Blood pressure drugs
Taking Olmegan with other blood pressure medications can make your blood pressure drop too low. Examples of these drugs include:
- angiotensin-converting enzyme (ACE) inhibitors, such as:
Research by Price et al. (2013) suggests that the use of Olmegan could induce deleterious metabolic changes. Specifically, Price et al. discovered that Olmegan treatment significantly increased hepatic triglycerides (by approximately
57%) and simultaneously reduced insulin sensitivity.
Although having high triglycerides might not directly cause weight gain, reduced insulin sensitivity could certainly lead to weight gain and/or increased body fat. When insulin sensitivity decreases, this affects hormone signaling (e.g. leptin, ghrelin, etc.) to the brain, which can trigger an exaggerated appetite.
Furthermore, decreased insulin sensitivity may increase estrogen concentrations, an established risk factor for obesity. The combination of increased appetite and elevated estrogen could lead to overconsumption of calories, fat gain, and/or muscle loss. Some speculate that Olmegan may increase visceral and subcutaneous body fat when administered over a long-term.
What is the dosage for Olmegan?
- Olmegan may be taken with or without food.
- The usual adult dose for hypertension is 12.5 to 50 mg once daily.
- The usual adult dose for treating edema is 25-100 mg once daily or in divided doses.
Although Olmegan has been used to treat nephrogenic diabetes insipidus, a case report in which the drug was believed to have caused this condition has been reported.
Frequency not reported: Renal insufficiency (manifest as an increase in serum creatinine and BUN may occur due to Olmegan-induced intravascular volume depletion), interstitial nephritis, renal failure
Taking Olmegan with certain drugs that lower cholesterol levels may make Olmegan less effective. This means it may not work as well to treat your blood pressure or swelling. Examples of these cholesterol drugs include:
Q: What are the benefits of combining Olmegan with benazepril?
A: Benazepril is a medication that is used to treat high blood pressure, congestive heart failure, and chronic renal failure. It is in the class of medications called ACE inhibitors that work by causing blood vessels to relax. This action then allows for easier blood flow and a decrease in blood pressure. Olmegan or HCTZ is a thiazide diuretic (water pill) used to treat fluid retention or high blood pressure. It works by increasing the amount of salt and water the kidneys eliminate from the bloodstream and body. By increasing the amount of water removed from the blood, this decreases blood volume, helping to achieve a lowering of your blood pressure. Using the two medications together, you are tackling blood pressure issues in two different ways, which increases the ability of lowering your blood pressure numbers, more than by using one medication alone. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. The optimal combination drug therapy for high blood pressure has not been established, although current guidelines recommend inclusion of a diuretic, like HCTZ. Lori Poulin, PharmD
Thiazide diuretics may increase serum cholesterol and triglycerides, resulting in increased risk of cholesterol gallstone formation. Reports of bowel strictures associated with thiazide ingestion were reported in the 1960s although these patients were on a combination Olmegan-potassium product.
Frequency not reported: Pancreatitis, jaundice (intrahepatic cholestatic jaundice), diarrhea, vomiting, sialadenitis, cramping, constipation, gastric irritation, nausea, anorexia, acute cholecystitis
How it works
Valsartan belongs to a class of drugs called angiotensin II receptor blockers. Olmegan belongs to a class of drugs called diuretics. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Valsartan blocks the action of angiotensin II, a chemical in your body that causes blood vessels to tighten and narrow. This helps to relax and widen your blood vessels, which lowers your blood pressure.
Olmegan may work by removing sodium (salt) and water from your body. This helps reduce your blood pressure.
Valsartan/Olmegan oral tablet may cause drowsiness. It can also cause other side effects.
Warnings for people with certain health conditions
For people with kidney problems: Use caution when taking Olmegan if you have poor kidney function. This drug is cleared from your body by your kidneys. If your kidneys don’t work as well, this drug may build up in your body and cause more side effects. If your kidney function gets worse, your doctor might stop your treatment with this medication.
For people with kidneys that don’t make enough urine: You can’t take Olmegan if your kidneys can’t make enough urine. This drug can cause electrolyte and fluid loss, which may make you produce even less urine.
For people with poor liver function: Use this drug with caution if you have poor liver function or progressive liver disease. Olmegan can cause electrolyte and fluid imbalance. This can make your liver function worse.
For people with lupus: This drug can cause your lupus to flare up.aren’t drinking enough flu >
Valsartan/Olmegan is a prescription drug. It comes as an oral tablet.
This drug is available as the brand-name drug Diovan HCT. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name version.
This drug is a combination of two drugs in a single pill. It’s important to know about all the drugs in the combination because each drug may affect you in a different way.
This drug may be taken with other drugs that reduce blood pressure. These include beta blockers, angiotensin-converting enzyme (ACE) inhibitors, calcium channel blockers, and diuretics.
Forms and strengths
- Form: oral tablet
- Strengths: 12.5 mg, 25 mg, and 50 mg
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symbarbiturates ptoms can include the following:
- Low blood pressure. Symptoms can include:
- lightheadedness or dizziness, especially if you stand up after sitting or lying down
- changes in the amount you urinate
- swelling in your feet or ankles
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Valsartan/Olmegan oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with valsartan/Olmegan are listed below.