Metopress tablets


  • Active Ingredient: Metoprolol
  • 100 mg, 50 mg, 25 mg, 12.5 mg
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What is Metopress?

The active ingredient of Metopress brand is metoprolol. Metoprolol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins). Metoprolol tartrate, USP is a white, practically odorless, crystalline powder with a molecular weight of 684.82. It is very soluble in water; freely soluble in methylene chloride, in chloroform, and in alcohol; slightly soluble in acetone; and insoluble in ether. Each tablet for oral administration contains 25 mg, 50 mg, or 100 mg of Metoprolol tartrate and the following inactive ingredients: anhydrous lactose, colloidal silicon dioxide, croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polydextrose, polyethylene glycol, povidone, sodium lauryl sulfate, titanium dioxide and triacetin. In addition, the 50 mg product contains FD&C Blue No. 2 Aluminum Lake, D&C Red No. 27 Aluminum Lake and FD&C Red No. 40 Aluminum Lake and the 100 mg product contains FD&C Blue No. 2 Aluminum Lake as coloring agents.

Used for

Metopress is used to treat diseases such as: Angina, Angina Pectoris Prophylaxis, Atrial Fibrillation, Benign Essential Tremor, Heart Attack, Heart Failure, High Blood Pressure, Left Ventricular Dysfunction, Migraine Prevention, Mitral Valve Prolapse, Premature Ventricular Depolarizations, Supraventricular Tachycardia.

Side Effect

Possible side effects of Metopress include: severe sunburn; passing gas; paleness or cold feeling in the fingertips and toes; clay-colored stools; inability to speak.

How to Buy Metopress tablets online?

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Q: I take Metopress and Coversyl. Could they be causing my problems with gas and belching?

A: Common stomach-related side effects of Metopress are gas, constipation, diarrhea, nausea, stomach pain, and vomiting. Some reported side effects for Coversyl are diarrhea, abdominal pain, nausea, flatulence (gas), and indigestion. Discuss your condition with your doctor if these side effects persist or become worse. For more information, go to // and //

Metopress Interactions

Many drugs may affect the way Metopress works, and Metopress could also affect how other drugs work.

It's very important to let your doctor know about everything you are taking, even illegal drugs and any over-the-counter (OTC) vitamins, herbs, or dietary supplements.

Types of drugs that interact with Metopress include:

  • Antidepressants including bupropion (Wellbutrin), fluoxetine (Prozac, Sarafem), and paroxetine (Paxil)
  • Antimalaria drugs such as hydroxychloroquine
  • Medications used to treat heartburn or other stomach conditions, such as cimetidine (Tagamet) and ranitidine (Zantac)
  • Some heart medications, including clonidine (Catapres), propafenone (Rythmol), and quinidine (Quinaglute, Quinidex)
  • Antihistamines like diphenhydramine (Benadryl)
  • Certain HIV drugs, including ritonavir (Norvir)
  • Some antifungal medications, including terbinafine (Lamisil)
  • Certain drugs used to treat mental illness, including thioridazine (Mellaril)

Q: Does Metopress cause fatigue if taken for a long period of time? I've been taking it for 3-1/2 years now.

A: Metopress belongs to the class of drugs known as beta blockers. According to the package insert, fatigue, mental depression, and drowsiness can occur in patients taking beta-blockers. Fatigue or tiredness was reported in about 10% of patients receiving Metopress during scientific studies of the drug. You are encouraged to report any negative side effects of prescription drugs to your health care practitioner and the Food and Drug Administration (FDA) by visiting, or by calling 1-800-FDA-1088. For more information, please contact your health care provider. Michelle McDermott, PharmD

What is the dosage for Metopress (Lopressor, Toprol XL)?

  • Metopress should be taken before meals or at bedtime.
  • The dose for treating hypertension is 100-450 mg daily in single or divided doses.
  • Angina is treated with 100-400 mg daily in two divided doses.
  • Heart attack (acute myocardial infarction) is treated with three 5 mg injections administered 2 minutes apart followed by treatment with 50 mg oral Metopress every 6 hours for 48 hours. After 48 hours, patients should receive 100 mg orally twice daily for at least 3 months.
  • The dose for congestive heart failure is 25 mg/daily initially. Then the dose is increased every 2 weeks to reach a target dose of 200 mg/daily orally.
  • Hyperthyroidism is treated with 25 to 30 mg by mouth every 6 hours.

Q: Will Metopress cause headaches, or cause sleeplessness?

A: It is always important to be aware of the side effects of a medication so you can recognize the symptoms if they occur. According to the prescribing information available for Metopress, both headache and insomnia (sleeplessness) have been reported as side effects. If these or any other symptoms are bothersome you may want to contact your health-care provider.

Pregnancy Category C

Upon confirming the diagnosis of pregnancy, women should immediately inform the doctor.

Lopressor has been shown to increase postimplantation loss and decrease neonatal survival in rats at doses up to 11 times the maximum daily human dose of 450 mg, when based on surface area. Distribution studies in mice confirm exposure of the fetus when Lopressor is administered to the pregnant animal. These limited animal studies do not indicate direct or indirect harmful effects with respect to teratogenicity (see Carcinogenesis, Mutagenesis, Impairment of Fertility).

There are no adequate and well-controlled studies in pregnant women. The amount of data on the use of Metopress in pregnant women is limited. The risk to the fetus/mother is unknown. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.

Post-Marketing Experience

The following adverse reactions have been identified during post-approval use of TOPROL-XL or immediate-release Metopress. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Cardiovascular: Cold extremities, arterial insufficiency (usually of the Raynaud type), palpitations, peripheral edema, syncope, chest pain and hypotension.

Central Nervous System: Confusion, short-term memory loss, headache, somnolence, nightmares, insomnia, anxiety/nervousness, hallucinations, paresthesia.

Miscellaneous: Musculoskeletal pain, arthralgia, blurred vision, decreased libido, male impotence, tinnitus, reversible alopecia, agranulocytosis, dry eyes, worsening of psoriasis, Peyronie’s disease, sweating, photosensitivity, taste disturbance.

ВїPara cuГЎles condiciones o enfermedades se prescribe este medicamento?

El Metopress se usa solo o en combinaciГіn con otros medicamentos para tratar la presiГіn arterial alta. TambiГ©n se usa para prevenir la angina de pecho (dolor en el pecho) y para tratar los ataques cardГ­acos. El Metopress se usa tambiГ©n en combinaciГіn con otros medicamentos, para tratar la insuficiencia cardГ­aca. El Metopress pertenece a una clase de medicamentos llamados bloqueadores beta. Funciona al relajar los vasos sanguГ­neos y la disminuciГіn de la frecuencia cardГ­aca para mejorar el flujo sanguГ­neo y disminuir la presiГіn arterial.

La hipertensiГіn arterial es una condiciГіn comГєn y cuando no se trata, puede causar daГ±os en el cerebro, el corazГіn, los vasos sanguГ­neos, los riГ±ones y otras partes del cuerpo. El daГ±o a estos Гіrganos puede causar enfermedades del corazГіn, un infarto, insuficiencia cardГ­aca, apoplejГ­a, insuficiencia renal, pГ©rdida de la visiГіn y otros problemas. AdemГЎs de tomar medicamentos, hacer cambios de estilo de vida tambiГ©n le ayudarГЎ a controlar su presiГіn arterial. Estos cambios incluyen comer una dieta que sea baja en grasa y sal, mantener un peso saludable, hacer ejercicio al menos 30 minutos casi todos los dГ­as, no fumar y consumir alcohol con moderaciГіn.

Rated Metopress (Lopressor) for Heart attack Report

This drug, while I suppose it works okay for its purpose, has just too many side effects to make it something that I really want to continue to use. The depression and mood swings are somewhat easier after using the drug for eight weeks, but the fatigue and man, the pain in my shoulders and upper arms is severe, and I'm a barber. I went from the 12.5 twice a day to the timed-release form, and I recommend taking this one later at night, as it is pretty much a donkey punch at first. I also take lisinopril, Plavix, a baby aspirin and Lipitor after heart attack and cardiac arrest about seven weeks ago. BP is traditionally very normal, and now is quite low, to my way of thinking. 116/66 last evening. To sum up, I think Metopress has just too many side effects overall, and I wish I could be put on something else or have my dosage reduced.

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Rated Metopress (Lopressor) for Hypertension Report

My anxiety is so bad and it kept my bp up so I was prescribed this 50mg once a day and my life is back to normal

Rated Metopress (Lopressor) for Atrial Fibrillation Report

Taken for afib. 25 once a day. Stopped from be able to orgasm right away. Felt tired. I cut it in half. Was a bit better. 4th cardiologist told me to stop taking it and see what happens. If I go into afib he said to take one. Am on Xarelto so if I go into afib I am protected. First day and I feel better. These doctors say the exact same thing to each person. Never treat you like a human being. Question everything they tell you to do. Go to multiple specialists. Many of these drugs they put you on you do not need to take. I have to take a stinkin blood thinner. But, I do not have to take this crap. First Doc put me on a big dose of Crestor. I asked if he knew my cholesterol numbers. He did not and said it did not matter. My numbers are good. Crap darn near crippled me. Stop taking it also. Remember quality of life not quantity.

Q: I take Metopress XL as a preventative for high blood pressure, is it necessary?

A: Metopress belongs to a class of medications called beta blockers. Metopress is usually prescribed to be used alone or in combination with other medications for the treatment of high blood pressure. Metopress is also used for preventing angina (chest pain) and for improving survival after a heart attack. The Metopress extended-release (long-acting) formulation is usually prescribed to be used in combination with other medications for treating heart failure. Metopress helps by relaxing blood vessels and slowing heart rate to improve blood flow and lower blood pressure. Studies show that Metopress may cause side effects such as tiredness, depression, dizziness or lightheadedness, nausea, vomiting, dry mouth, stomach pain, gas or bloating. Your healthcare provider will reevaluate your drug treatment and make any adjustments to your regimen. Your healthcare provider will be able to give you guidance based on your overall health status and your current drug regimen. You can also find helpful information in our health centers by accessing the link below: //, // and // Anissa Lee, RPh


Concomitant administration of hydralazine may inhibit presystemic metabolism of Metopress leading to increased concentrations of Metopress.

Metopress is a prescription drug that doctors may use to treat heart issues, such as high blood pressure, heart attack, and heart failure. The most common form is Metopress succinate, which people can buy under the brand name Toprol-XL. Metopress may also refer to Metopress tartrate, which has the brand name Lopressor.

Metopress often causes side effects so some people may wish to consider using alternative medications.

Importantly, no one taking Metopress should stop taking the drug unless they are following direct orders from a doctor. Even if the drug causes side effects, the person will need to come off the drug gradually or transfer to a new drug.

Q: I take 1/2 pill twice a day of Metopress. I had a heart attack a year ago, but they do not know why I had a heart attack and they don't know what kind, only that my enzymes were elevated. What happens if I forget to take my Metopress while on a 3-day vacation. Is it a drug I cannot skip on?

A: According to the package insert for Metopress, patients should be warned against interruption or discontinuation of therapy without the advice of their health care provider. If you are away on vacation, a local pharmacy may be able to help if you do not have your medication with you. Call the local pharmacy and speak with the pharmacist. This information is solely educational. It's important to consult with your physician or health care provider about any specific questions regarding your medical conditions or medications; particularly before taking any action. // Kristen Dore, PharmD

Q: I have an apparent drug reaction (very bad rash) and my doctor thinks it is from Metopress due to having a "punch" from my skin in two places. The rash sometimes itches, but mostly just look horrible. Could the Metopress be causing the skin rash? She has had me discontinue the drug and I am taking an oral steroid for about three weeks. I just began taking it.

A: Metopress (Lopressor) is a beta-blocker used to treat high blood pressure and other heart conditions as directed by your doctor. The most common side effects with Metopress are low blood pressure, low pulse, dizziness, fatigue, depression, and diarrhea. Other potential side effects with Metopress include pruritus (itching), rash, sensitivity to the sun and worsening of psoriasis. This is not a complete list of the side effects associated with Metopress. Laura Cable, PharmD

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