Warnings for people with certain health conditions
For people with kidney problems: Fursemid is removed from your body by your kidneys. If you have kidney problems, more of the drug may stay in your body longer. This could lead to dangerous side effects, including very low blood pressure. Your doctor may start you on a lower dose of this drug. Your doctor may also monitor how well your kidneys are working to make sure Fursemid is safe for you to take.
For people with liver problems: If you have liver problems such as cirrhosis or ascites, it’s best to receive Fursemid in the hospital. Fursemid can cause very low electrolyte levels, which can cause serious liver damage and loss of brain function. (Electrolytes are minerals that help control the fluid balance in your body and help with other important functions.) Your doctor will monitor you closely.
For people with diabetes: Fursemid can make it harder to control your blood sugar (glucose) levels. Before taking this drug, be sure your doctor knows you have diabetes.
For people with bladder disorders: If you have severe problems with emptying your bladder completely, Fursemid can make your condition worse. Before taking this drug, be sure your doctor knows you have a bladder disorder.
For people with thyroid problems: High doses (over 80 mg) of Fursemid can cause low levels of thyroid hormones. Be sure to tell your doctor about your thyroid problems before you start taking Fursemid.
Taking this drug with Fursemid can increase your risk of gouty arthritis:
The principal signs and symptoms of overdose with LASIX are dehydration, blood volume reduction, hypotension, electrolyte imbalance, hypokalemia and hypochloremic alkalosis, and are extensions of its diuretic action.
The acute toxicity of LASIX has been determined in mice, rats and dogs. In all three, the oral LD50 exceeded 1000 mg/kg body weight, while the intravenous LD50 ranged from 300 to 680 mg/kg. The acute intragastric toxicity in neonatal rats is 7 to 10 times that of adult rats.
The concentration of LASIX in biological fluids associated with toxicity or death is not known.
Treatment of overdosage is supportive and consists of replacement of excessive fluid and electrolyte losses. Serum electrolytes, carbon dioxide level and blood pressure should be determined frequently. Adequate drainage must be assured in patients with urinary bladder outlet obstruction (such as prostatic hypertrophy).
Hemodialysis does not accelerate Fursemid elimination.
What is the dosage for Fursemid?
The usual starting oral dose for treatment of edema in adults is 20-80 mg as a single dose. The same dose or an increased dose may be administered 6-8 hours later. Doses may be increased 20-40 mg every 6-8 hours until the desired effect occurs. The effective dose may be administered once or twice daily. Some patients may require 600 mg daily.
The starting oral dose for children is 2 mg/kg. The starting dose may be increased by 1-2 mg/kg every 6 hours until the desired effect is achieved. Doses greater than 6 mg/kg are not recommended.
The recommended dose for treating hypertension is 40 mg twice daily. The dose of other blood pressure medications should be reduced by half when Fursemid is added.
Why is this medication prescribed?
Fursemid is used alone or in combination with other medications to treat high blood pressure. Fursemid is used to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart, kidney, and liver disease. Fursemid is in a class of medications called diuretics ('water pills'). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
Mood stabilizers (lithium)
Taking lithium with Fursemid can increase the levels of lithium in your body. This raises your risk of side effects from lithium.
Qué otras drogas afectarán a furosem >
Tomar esta medicina con alcohol o con otras drogas que le causen sueño puede empeorar este efecto. Pregúntele a su médico antes de tomar Fursemid con una pastilla para dormir, narcótico para el dolor, relajante muscular, o medicina para la ansiedad, depresión, o convulsiones.
Fursemid puede hacerle daño a sus riñones. Este efecto aumenta cuando usted también usa ciertas otras medicinas, incluyendo: antivirales, quimioterapia, antibióticos inyectables, medicina para los trastornos intestinales, medicina para prevenir el rechazo de órgano trasplantado, medicamentos inyectables para tratar la osteoporosis, y algunas medicinas para el dolor o la artritis (incluyendo aspirin, Tylenol, Advil, y Aleve).
Dígale a su médico todas las medicinas que usa, y cualquiera que comience o deje de usar, especialmente:
- chloral hydrate;
- digoxin, digitalis;
- phenytoin; o
- medicina para el corazón o la presión arterial.
Esta lista no está completa. Otras drogas pueden interactuar con Fursemid, incluyendo medicinas que se obtienen con o sin receta, vitaminas, y productos herbarios. No todas las interacciones posibles aparecen en esta guía del medicamento.
¿Dónde puedo obtener más información?
Su farmacéutico le puede dar más información acerca de Fursemid.
Immediate action required: Call 999 or go to A&E if:
- you get a skin rash that may include itchy, red, swollen, blistered or peeling skin
- you're wheezing
- you get tightness in the chest or throat
- you have trouble breathing or talking
- your mouth, face, lips, tongue or throat start swelling
You could be having a serious allergic reaction and may need immediate treatment in hospital.
These are not all the side effects of Fursemid. For a full list see the leaflet inside your medicines packet.
You can report any suspected side effects to the UK safety scheme.
Pregnancy and Lasix (Fursemid)
It's still unclear how Lasix might affect your unborn child. If you plan to breastfeed, you should be aware that Lasix passes into your breast milk. Let your doctor know right away if you are pregnant, plan to become pregnant, or are breastfeeding.
LASIX (Fursemid) Tablets 20 mg are supplied as white, oval, monogrammed tablets in Bottles of 100 (NDC 0039-0067-10) and 1000 (NDC 0039-0067-70). The 20 mg tablets are imprinted with “Lasix®” on one side.
LASIX Tablets 40 mg are supplied as white, round, monogrammed, scored tablets in Bottles of 100 (NDC 0039-0060-13), 500 (NDC 0039-0060-50), and 1000 (NDC 0039-0060-70). The 40 mg tablets are imprinted with “Lasix® 40” on one side.
LASIX Tablets 80 mg are supplied as white, round, monogrammed, facetted edge tablets in Bottles of 50 (NDC 0039-0066-05) and 500 (NDC 0039-0066-50). The 80 mg tablets are imprinted with “Lasix® 80” on one side.
Note: Dispense in well-closed, light-resistant containers. Exposure to light might cause a slight discoloration. Discolored tablets should not be dispensed.
Tested by USP Dissolution Test 2
Store at 25° C (77° F); excursions permitted to 15 -30° C (59 -86° F).
Manufactured for: sanofi-aventis U.S. LLC Bridgewater, NJ 08807. A Sanofi Company.. Revised: Mar 2016
What other drugs will affect Fursemid?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
If you also take sucralfate, take your Fursemid dose 2 hours before or 2 hours after you take sucralfate.
Tell your doctor about all your other medicines, especially:
another diuretic, especially ethacrynic acid;
cancer medicine, such as cisplatin;
heart or blood pressure medicine; or
This list is not complete. Other drugs may interact with Fursemid, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.