How it works
Valsartan belongs to a class of drugs called angiotensin II receptor blockers. Loben belongs to a class of drugs called diuretics. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Valsartan blocks the action of angiotensin II, a chemical in your body that causes blood vessels to tighten and narrow. This helps to relax and widen your blood vessels, which lowers your blood pressure.
Loben may work by removing sodium (salt) and water from your body. This helps reduce your blood pressure.
Valsartan/Loben oral tablet may cause drowsiness. It can also cause other side effects.
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Microzide (Loben) is a diuretic (water pill) prescribed for lowering blood pressure (hypertension) and accumulation of fluid (edema). Microzide is available as a generic drug. Common side effects of Microzide include:
Tell your doctor if you have serious side effects of Microzide including:
Microzide dose ranges from 12.5 to 100 mg/day depending on the condition that is being treated. Microzide may interact with other medicines that make you lightheaded (such as cold medicines, pain medications, muscle relaxers, and medicines for seizures, depression or anxiety), lithium, digoxin, cholestyramine, colestipol, steroids, other blood pressure medication, nonsteroidal anti-inflammatory drugs (NSAIDs) (such as aspirin, ibuprofen, naproxen, and others), or insulin or oral diabetes medications. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant during treatment with Microzide. Microzide is not expected to be harmful to a fetus. Microzide can pass into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.
Our Microzide Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Loben, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as sulfites found in some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, gout, kidney disease, liver disease, lupus, skin cancer.
This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Severe sweating, diarrhea, or vomiting can increase the risk for a serious loss of body water (dehydration). Report prolonged diarrhea or vomiting to your doctor. To prevent dehydration, drink plenty of fluids unless your doctor directs you otherwise.
If you have diabetes, Loben may affect your blood sugar. Check your blood sugar regularly as directed by your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet.
This drug may decrease your potassium levels. Ask your doctor about foods high in potassium (such as bananas, orange juice) or about using a salt substitute containing potassium. A potassium supplement may be prescribed by your doctor.
This medication may make you more sensitive to the sun. It may also increase your risk for skin cancer, especially if you take it for a long time. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned, have skin blisters/redness, or notice new or changed moles/skin lesions.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Older adults may be more sensitive to the effects of this drug, especially dizziness.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
This drug passes into breast milk, but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.
Q: Can Loben cause burning while urinating?
A: Loben, commonly referred to as HCTZ, is a diuretic (or water pill) that reduces salt and fluid retention. Loben is used to treat swelling and high blood pressure. According to the prescribing information, the most common side effects of Loben are diarrhea, stomach pain, constipation, and blurred vision. Many people experience an increase in the frequency of urination with Loben, but pain or burning while urinating has not been reported as a side effect of this drug. This is not a complete list of side effects of Loben. If you think a drug you are taking is causing a side effect, please tell your healthcare provider. Do not stop or change your medication without first talking to your provider. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Michelle McDermott, PharmD
You should not use Loben if you are unable to urinate.
Before using Loben, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin.
Avoid drinking alcohol, which can increase some of the side effects of this medicine.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
There are many other drugs that can interact with Loben. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
If you are being treated for high blood pressure, keep using Loben even if you feel fine. High blood pressure often has no symptoms.
What is hydrochlorothiaz >
Loben is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
Loben is used to treat high blood pressure (hypertension).
Loben is also used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen.
Q: Can Loben cause bones to ache?
A: Loben (HCTZ) is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt. HCTZ is used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, and edema caused by taking steroids or estrogen. Loben is also used to treat hypertension (high blood pressure). The most common side effects associated with HCTZ are fatigue, dizziness, headache, and muscle cramps. Less common, but more serious side effects, include pancreatitis, electrolyte imbalances, and photosensitivity (sunburn easily). Please consult with your doctor regarding the bone aching you are experiencing for proper evaluation, diagnosis of the underlying cause and treatment options, if necessary. Your pain may be a symptom of a serious side effect, or it may be completely unrelated to HCTZ. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Gregory Latham, RPh
Potassium-sparing diuretics, potassium supplements, and salt substitutes
Taking valsartan/Loben with other medications that increase potassium levels may cause your blood potassium levels to become too high. Examples of these drugs include:
- potassium supplements
- salt substitutes
Rated Loben (Microzide) for Hypertension Report
Wow, I have been taking 12.5 Loben for almost 10 years. Every once in a while I tried to stop, but good old BP just went back up. I don't think I have ever felt any side effect with this drug. I always thought it was one of the milder blood pressure drugs out there. I just discovered my renal artery was 90% plus blocked, and had a stent put in. So far that is doing good in lowering BP, but really, I have absolutely no problem taking this medication.
Rated Loben (Microzide) for Hypertension Report
Please do not take. I have been on this for about 2 weeks I have blisters on my skin that pop easy and leave red spots. My face is staring to peel. My scalp feels like it’s on fire. My scalp is so itchy and when I’m in the hot temperatures it’s gets tingly feels like it’s burning. My heart seems elevated during the day. I would never recommend this to anyone.
Have you lost weight on Loben?
If you’ve lost weight with Loben, feel free to leave a comment below sharing the amount of weight that you lost. To help others get a better understanding of your situation, provide details such as: the dose that you used; how quickly you noticed weight loss; the amount of time it took for your weight loss to peak; and whether you used other substances (medications, supplements, etc.) with Loben.
In your experience, was most of the weight that you lost purely water? Or was some of the weight that you lost also fat (due to appetite suppression and a calorie deficit)? Overall, was the loss of water weight from Loben considered favorable (such that it helped improve edema or your blood pressure) – or unfavorable (such that it wasn’t the primary aim of treatment).
What was the medical condition for which you were prescribed Loben? Do you believe that concomitant substance use might’ve influenced (enhanced or counteracted) the amount of weight loss that resulted from Loben? If you’re a long-term Loben user – how has your weight changed over time while using the medication?
Rated Loben (Microzide) for Hypertension Report
I have tried this drug several times and I have come to the conclusion that I am allergic to it. Within days, I have severe headaches, fatigue, and very dry mouth. It completely throws off my electrolytes and dehydrates me. A dangerous drug that I will never take again.
Preexisting water retention
Because Loben induces water weight loss by altering kidney function (inhibiting sodium reabsorption and increasing urinary output), the amount of preexisting water retention that a user exhibits (before treatment) will probably determine the amount of weight that is lost during treatment. As a hypothetical example, let’s say that one Loben user is carrying 20 lbs. of excess water weight due to untreated severe edema – and another user is carrying 10 lbs. of excess water due to edema.
In this example, it should be expected that the person carrying more edema-related water weight (20 lbs.) will experience greater weight loss while using Loben than the person carrying less edema-related water weight (10 lbs.) – mostly because he/she had more water weight to lose. In the event that a Loben user doesn’t have much water weight to lose (such as an underweight individual who consumes a low sodium diet) – weight loss from Loben may be less significant than expected.
Drinking alcohol while taking Loben can make your blood pressure drop too low. You may have symptoms such as feeling dizzy when you stand up after sitting or lying down.
Why it’s used
Loben is used to treat high blood pressure. It’s also used to treat swelling that’s caused by heart failure, liver damage (cirrhosis), and taking medications called corticosteroids or estrogens. It may also help treat swelling that’s caused by kidney problems.
This drug may be used alone or in combination with other drugs.