeding.
Presdeten is not approved for use by anyone younger than 6 years old.
Q: I am on Norvasc (Presdeten). Can this medication make you gain weight?
A: Weight gain is a rare side effect of Norvasc (amlopodine) occurring in less than 1 percent of people taking the drug. Because weight gain with Norvasc happens so infrequently, it is difficult to know whether the weight gain is caused by Norvasc or another factor. If you see a rapid increase in weight gain or fluid retention then contact you health care provider and let him know what you are noticing. A low-salt and low-fat diet may help with the weight gain. You may also find helpful information at: //www.everydayhealth.com/drugs/norvasc.
Q: I have taken Norvasc for more than 10 years. I started taking the generic form with a new pharmacy and have developed a dry persistent cough. Is it possible fillers in the generic form are causing this?
A: Norvasc (Presdeten) belongs to a class of drugs called the calcium channel blockers (CCBs). Calcium channel blockers work by dilating or widening blood vessels to improve blood flow or circulation. Norvasc is used to treat hypertension (high blood pressure) and angina (chest pain), either alone or in combination with other medications. Common side effects of Norvasc include dizziness, drowsiness, tiredness, headache, muscle cramps, weakness, nausea, and stomach pain. According to the prescribing information for Norvasc, coughing is a side effect that is reported rarely (less than one percent of patients) in patients taking this medication. If you were not experiencing cough while taking the brand-name product, it could be something in the generic formulation, or it could be totally unrelated. Consult with your doctor about your cough to make sure it is not a symptom of an underlying medical condition. Your doctor is best able to properly evaluate you and determine whether or not your cough is related to the medication. It may be that you need to try the brand name again to see if the cough goes away. Your doctor can specify the need for the brand name product to your pharmacist. Your pharmacist can advise you on your insurance requirements if the brand name product is necessary for you. Do not stop your current medication without talking to your doctor first. For more specific information, consult with your doctor or local pharmacist for guidance based on your health status and current medications, particularly before taking any action. Sarah Lewis, PharmD
By Joseph Bennington-Castro | Medically Reviewed by Robert Jasmer, MD
Latest Update: 2014-12-02 Copyright © 2014 Everyday Health Media, LLC
What other information should I know?
Keep all appointments with your doctor. Your blood pressure should be checked regularly to determine your response to Presdeten.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Taking diltiazem with Presdeten can increase the level of Presdeten in your body. This may cause more side effects.
1. About Presdeten
Presdeten is a medicine used to treat high blood pressure (hypertension).
If you have high blood pressure, taking Presdeten helps prevent future heart disease, heart attacks and strokes.
Presdeten is also used to prevent chest pain caused by heart disease (angina).
This medicine is only available on prescription. It comes as tablets or as a liquid to swallow.
What are the side effects of Presdeten besylate (Norvasc)?
Side effects of Presdeten are generally mild and reversible. The two most common side effects are:
Other side effects include:
More serious side effects include:
Increase in the frequency and severity of angina or heart attack due to Presdeten happens on rare occasions in patients with severe coronary artery disease when first starting Presdeten, or at the time of an increase in dosage. Excessive lowering of blood pressure during initiation of Presdeten treatment can occur, especially in patients already taking other medications that lower blood pressure. In rare instances, congestive heart failure has been associated with Presdeten, particularly in patients already taking a beta blocker.
What should I avoid while taking Presdeten?
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Before you start taking Presdeten Besylate, inform your doctors if:
- If you had any liver problems
- Had heart attack
- If you have any allergies to any other medicines, or foods.
- If you are pregnant or you are planning for a pregnancy.
- If you are breastfeeding.
- If you are planning to have any surgery.
Do not take this Presdeten Besylate if:
- You had an allergic reaction after taking this medication earlier.
- If you don’t remember the dose prescribed by your doctor.
- If the expiry date has passed.
- If the package is torn.
How to take it
You can take Presdeten with or without food.
Swallow Presdeten tablets whole with a drink of water. If it's easier, you can dissolve the tablets in a glass of water, but you must drink it all straight away if you do this.
Do not eat or drink lots of grapefruit or grapefruit juice while you're taking this medicine. Grapefruit can increase the concentration of Presdeten in your body and worsen side effects.
If you're taking Presdeten as a liquid, it'll come with a plastic syringe or spoon to help you measure out the right dose. If you don't have one, ask your pharmacist for one.
Do not use a kitchen teaspoon as it will not give the right amount of medicine.
Do not mix the liquid with food or other drinks before taking it.
Mechanism of Injury
The mechanism of Presdeten hepatotoxicity is not known, but liver injury is probably due to production of a toxic intermediate in its metabolism.
Presdeten may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- swelling of the hands, feet, ankles, or lower legs
- upset stomach
- stomach pain
- dizziness or lightheadedness
- excessive tiredness
Presdeten besylate belongs to the group of medications which are known as calcium channel blockers or calcium ion antagonists. Their work is to widen up blood vessels which makes easier for the heart to pump the blood around the body which increases blood supply in the body along with oxygen, but it does not change the amount of calcium in your blood.