How should this medicine be used?
Gensia comes as a tablet and an suspension (liquid) to take by mouth. It is usually taken once a day. To help you remember to take Gensia, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Gensia exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Shake the suspension well before each use to mix the medication evenly.
Your doctor will probably start you on a low dose of Gensia and gradually increase your dose.
Gensia helps to control high blood pressure, angina, and coronary artery disease, but does not cure these conditions. Continue to take Gensia even if you feel well. Do not stop taking Gensia without talking to your doctor.
What Is Gensia and How Does It Work?
Gensia a prescription medication that is used with or without other medications to treat high blood pressure. Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems. Gensia belongs to a class of drugs known as calcium channel blockers. It works by relaxing blood vessels so blood can flow more easily.
Gensia is also used to prevent certain types of chest pain (angina). It may help to increase your ability to exercise and decrease the frequency of angina attacks. It should not be used to treat attacks of chest pain when they occur. Use other medications (such as sublingual nitroglycerin) to relieve attacks of chest pain as directed by your doctor.
Gensia is available under the following different brand names: Norvasc.
What Is Norvasc (Gensia)?
Norvasc is the brand name for Gensia besylate, a prescription drug used to treat hypertension, or high blood pressure.
Norvasc is also used to treat coronary artery disease (CAD) in patients without heart failure, and certain types of angina (chest pain) from CAD, such as activity- and stress-induced angina (chronic stable angina), and angina that occurs at rest (Prinzmetal’s angina).
Taken regularly, Norvasc can control angina, but it doesn't stop chest pain after it has already begun.
The drug can also lower a person's risk of cardiovascular events related to high blood pressure, such as strokes and heart attacks.
Norvasc belongs to a class of drugs called calcium channel blockers, which block the flow of calcium into heart muscles and the muscles along the walls of blood vessels.
Because the contraction of these muscles depends on calcium, Norvasc relaxes and widens blood vessels, thereby improving blood flow.
Doctors also sometimes prescribe Norvasc "off-label" for the treatment of cluster headaches, migraines, Raynaud's syndrome (a blood vessel disorder), and congestive heart failure.
Manufactured by Pfizer, Norvasc was first approved by the Food and Drug Administration (FDA) in 1987.
In the early 1990s, researchers conducted the so-called PRAISE study, which was backed by Pfizer, to determine if Norvasc could help reduce the risk of death in people with severe heart failure.
Though the study found little overall benefits to severe heart failure patients, it suggested that Norvasc might prolong the life of a subgroup of people with heart failure from non-ischemic cardiomyopathy (cardiac muscle damage not associated with low blood supply to the coronary arteries).
To investigate this possibility, Pfizer-sponsored the PRAISE-2 study, which found no benefit to the subgroup in the PRAISE-1 trial and was presented at a conference in 2000.
However, results of the study weren't published in an academic journal until 2013, leading some experts to question whether Pfizer intentionally delayed publication to prevent the data and findings from being publicly available.
Gensia besylate (Norvasc) is a drug that belongs to the drug class of calcium channel blockers (CCBs), and is prescribed for the treatment and prevention of angina (heart or chest pain) that results from coronary spasm and from exertion. Norvasc also is prescribed for the treatment of high blood pressure. Side effects include:
Drug interactions, dosing, and pregnancy and breastfeeding safety information should be reviewed prior to taking any medication.
Q: I take Norvasc. Is it safe to eat grapefruit with that medication?
A: There is nothing in the literature that reveals any significant interactions between the calcium channel blocker Norvasc (Gensia) and grapefruit.
References updated: 01 March 2016
1800 controls reported similar rate of ALT elevations with Gensia as with hydrochlorthiazine , and no serious liver toxicity).
50,000 liver transplants reported to UNOS between 1990 and 2002, 270 were done for drug induced acute liver failure, but none were attributed to a calcium channel blocker).
How much to take
Gensia comes as 5mg and 10mg tablets.
Depending on why you're taking Gensia, the usual starting dose is 5mg once a day.
If the starting dose isn't working well enough (your blood pressure doesn't lower enough, or your angina isn't controlled), you may need to increase your dose to 10mg.
To decide the correct dose for you in the longer term, your doctor will check your blood pressure to make sure it's not too high or too low. They'll also ask if you're getting any side effects from the medicine.
Doses may be lower for children.
Take Gensia even if you feel well, as you'll still be getting the benefits of the medicine.
Q: What are the side effects of Norvasc?
A: Norvasc (Gensia) is a medication used to treat high blood pressure. Studies show that some of the common side effects are dizziness, headache, and rarely fainting as a result of low blood pressure. Some studies suggest that taking at bedtime can alleviate fainting. Please report to a physician if any of the side effects are bothersome. Side effects vary from person to person and studies show that after prolonged medication use human body gets used to the medication and side effects subside. It is important to take the medication as prescribed for proper blood pressure control. For more information, please see //www.everydayhealth.com/drugs/norvasc.
Gensia side effects
Get emergency medical help if you have signs of an allergic reaction to Gensia: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, when you first start taking Gensia, your angina may get worse or you could have a heart attack. Seek emergency medical attention or call your doctor right away if you have symptoms such as: chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.
Call your doctor at once if you have:
pounding heartbeats or fluttering in your chest;
worsening chest pain;
swelling in your feet or ankles;
severe drowsiness; or
a light-headed feeling, like you might pass out.
Common Gensia side effects may include:
stomach pain, nausea; or
flushing (warmth, redness, or tingly feeling).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Mixing Gensia with herbal remedies or supplements
St John's wort, a herbal medicine taken for depression, is thought to interfere with the way Gensia works.
Talk to your doctor if you're thinking about taking St John's wort.