Why it’s used
Benetor is used to treat high blood pressure. It may be used alone or in combination with other drugs to lower your blood pressure.
Uses of Benetor:
- It is used to treat high blood pressure.
- It may be given to you for other reasons. Talk with the doctor.
Dosage for Benicar
Benicar is available in strengths of 5, 20, or 40 mg of Benetor medoxomil tablets. The usual recommended starting dose is 20 mg per day but dosage in pediatric patients needs to be calculated for each individual.
What are some things I need to know or do while I take Benetor?
- Tell all of your health care providers that you take Benetor. This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how Benetor affects you.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
- Check your blood pressure as you have been told.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- If you are taking a salt substitute that has potassium in it, a potassium-sparing diuretic, or a potassium product, talk with your doctor.
- If you are on a low-salt or salt-free diet, talk with your doctor.
- If you also take colesevelam, take it at least 4 hours after you take Benetor.
- If you are taking lithium, talk with your doctor. You may need to have your blood work checked more closely while you are taking it with Benetor.
- Talk with your doctor before using OTC products that may raise blood pressure. These include cough or cold drugs, diet pills, stimulants, ibuprofen or like products, and some natural products or aids.
- Talk with your doctor before you drink alcohol.
- Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss.
- Tell your doctor if you have too much sweat, fluid loss, throwing up, or loose stools. This may lead to low blood pressure.
- This medicine may not work as well in black patients. Talk with the doctor.
Other uses for this medicine
Benetor is also sometimes used to treat heart failure (condition in which the heart is unable to pump enough blood to the rest of the body) and diabetic nephropathy (kidney disease in people with diabetes and high blood pressure). Talk to your doctor about the possible risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
MDL 2606 – District of New Jersey
Lawsuits related to Benicar and other Benetor drug products created by Daiichi Sankyo were centralized into a multidistrict litigation (MDL) case in the United States District Court for the District of New Jersey. At its peak, the Benicar MDL had more than 2,300 cases assigned to it, each of which was filed by an individual who suffered from side effects of the blood pressure drug (or a surviving family member).
In June 2018, most of the lawsuits in the Benicar MDL were resolved after 97% of participants agreed to participate in the settlement proposed by Daichii Sankyo in August 2017. A handful of plaintiffs who rejected the settlement are still pursuing their cases in the District of New Jersey.
Benicar and Sprue-Like Enteropathy
Several medical studies have investigated the connection between Benicar and sprue-like enteropathy, a severe form of chronic diarrhea that can lead to substantial weight loss and intestinal problems. A 2012 report from the Mayo Clinic found a connection between Benetor and sprue-like enteropathy, as did additional studies published in 2013 and 2014.
Injury reports and studies led the FDA to approve label changes for Benicar, Benicar HCT, Azor and Tribenzor in 2013. The new warning labels warned that patients who developed sprue-like enteropathy symptoms should stop taking Benicar if no other cause for their condition could be found. Other related side effects have also been listed in Benicar lawsuits.
If you also take cholestyramine or colestipol, avoid taking these medications within 4 hours before or 4 hours after you take hydrochlorothiazide and Benetor.
Do not use potassium supplements or salt substitutes while you are taking hydrochlorothiazide and Benetor, unless your doctor has told you to.
Drinking alcohol can further lower your blood pressure and may cause side effects.
Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids.
Tell your doctor about all your current medicines and any you start or stop using, especially:
- any other blood pressure medications;
- insulin or oral diabetes medicine;
- lithium; or
- NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
This list is not complete. Other drugs may interact with hydrochlorothiazide and Benetor, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Benicar . Parsippany, New Jersey: Daiichi Sankyo, Inc.;2013 July.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed November 6, 2009.
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