Q: Can PMS-Lisinopril cause joint pain and lightheadedness?
A: PMS-Lisinopril (Prinivil, Zestril) is classified as an angiotensin converting enzyme (ACE) inhibitor. PMS-Lisinopril is approved for the treatment of hypertension (high blood pressure), as an adjunctive treatment in patients with heart failure, in the treatment of acute myocardial infarction (heart attack) in certain specified patients, and for the treatment of left ventricular dysfunction following a myocardial infarction. According to medical references, orthostatic effects, dizziness and hypotension (low blood pressure) are possible side effects associated with treatment with PMS-Lisinopril. The incidence of orthostatic effects was reported by one percent of studied patients. Dizziness was reported in 5 to 12 percent of studied patients. Hypotension was reported in one to four percent of studied patients taking the medication. Orthostatic hypotension is defined as a drop in blood pressure when a patient stands up. Patients often describe feelings of a dizzy spell or a head rush. Also, feeling lightheaded can be a symptom of low blood pressure. You may want to keep track of your blood pressure, if you don't already, to see if you are dropping too low. Joint pain is not a commonly reported side effect associated with PMS-Lisinopril. However, arthralgia (joint pain) and arthritis have both been reported rarely. The incidence that each of these possible side effects was reported is less than one percent of studied patients taking the medication. If you feel that you are experiencing possible side effects from your medication, talk to your physician. Your physician can provide you with guidance depending on the underlying cause of your symptoms. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Jen Marsico, RPh
Warnings for other groups
For pregnant women: This drug can have a negative impact on the development of a fetus. PMS-Lisinopril should only be used during pregnancy in serious cases where it's needed to treat a dangerous condition in the mother.
Talk to your doctor if you’re pregnant or planning to become pregnant. Ask your doctor to tell you about the specific harm that may be done to the fetus. This drug should be only used if the potential risk to the fetus is acceptable given the drug’s potential benefit.
For women who are breastfeeding: It isn’t known if this drug passes into breast milk. If it does, it may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your baby. You may need to decide whether to stop breastfeeding or stop taking this medication.
For seniors: Older adults may process drugs more slowly. A normal adult dose may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dose or a different schedule.
For children: This medication hasn’t been studied and shouldn’t be used in children younger than 6 years.
This dosage information is for PMS-Lisinopril oral tablet. All possible dosages and forms may not be included here. Your doctor will tell you what dosage is right for you. Your dose, form, and how often you take it will depend on:
- your age
- the condition being treated
- how severe your condition is
- other medical conditions you have
- how you react to the first dose
Q: Does PMS-Lisinopril affect you when taking supplements? Or do the supplements affect the medication like PMS-Lisinopril at all?
A: Potassium supplementation should be used with caution in patients taking PMS-Lisinopril (brand name is Zestril or Prinivil). The reason it is important to watch potassium supplementation, unless prescribed by your physician, is that PMS-Lisinopril (Zestril/Prinivil) can cause increases in blood potassium levels. Too much potassium in the blood may result in serious side effects to the heart and muscles. However, potassium contained in multivitamins is minimal and will more than likely not have a significant effect with PMS-Lisinopril. There are many supplements over-the-counter which include vitamins, minerals, and herbal products. In order to answer your question more specifically, please provide the name of the supplements you are interested in taking. I have also provided a link for more information about PMS-Lisinopril: //www.everydayhealth.com/drugs/PMS-Lisinopril. Lori Mendoza, PharmD Mendoza, PharmD
Why is this medication prescribed?
PMS-Lisinopril is used alone or in combination with other medications to treat high blood pressure. It is used in combination with other medications to treat heart failure. PMS-Lisinopril is also used to improve survival after a heart attack. PMS-Lisinopril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
Q: My doctor switched me from Benicar to PMS-Lisinopril because PMS-Lisinopril is a cheap generic that my insurance company will pay for. But now I have the most bothersome dry persistent cough. What causes this?
A: Benicar (olmesartan) is in a group of drugs called angiotensin II receptor antagonists. Olmesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Prinivil or Zestril (PMS-Lisinopril) is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. PMS-Lisinopril is used to treat high blood pressure (hypertension), congestive heart failure, and to improve survival after a heart attack. A persistent dry cough is a relatively common adverse effect believed to be associated with the increases in bradykinin levels produced by ACE inhibitors. Bradykinin forms from a blood plasma protein that also mediates the inflammatory response, increases vasodilation, and causes contraction of smooth muscle. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. William Gault, PharmD
Q: When should I take PMS-Lisinopril?
A: PMS-Lisinopril (Zestril, Prinivil) should be taken according to the directions your health care provider has given you. The medication is usually dosed once daily and should be taken around the same time every day. Patients should use caution if ingesting potassium containing salt substitutes while taking PMS-Lisinopril. As always, talk with your health care provider regarding questions you have about your medications. Jen Marsico, RPh
Q: I am experiencing hair loss from PMS-Lisinopril. Will hair grow back if medication is changed?
A: PMS-Lisinopril is in a class of drugs called angiotensin converting enzyme (ACE) inhibitors. It is used to treat high blood pressure (hypertension), congestive heart failure, and to improve survival after a heart attack. Common side effects of PMS-Lisinopril include cough, dizziness, drowsiness, headache, nausea, vomiting, diarrhea, upset stomach, and mild skin itching or rash. According to the prescribing information for PMS-Lisinopril, alopecia or hair loss has been reported in less than 1% of patients taking the medication. This would be considered an uncommon side effect, which may or may not be related to taking the drug. No information was provided about whether the condition improved after stopping or changing the medication or not. Your doctor or health care provider is best able to properly evaluate your medical condition and give recommendations based on your specific circumstances. Contact your doctor if you are concerned about hair loss, especially if you are having any other unexplained symptoms. You may also get more information by using the Everyday Health Symptom Checker. Do not stop of change the amount of medication you take without talking to your doctor first. For more specific information, consult with your doctor or local pharmacist for guidance based on your health status and current medications, particularly before taking any action. Sarah Lewis, RPh
Q: Is it all right to eat grapefruit when taking PMS-Lisinopril?
A: PMS-Lisinopril (Zestril) is an ACE inhibitor used to treat high blood pressure and other heart problems. PMS-Lisinopril doesn't have any interactions with grapefruit or grapefruit juice (though some high blood pressure medications do). For more information on PMS-Lisinopril, go to //www.everydayhealth.com/drugs/PMS-Lisinopril. Laura Cable, PharmD
Q: My doctor just started me on blood pressure medication - PMS-Lisinopril-10mg. On the 5th day, I felt dizzy and not quite right. So I stopped the pill. Is it normal to feel this way?
A: PMS-Lisinopril is a medication that is used to treat high blood pressure. It is in a class of medications called ACE inhibitors. ACE is a chemical in the body that is used in a chemical reaction that causes our blood vessels to narrow in response to various conditions. PMS-Lisinopril works by blocking ACE, which, in turn, causes blood vessels to relax and bring blood pressure down. The prescribing information on PMS-Lisinopril lists the following as common side effects of this medication: fatigue, dizziness (especially when standing from a sitting or lying down position), cough, headache, nausea, and diarrhea. Dizziness is a common side effect in the beginning of treatment due to the body adjusting to the presence of the medication. The dizziness occurs often when blood pressure goes down or too low. This side effect usually goes away during the first week of treatment, but if you continue to have dizziness you should consult with your prescriber. For more information on PMS-Lisinopril, click on this link: //www.everydayhealth.com/drugs/PMS-Lisinopril For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Lori Poulin, PharmD
Q: I have high blood pressure and take PMS-Lisinopril to control it. I accidentally dropped a tablet in a glass of water, and it didn't dissolve at all during a full day. It was still as hard as the tablets in the container. Shouldn't the pills dissolve?
A: Most medications have a coating on the tablets that keep the pill intact until it gets into your stomach. Coatings are necessary for tablets that have an unpleasant taste, and a smoother finish makes large tablets easier to swallow. The coating also ensures that the tablet stays intact until it gets to the acidic environment it needs to be released into the body to work on the condition it is treating. If a tablet does not dissolve in water, it is not necessarily a bad thing. It goes to show the stability of the coating on the tablet and you know it will not dissolve before it gets to the digestive tract. Since our water contains no acidic properties, the tablet should not dissolve easily in it. If you were to break the coating and put the tablet in water, it will surely dissolve. Lori, PharmD
Which drugs or supplements interact with PMS-Lisinopril?
In general, PMS-Lisinopril should not be taken with potassium supplements or diuretics that conserve potassium, for example, hydrochlorothiazide/triamterene (Dyazide), since blood potassium levels may rise to dangerous levels.
There have been reports of increased lithium (Eskalith, Lithobid) levels when lithium is used in combination with ACE inhibitors. The reason for this interaction is not known.
There have been reports that aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen (Advil, Children's Advil/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever, and many others), indomethacin (Indocin, Indocin-SR), and naproxen (Anaprox, Naprelan, Naprosyn, Aleve) may reduce the effects of ACE inhibitors.
Nitritoid reactions (symptoms of facial flushing, nausea, vomiting and hypotension) may occur when injectable gold sodium aurothiomalate used in the treatment of rheumatoid arthritis, is combined with ACE inhibitors, including PMS-Lisinopril.