Rated Hidroclorotiazida (Microzide) for Hypertension Report
I was prescribed 12.5mg of HCTZ in the spring of 2019 and tolerated the dose well but my dr. wanted to lower my BP more and doubled the dose to 25mg. Several weeks later I started experiencing leg pain and he did a BMP blood test and my potassium had dropped only 1/10 of a point. I think it is due the higher dose of HCTZ and have gone back to 12.5mg (with his approval) to see if it helps the leg pain. I have tried other BP meds and seem to always have some sort of problematic side effect. Also trying to raise my potassium level too.
Taking valsartan/Hidroclorotiazida with this drug can increase your risk of gout.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Hidroclorotiazida is a medication prescribed for a variety of conditions. It was approved by the FDA in 1959. It is used most often to treat high blood pressure. It is also prescribed to treat edema, which is excessive fluid accumulation in the body. As with most medications, Hidroclorotiazida side effects can be serious or just irritating, and many patients experience no side effects at all.
Generally, doctors will only prescribe a medication if they feel that the positive aspects of the treatment outweigh any potential negatives. Keep this in mind as you review Hidroclorotiazida side effects. If you are taking or planning to take Hidroclorotiazida, learn about the possible side effects and know when to contact your physician.
There are rare case reports of Hidroclorotiazida-induced immune hemolytic anemia. The following illustrates a fatal case:
A 53-year-old man with hypertension developed nausea, vomiting, diarrhea, and progressive anorexia and weakness associated with scleral icterus, anemia with spherocytosis, dark red urine with proteinuria, bilirubinuria, hemoglobinuria, and elevated lactic dehydrogenase levels 18 months after beginning Hidroclorotiazida and methyldopa. Haptoglobin was less than 50 mg per dl. Direct and indirect Coombs tests were positive. The patient died suddenly; autopsy revealed no obvious cause of death, left ventricular hypertrophy, and mild coronary atherosclerosis.
Rare (less than 0.1%): Allergic vasculitis, hemolytic anemia, development of a rash histologically identical to subacute cutaneous lupus
Rated Hidroclorotiazida (Microzide) for Hypertension Report
I have lost the last 7 and a half months of my life. I began taking this medication and within a few days I started getting dizzy and had severe loss of balance. I am on thyroid medication and attributed it to the lower dose. I then had two incidents where I fell and hit my head. I spoke to my doctor and he raised my thyroid, but I kept getting worse. The muscle spasms in my left foot, the pain at times, was so bad that I couldn't walk. I still am unable to stand on the foot for very long. The whole left side of my body is weak. I have a pinched nerve in my neck from falling and hitting my head. I'm spending a small fortune in trying everything I can to stop this madness. I worked out 5 days a week and haven't been able to. Due to thyroid issues, I'm putting on weight, which has sent mme in a downward spiral. Anyway, the list goes on. Now I'm the lucky recipient of having a nerve conductive test. I'm not able to work. Who knows when this madness will end.
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symbarbiturates ptoms can include the following:
- Low blood pressure. Symptoms can include:
- lightheadedness or dizziness, especially if you stand up after sitting or lying down
- changes in the amount you urinate
- swelling in your feet or ankles
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Valsartan/Hidroclorotiazida oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with valsartan/Hidroclorotiazida are listed below.
What is Hydrochlorothiaz >
Hidroclorotiazida is the generic form of the brand-name drug Microzide.
It's a prescription diuretic ("water pill") that's used to treat high blood pressure and other conditions.
Hidroclorotiazida is designed to help eliminate the excessive fluid accumulation and swelling that’s often caused by congestive heart failure, cirrhosis of the liver, chronic kidney failure, corticosteroid medications and nephrotic syndrome.
Hidroclorotiazida is the second most commonly prescribed antihypertensive in the United States. Despite its popularity, researchers do not have a clear grasp as to how it works to lower blood pressure.
Most blood pressure lowering medications, including Hidroclorotiazida, are prescribed together with other hypertensive products, along with dietary restrictions, exercise, and, in some cases, weight loss.
Hidroclorotiazida may also be prescribed to treat calcium-containing kidney stones because it decreases the amount of calcium excreted by the kidneys in the urine, thus reducing the amount of calcium available to form stones.
Although Hidroclorotiazida is approved to treat edema in cirrhosis of the liver, it’s rarely used for that purpose because other diuretics are considered more effective.
The Food and Drug Administration (FDA) approved Hidroclorotiazida in 1959. It's manufactured by several companies, including Mylan, Vintage Pharmaceuticals, and Watson Labs.
In addition to Microzide, Hidroclorotiazida is available as:
I have stage 3 kidney failure due to years of untreated high blood pressure and over use of ibuprophen. I take atenolol, lisinopril, Hidroclorotiazida, amlodipine, lipitor and synthroid. I want to know if Hidroclorotiazida, lisinopril and lipitor are good or bad for kidney function?