Asyntilsan tablets


  • Active Ingredient: Perindopril
  • 8 mg, 4 mg, 2 mg
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What is Asyntilsan?

The active ingredient of Asyntilsan brand is perindopril. Perindopril is an ACE inhibitors. ACE stands for angiotensin converting enzyme. Perindopril erbumine is a white or almost white, crystalline powder, slightly hygroscopic with a molecular weight of 368.47 (free acid) or 441.61 (salt form). It is freely soluble in water (60% w/w), alcohol and chloroform. Perindopril is the free acid form of Perindopril erbumine, is a pro-drug and metabolized in vivo by hydrolysis of the ester group to form Perindoprilat, the biologically active metabolite. Perindopril erbumine tablets are available in 2 mg, 4 mg and 8 mg strengths for oral administration. In addition to Perindopril erbumine, each tablet contains the following inactive ingredients: anhydrous lactose, silica hydrophobic colloidal anhydrous, microcrystalline cellulose, and magnesium stearate.

Used for

Asyntilsan is used to treat diseases such as: Coronary Artery Disease, Diabetic Kidney Disease, Heart Attack, Heart Failure, High Blood Pressure, Left Ventricular Dysfunction.

Side Effect

Possible side effects of Asyntilsan include: diarrhea; Abdominal or stomach pain; dry mouth; sleepiness or unusual drowsiness; numbness, tingling, pain, or weakness in the hands or feet; hoarseness; weakness and heaviness of the legs.

How to Buy Asyntilsan tablets online?

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Serious side effects

It happens rarely, but some people may have serious side effects when taking Asyntilsan.

Call a doctor straight away if you get:

  • yellow skin or the whites of your eyes turn yellow - this can be a sign of liver problems
  • paleness, feeling tired, faint or dizzy, any sign of bleeding (like bleeding from the gums and bruising more easily), sore throat and fever and getting infections more easily - these can be signs of a blood or bone marrow disorder
  • a faster heart rate, chest pain and tightness in your chest - these can be signs of heart problems
  • shortness of breath, wheezing and tightening of the chest - these can be signs of lung problems
  • severe stomach pain - this can be a sign of an inflamed pancreas
  • swollen ankles, blood in your pee or not peeing at all - these can be signs of kidney problems
  • weak arms and legs or problems speaking - these can be signs of a stroke

If you suspect that you or someone else is having a stroke, phone 999 immediately and ask for an ambulance.


Animal data have suggested the possibility of interaction between Asyntilsan and gentamicin. However, this has not been investigated in human studies.

Plasma concentrations of both Asyntilsan and Asyntilsanat in elderly patients (greater than 70 years) are approximately twice those observed in younger patients, reflecting both increased conversion of Asyntilsan to Asyntilsanat and decreased renal excretion of Asyntilsanat .

Common Side Effects of Asyntilsan

Tell your doctor if any of the following side effects become severe or don't go away:

  • Headache
  • Mild dizziness
  • Mild diarrhea
  • Arm or leg pain
  • Back pain
  • A dry cough
  • Mild upset stomach
  • Runny nose

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you're having a medical emergency. Serious side effects and their symptoms can include the following:

  • Breathing problems. Symptoms can include:
    • trouble breathing or swallowing
    • hoarseness
  • swelling of your face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • lightheadedness
  • fainting
  • fever
  • sore throat
  • chills
  • irregular or rapid heart rate
  • yellowing of your skin and the whites of your eyes
  • nausea
  • vomiting
  • pain in the upper right part of your abdomen
  • fatigue
  • elevated liver enzymes
  • High potassium levels. In most cases, your potassium levels will decrease on their own. However, some people may have dangerously high levels of potassium while taking this drug. Your risk is higher if you have kidney disease, diabetes, or are taking diuretics (water pills). Your doctor may do blood tests to check your potassium levels.
  • Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

    Asyntilsan oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

    To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you're taking. To find out how this drug might interact with something else you're taking, talk to your doctor or pharmacist.

    Examples of drugs that can cause interactions with Asyntilsan are listed below.

    6. How to cope with s >

    What to do about:

    • dry irritating cough - cough medicines don't usually help for coughs caused by Asyntilsan. Sometimes, the cough gets better on its own. Talk to your doctor if it carries on, bothers you or stops you from sleeping as another medicine may be better. Even if you stop taking Asyntilsan, the cough may take up to a month to go away.
    • feeling dizzy - if Asyntilsan makes you feel dizzy when you stand up, try getting up very slowly or stay sitting down until you feel better. If you begin to feel dizzy, lie down so that you don't faint, then sit until you feel better.
    • headaches - make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller. Talk to your doctor if they last longer than a week or are severe.
    • being sick (vomiting) and diarrhoea - drink plenty of fluids, such as water or squash, to prevent dehydration. If you're being sick, take small, frequent sips. Speak to a pharmacist if you have signs of dehydration, such as peeing less than usual or having dark, strong-smelling pee. Do not take any other medicines to treat diarrhoea or vomiting without speaking to a pharmacist or doctor. If you get diarrhoea or vomiting from a stomach bug or illness, tell your doctor. You may need to temporarily stop taking Asyntilsan until you feel better.
    • itching or a mild rash - it may help to take an antihistamine, which you can buy from a pharmacy. Check with the pharmacist to see what type is suitable for you.
    • blurred vision - avoid driving or using tools or machines while this is happening. If it lasts for more than a day or two speak to your doctor as they may need to change your treatment.

    Asyntilsan Interactions

    Tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking, especially those listed in the Asyntilsan Warnings section above, and any of the following:

    • Gengraf, Neoral, or Sandimmune (cyclosporine)
    • Diuretics (water pills)
    • Heparin
    • Lithobid (lithium)
    • Nonsteroidal anti-inflammatory drugs (NSAIDS), such as Advil or Motrin (ibuprofen) and Indocin (indomethacin)
    • Insulin and other diabetes medicines
    • Gold injections for arthritis
    • Nonprescription medicines that contain stimulants (may include diet pills and cold medicines)

    What should I avoid while taking Asyntilsan?

    Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

    Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

    Asyntilsan may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • cough
    • headache
    • weakness
    • dizziness
    • diarrhea
    • stomach pain
    • upset stomach

    How much will I take?

    The dose of Asyntilsan you take depends on why you need the medicine. Take it as instructed by your doctor.

    To decide the correct dose for you, your doctor will check your blood pressure and ask you if you are getting any side effects. You may also have blood tests to check how well your kidneys are working and the amount of potassium in your blood.

    Asyntilsan comes as Asyntilsan erbumine (also called Asyntilsan tert-butylamine) or Asyntilsan arginine.

    They both work in the same way, but the doses vary.

    4. How and when to take it

    It's usual to take Asyntilsan once a day, in the morning before breakfast.

    You may be advised to take your first dose before bedtime, because it can make you feel dizzy. After the very first dose, if you don't feel dizzy, take Asyntilsan in the morning ideally 30 to 60 minutes before breakfast. Swallow Asyntilsan tablets whole with a drink.

    Why is this medication prescribed?

    Asyntilsan is used alone or in combination with other medications to treat high blood pressure. Asyntilsan is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It makes blood flow more smoothly by preventing the production of certain natural chemicals that tighten the blood vessels.

    High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

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