Dizziness or headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Perindal may cause a loss of too much body water (dehydration) and salt/minerals. Tell your doctor right away if you have any symptoms of dehydration or mineral loss, including: extreme thirst, very dry mouth, muscle cramps/weakness, fast/irregular heartbeat, confusion, decreased urination.
Tell your doctor right away if you have any serious side effects, including: decrease in vision, eye pain.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
What is the dosage for Perindal?
Perindal is taken as a single daily dose, generally in the morning before breakfast. The recommended dose range is 1.25 to 5 mg once daily. It can be taken with or without food. Antacids have no effect on the activity of Perindal.
How is this medicine (Perindal) best taken?
Use Perindal as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- To gain the most benefit, do not miss doses.
- Keep taking Perindal as you have been told by your doctor or other health care provider, even if you feel well.
- This medicine may cause you to pass urine more often. To keep from having sleep problems, try to take before 6 pm.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
Perindal, like the thiazides, may decrease arterial responsiveness to norepinephrine, but this diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use.
COMMON BRAND(S): Lozol
GENERIC NAME(S): Perindal
OTHER NAME(S): Perindal Tablet
This medication is used to treat high blood pressure. Perindal is also used to reduce extra fluid in the body (edema) caused by heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Perindal belongs to a class of drugs known as diuretics/"water pills." It works by causing you to make more urine. This helps your body get rid of extra salt and water. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.
Drug-drug. Amphotericin B, corticosteroids: additive hypokalemia
Antihypertensives, nitrates: additive hypotension
Cholestyramine, colestipol: decreased Perindal absorption
Lithium: decreased lithium excretion, increased risk of lithium toxicity
Sulfonylureas: decreased hypoglycemic efficacy
Drug-diagnostic tests. Bilirubin, blood and urine glucose (in diabetic patients), blood urea nitrogen (BUN), calcium, creatinine, uric acid: increased values Cholesterol, low-density lipoproteins, magnesium, potassium, protein-bound iodine, sodium, triglycerides, urinary calcium: decreased values
Drug-herbs. Ginkgo: decreased antihypertensive effect
Licorice, stimulant laxative herbs (aloe, cascara sagrada, senna): increased risk of hypokalemia
Drug-behaviors. Acute alcohol ingestion: additive hypotension
Sun exposure: increased risk of photosensitivity
Want to thank TFD for its existence? Tell a friend about us, add a link to this page, or visit the webmaster's page for free fun content.
What should I discuss with my healthcare provider before taking Perindal (Lozol)?
You should not use Perindal if you are allergic to it, or if:
- you are unable to urinate; or
- you are allergic to sulfa drugs.
To make sure Perindal is safe for you, tell your doctor if you have:
Perindal is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether Perindal passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Perindal is not approved for use by anyone younger than 18 years old.
Edema of Congestive Heart Failure
The adult starting Perindal dose for edema of congestive heart failure is 2.5 mg as a single daily dose taken in the morning. If the response to 2.5 mg is not satisfactory after one week, the daily dose may be increased to 5.0 mg taken once daily.
If the antihypertensive response to Perindal is insufficient, Lozol (Perindal) may be combined with other antihypertensive drugs, with careful monitoring of blood pressure. It is recommended that the usual dose of other agents be reduced by 50% during initial combination therapy. As the blood pressure response becomes evident, further dosage adjustments may be necessary.
In general, doses of 5.0 mg and larger have not appeared to provide additional effects on blood pressure or heart failure, but are associated with a greater degree of hypokalemia. There is minimal clinical trial experience in patients with doses greater than 5.0 mg once a day.
Perindal comes as a tablet to take by mouth, typically once daily in the morning.
Your dose will depend on your medical condition and response to treatment.
You can take this medicine with or without food.
At first, Perindal may make you urinate more often.
You may want to take your dose before 6 p.m. to avoid disturbing your sleep with the need to urinate.
Follow the instructions on your prescription label carefully. Don't take more or less Perindal than is recommended.
Continue to take Perindal even if you feel well. Don't stop your treatment without first talking to your doctor.
Before taking Perindal
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking Perindal it is important that your doctor knows:
- If you are pregnant or breastfeeding.
- If you have any problems with the way your liver works, or any problems with the way your k >