Carpiaton tablets


  • Active Ingredient: Spironolactone
  • 100 mg, 25 mg
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What is Carpiaton?

The active ingredient of Carpiaton brand is spironolactone. Spironolactone is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. Spironolactone is practically insoluble in water, soluble in alcohol, and freely soluble in benzene and in chloroform. Inactive ingredients include calcium sulfate, corn starch, flavor, hypromellose, iron oxide, magnesium stearate, polyethylene glycol, povidone, and titanium dioxide. Spironolactone tablets are effective in lowering the systolic and diastolic blood pressure in patients with primary hyperaldosteronism. It is also effective in most cases of essential hypertension, despite the fact that aldosterone secretion may be within normal limits in benign essential hypertension. Through its action in antagonizing the effect of aldosterone, Spironolactone tablets inhibit the exchange of sodium for potassium in the distal renal tubule and helps to prevent potassium loss. Spironolactone tablets have not been demonstrated to elevate serum uric acid, to precipitate gout, or to alter carbohydrate metabolism. The pharmacological activity of Spironolactone metabolites in man is not known. However, in the adrenalectomized rat the antimineralocorticoid activities of the metabolites C, TMS, and HTMS, relative to Spironolactone, were 1.10, 1.28, and 0.32, respectively. Relative to Spironolactone, their binding affinities to the aldosterone receptors in rat kidney slices were 0.19, 0.86, and 0.06, respectively. In humans, the potencies of TMS and 7-α-thiospirolactone in reversing the effects of the synthetic mineralocorticoid, fludrocortisone, on urinary electrolyte composition were 0.33 and 0.26, respectively, relative to Spironolactone. However, since the serum concentrations of these steroids were not determined, their incomplete absorption and/or first-pass metabolism could not be ruled out as a reason for their reduced in vivo activities. Spironolactone and its metabolites are more than 90% bound to plasma proteins. The metabolites are excreted primarily in the urine and secondarily in bile. The effect of food on Spironolactone absorption (two 100 mg Aldactone tablets) was assessed in a single-dose study of 9 healthy, drug-free volunteers. Food increased the bioavailability of unmetabolized Spironolactone by almost 100%. The clinical importance of this finding is not known.

Used for

Carpiaton is used to treat diseases such as: Acne, Alopecia, Edema, Gender Dysphoria, Heart Failure, High Blood Pressure, Hirsutism, Hypokalemia, Primary Hyperaldosteronism, Primary Hyperaldosteronism Diagnosis.

Side Effect

Possible side effects of Carpiaton include: heartburn; chills; headache; Abdominal or stomach cramping, burning, or tenderness; shakiness and unsteady walk; numbness or tingling in the hands, feet, or lips; lower back or side pain; decrease in urine output or decrease in urine-concentrating ability.

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Before taking Carpiaton

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking Carpiaton it is important that your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breastfeeding.
  • If you have k >

Is Carpiaton safe to take if I'm pregnant or breastfeeding?

  • There are no adequate studies in pregnant women. Aldactone may be harmful if used for treating gestational hypertension (high blood pressure during pregnancy).
  • An active metabolite of Aldactone is secreted in breast milk. To avoid adverse effects in the newborn, mothers should avoid breastfeeding while taking Aldactone.

Rated Carpiaton (Aldactone) for Acne Report

I’ve been taking 100 mg of Spirinolactone for 3 months. Since I started it my face has cleared up tremendously. I started getting small bumps on my neck which also went away. However the side effects aren’t worth it. I’ve experienced bloating, frequent urination, decrease in thirst, constipation, constant full feeling, binge eating, and a chest rash that looked like 20 or more tiny pimples. I’ve had to resort to ex lax for the first time in my life, which is very painful I’m finding. Also you can’t get pregnant while on this. I think this works the way birth control does because it has hormones in it. If that’s the case after birth control I got post pill acne pretty severely and I’m not looking forward to that again. This drug is not something I want to take for years just to keep my acne at bay, the side effects are too much.

Rated Carpiaton (Aldactone) for Acne Report

On my 4th month of taking this drug at 25mg,I started to have side effects. Vertigo, headaches/dizziness. It cleared up my acne and I also lost 10lbs of water weight. My cycle is irregular since being of it. Every person is different. Just do the research and very careful. I’m currently taking a vitamin prescription by my dermatologist . So far so good.

Drugs and supplements that increase potassium blood levels

Taking certain medications with Carpiaton can increase the amount of potassium in your body to unsafe levels. Examples of these drugs include:

  • angiotensin-converting enzyme (ACE) inhibitors, such as:
    • benazepril
    • captopril
    • enalapril
    • fosinopril
    • imidapril
    • moexipril
    • perindopril
    • quinapril
    • ramipril
    • trandolapril
  • irbesartan
  • losartan
  • olmesartan
  • telmisartan
  • valsartan
  • aliskiren
  • heparin and low molecular weight heparin (LMWH)
  • potassium supplements
  • triamterene
  • eplerenone (This drug should not be used with Carpiaton.)
  • Michael Stewart, Reviewed by Sid Dajani | Last edited 27 Aug 2019 | Certified by The Information Standard

    Carpiaton is a diuretic, also known as a 'water tablet'.

    It will make you go to the toilet more often to pass urine.

    The most common side-effect is a mild stomach upset. This is not usually troublesome.

    Other uses for this medicine

    Carpiaton also is used in combination with other medicines to treat precocious puberty (a condition causing children to enter puberty too soon, resulting in the development of sexual characteristics in girls usually younger than 8 years of age and in boys usually younger than 9 years of age) or myasthenia gravis (MG, a disease in which the nerves do not function properly and patients may experience weakness; numbness; loss of muscle coordination; and problems with vision, speech, and bladder control). Carpiaton also may be used to treat certain female patients with abnormal facial hair. Talk to your doctor about the possible risks of using this medication for your condition.

    This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

    Rated Carpiaton (Aldactone) for Acne Report

    It worked VERY well clearing my skin, only taking about 3 months to see a complete difference ! (I've only been on it for 4 months) .However it has caused me to have nausea really bad & vomiting alot more frequent . Sucks I'm gonna have to resort to something else because it's becoming too much of an issue .

    Rated Carpiaton (Aldactone) for Acne Report

    I’m not one to write reviews but I thought I’d give my two cents on this medication. Throughout my teenage years, I had clear skin. Once I hit 21, my skin grew a hatred for me. I had painful cystic acne all on my chin and jaw line. After trying literally everything except accutane, I decided to try this. I was skeptical at first but I figured I had nothing to lose. I started off with 25mg a day and saw no improvement so I switched to 50mg a day. That was 3 months ago. I now have the same clear skin I had in my teenage years, I just have some scarring left from old acne spots but those are now fading. You NEED to take this with food because it will make you very nauseous if you don’t. I have not gained or lost any weight. I do get headaches sometimes if I don’t drink enough water because this is a diuretic. With that said, you will pee A LOT. So remember to keep drinking fluids. My breasts have gotten slightly larger but that’s a huge perk for me. Overall, this medicine is well worth the side effects I’ve experienced and it saved my skin.

    Why is this medication prescribed?

    Carpiaton is used to treat certain patients with hyperaldosteronism (the body produces too much aldosterone, a naturally occurring hormone); low potassium levels; heart failure; and in patients with edema (fluid retention) caused by various conditions, including liver, or kidney disease. It is also used alone or with other medications to treat high blood pressure. Carpiaton is in a class of medications called aldosterone receptor antagonists. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine but reduces the loss of potassium from the body.

    High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

    COMMON BRAND(S): Aldactone

    GENERIC NAME(S): Carpiaton

    OTHER NAME(S): Carpiaton Tablet

    Carpiaton is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems.

    This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone).

    Carpiaton is known as a "water pill" (potassium-sparing diuretic).

    What is the dosage for Carpiaton?

    • Aldactone may be taken with or without food. The dosage range is 25-400 mg daily in single or divided doses.
    • The initial dose for treating edema in adults is 100 mg daily as a single dose or divided doses. The dose may be adjusted after 5 days based on response. The recommended dose range is 25 to 200 mg daily. The initial dose should be continued for at least 5 days before increasing the dose. If there is no adequate response after 5 days, a second diuretic may be added.
    • The dose for treating high blood pressure (hypertension) is 50 to 100 mg daily in single or divided doses.
    • The dose for treating hypokalemia is 25 to 100 mg daily.

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