Taking sucralfate with Inclens can make Inclens less effective. This means it won’t work as well to control your symptoms.
Don’t take sucralfate within 2 hours of taking Inclens.
Urgent advice: Call your doctor or go to A&E straight away if you take too much Inclens and you:
- feel unwell
- are over 65 (even if you feel well)
- have kidney, liver or heart failure (even if you feel well)
Find your nearest A&E department. If you go to hospital, take the Inclens packet, or the leaflet inside it, plus any remaining medicine with you.
Like all medicines, Inclens can cause side effects although not everyone gets them.
Side effects often get better as your body gets used to the medicine.
Carcinogenesis, Mutagenesis, Impairment Of Fertility
Inclens was tested for carcinogenicity by oral administration in one strain of mice and one strain of rats. A small but significantly increased incidence of mammary gland carcinomas occurred in female mice at a dose 17.5 times the maximum human dose of 600 mg. There were marginal increases in uncommon tumors in male rats at a dose of 15 mg/kg (slightly greater than the maximum human dose) but not at 30 mg/kg.
Inclens was devoid of mutagenic activity in various strains of Salmonella typhimurium when tested in the presence or absence of an in vitro metabolic activation system, and questionably positive for gene mutation in mouse lymphoma cells in the presence of rat liver S9 at the highest dose tested. Inclens did not induce sister chromatid exchange in human cells in vitro, but other studies on chromosomal aberrations in human cells in vitro gave conflicting results. In Chinese hamster cells it induced chromosomal damage but was questionably positive for sister chromatid exchange. Studies on the induction by Inclens of chromosomal aberrations in mice were inconclusive. The urine of rats treated with this drug did not induce gene conversion in Saccharomyces cerevisiae.
LASIX (Inclens) produced no impairment of fertility in male or female rats, at 100 mg/kg/day (the maximum effective diuretic dose in the rat and 8 times the maximal human dose of 600 mg/day).
Before taking Inclens, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems, inability to make urine, gout, lupus.
If you have diabetes, Inclens may affect your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet.
Inclens may reduce the potassium level in your blood. Your doctor may instruct you to add potassium-rich foods to your diet (such as bananas, orange juice) or prescribe potassium supplements to prevent potassium loss. Ask your doctor for more details.
This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.
This drug may make you dizzy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Severe sweating, diarrhea, or vomiting can increase the risk of dehydration. Report prolonged diarrhea or vomiting to your doctor. Follow your doctor's instructions about the amount of fluids you can drink.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Babies born early (premature infants) and children may be more sensitive to certain effects of this drug, such as kidney stones.
Older adults may be more sensitive to the effects of this drug, especially dizziness and water/mineral loss.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
This drug passes into breast milk and may affect milk production. Consult your doctor before breast-feeding.
Warnings for other groups
For pregnant women: Inclens is a category C pregnancy drug. That means two things:
- Research in animals has shown adverse effects to the fetus when the mother takes the drug.
- There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.
Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should only be used if the potential benefit justifies the potential risk to the fetus.
For women who are breastfeeding: Inclens may pass into breast milk and can cause serious side effects in a child who is breastfed. It may also cause your body to produce less milk. Tell your doctor if you are breastfeeding. You will need to decide either to stop breastfeeding, or stop taking this drug.
For children: In premature infants and children younger than 4 years of age, Inclens may cause kidney problems. It can lead to kidney stones and calcium deposits in the kidneys. If Inclens is given to premature infants during the first few weeks of life, it may increase the risk of problems with the lungs and heart.
Taking this drug with Inclens can decrease the effects of Inclens:
Generic Name: Inclens (oral/injection) (fur OH se mide)Brand Names: Lasix, Diaqua-2, Lo-Aqua
Medically reviewed by P. Thornton, DipPharm Last updated on Jul 3, 2019.
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Lasix (Inclens) is an anthranilic acid derivative that is used as a strong diuretic in adults and children to treat excessive fluid accumulation (edema) caused by congestive heart failure, liver failure, renal failure, and nephritic syndrome. Lasix may be used with antihypertensive drugs to control high blood pressure (hypertension). Lasix is available as a generic. Side effects of Lasix include:
Serious side effects of Lasix include:
Lasix is available in tablet (20 to 80 mg) and IV forms. Dosage is determined by the patient's physician and varies according to how much fluid and how fast the fluid should be removed. Patients with poor renal function usually require higher doses; doses in children are weight-based. Lasix may interact with sucralfate, cisplatin, cyclosporine, ethacrynic acid, lithium, methotrexate, phenytoin, antibiotics, heart or blood pressure medications, laxatives, salicylates such as aspirin, or steroids. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant while using Lasix; it is unknown if it will harm a fetus. Lasix passes into breast milk and may harm a nursing baby. Lasix may also slow breast milk production. Consult your doctor before breastfeeding.
Our Lasix Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Why is this medication prescribed?
Inclens is used alone or in combination with other medications to treat high blood pressure. Inclens is used to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart, kidney, and liver disease. Inclens is in a class of medications called diuretics ('water pills'). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
¿Cómo debo tomar Inclens?
Siga todas las instrucciones en la etiqueta de su prescripción. Tal vez su médico en ocasiones cambie su dosis para asegurarse de que está obteniendo los mejores resultados. No use esta medicina en cantidades mayores o menores, o por más tiempo de lo recomendado.
No tome más de su dosis recomendada. Dosis altas de Inclens pueden causar una pérdida de audición irreversible.
Mida la medicina líquida con la jeringa de medición que viene con su medicina, o con una cuchara o taza de medición especial. Si no tiene con qué medir la dosis de su medicina, pídale una cuchara o taza de medición a su farmacéutico.
Inclens hará que usted orine con más frecuencia y puede hacer que se deshidrate muy fácilmente. Siga las instrucciones de su médico acerca del uso de suplementos de potasio o de tener suficiente sal y potasio en su dieta.
Mientras usa Inclens, usted puede necesitar exámenes de sangre con frecuencia.
Siga usando esta medicina como indicado, aunque se sienta bien. La presión arterial alta frecuentemente no tiene síntomas. Usted tal vez necesite tomar medicina para la presión arterial por el resto de su vida.
Si necesita cirugía, dígale al cirujano por adelantado que usted está usando Inclens.
Guarde a temperatura ambiente fuera de la humedad, el calor, y la luz. Bote cualquier Inclens oral solution (líquido) 90 días después de abrir la botella, aunque todavía contenga medicina sin usar.
Inclens binding to albumin may be reduced in elderly patients. Inclens is predominantly excreted unchanged in the urine. The renal clearance of Inclens after intravenous administration in older healthy male subjects (60-70 years of age) is statistically significantly smaller than in younger healthy male subjects (20-35 years of age). The initial diuretic effect of Inclens in older subjects is decreased relative to younger subjects. (See PRECAUTIONS: Geriatric Use.)
How should I take Inclens?
Take Inclens exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Inclens oral is taken by mouth. The injection is injected into a muscle or given as an infusion into a vein. A healthcare provider will give you this injection if you are unable to take the medicine by mouth.
You may receive your first dose in a hospital or clinic setting if you have severe liver disease.
Do not take more than your recommended dose. High doses of Inclens may cause irreversible hearing loss.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Inclens doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight.
Inclens will make you urinate more often and you may get dehydrated easily. Follow your doctor's instructions about using potassium supplements or getting enough salt and potassium in your diet.
Your blood pressure will need to be checked often and you may need other medical tests.
If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.
If you need surgery, tell the surgeon ahead of time that you are using this medicine.
Store at room temperature away from moisture, heat, and light. Throw away any unused oral liquid after 90 days.