Amlopol tablets


  • Active Ingredient: Amlodipine
  • 10 mg, 5 mg, 2.5 mg
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What is Amlopol?

The active ingredient of Amlopol brand is amlodipine. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and improves blood flow.

Used for

Amlopol is used to treat diseases such as: Angina, Coronary Artery Disease, Heart Failure, High Blood Pressure, Migraine Prevention, Raynaud's Syndrome.

Side Effect

Possible side effects of Amlopol include: decreased sexual performance or desire; cough; loss of appetite; diarrhea; unusual bleeding or bruising.

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Case 1. Acute hepatitis-like syndrome attributed to amlopidine.

A 76 year old man with diabetes and end-stage renal disease developed jaundice while on long term nifedipine therapy (60 mg daily for

3 years) for hypertension. He was taking insulin, but no other medications. He had no risk factors for viral hepatitis and did not drink alcohol. Serum bilirubin was 2.5 mg/dL and rose over the next few months to 6.2 mg/dL. Tests for acute hepatitis A, B and C were negative and abdominal ultrasonography showed a normal liver and gallbladder. Nifedipine was stopped and he recovered rapidly. Several months later, Amlopol was started (10 mg daily) and within 6 weeks, he developed jaundice and a cholestatic pattern of serum enzyme elevations. Once Amlopol was stopped, liver tests improved and were normal three weeks later.

What should I avoid while taking Amlopol?

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

1. About Amlopol

Amlopol is a medicine used to treat high blood pressure (hypertension).

If you have high blood pressure, taking Amlopol helps prevent future heart disease, heart attacks and strokes.

Amlopol is also used to prevent chest pain caused by heart disease (angina).

This medicine is only available on prescription. It comes as tablets or as a liquid to swallow.

Mood stabilizers

Taking these drugs with Amlopol/benazepril can increase the levels of these medications in your body. This means that you may have more side effects. Examples of these drugs include:

What is the most important information I should know about Amlopol?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.


This drug must be stored at the right temperature:

  • Store Amlopol at room temperature between 59°F and 86°F (15°C and 30°C).
  • Store this drug in its original container and keep it tightly closed.
  • Keep this drug away from light.
  • Don’t store this medication in moist or damp areas, such as bathrooms.

3. Who can and can't take Amlopol

Amlopol can be taken by adults and children aged 6 years and over.

Amlopol is not suitable for some people.

To make sure Amlopol is safe for you, tell your doctor if you:

  • have had an allergic reaction to Amlopol or any other medicines in the past
  • are trying to get pregnant, are already pregnant or you're breastfeeding
  • have liver or kidney disease
  • have heart failure or you have recently had a heart attack

How much to take

Amlopol comes as 5mg and 10mg tablets.

Depending on why you're taking Amlopol, the usual starting dose is 5mg once a day.

If the starting dose isn't working well enough (your blood pressure doesn't lower enough, or your angina isn't controlled), you may need to increase your dose to 10mg.

To decide the correct dose for you in the longer term, your doctor will check your blood pressure to make sure it's not too high or too low. They'll also ask if you're getting any side effects from the medicine.

Doses may be lower for children.

Q: What are the side effects of Norvasc?

A: Norvasc (Amlopol) is a medication used to treat high blood pressure. Studies show that some of the common side effects are dizziness, headache, and rarely fainting as a result of low blood pressure. Some studies suggest that taking at bedtime can alleviate fainting. Please report to a physician if any of the side effects are bothersome. Side effects vary from person to person and studies show that after prolonged medication use human body gets used to the medication and side effects subside. It is important to take the medication as prescribed for proper blood pressure control. For more information, please see //

Before you start taking Amlopol Besylate, inform your doctors if:

  • If you had any liver problems
  • Had heart attack
  • If you have any allergies to any other medicines, or foods.
  • If you are pregnant or you are planning for a pregnancy.
  • If you are breastfeeding.
  • If you are planning to have any surgery.

Do not take this Amlopol Besylate if:

  • You had an allergic reaction after taking this medication earlier.
  • If you don’t remember the dose prescribed by your doctor.
  • If the expiry date has passed.
  • If the package is torn.

What are the side effects of Amlopol besylate (Norvasc)?

Side effects of Amlopol are generally mild and reversible. The two most common side effects are:

Other side effects include:

More serious side effects include:

Increase in the frequency and severity of angina or heart attack due to Amlopol happens on rare occasions in patients with severe coronary artery disease when first starting Amlopol, or at the time of an increase in dosage. Excessive lowering of blood pressure during initiation of Amlopol treatment can occur, especially in patients already taking other medications that lower blood pressure. In rare instances, congestive heart failure has been associated with Amlopol, particularly in patients already taking a beta blocker.

How to use Amlopol BESYLATE

Read the Patient Information Leaflet if available from your pharmacist before you start taking Amlopol and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily.

Some brands of the liquid form of this medication should be shaken before use, while other brands should not be shaken before use. Check the manufacturer's information or ask your pharmacist for specific directions. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your medical condition and response to treatment. Your doctor may gradually increase your dose. Follow your doctor's instructions carefully.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.

If used for angina, this medication must be taken regularly to be effective. It should not be used to treat angina when it occurs. Use other medications (such as sublingual nitroglycerin) to relieve an angina attack as directed by your doctor. Consult your doctor or pharmacist for details.

Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings remain high or increase, chest pain continues or worsens).


References updated: 01 March 2016

1800 controls reported similar rate of ALT elevations with Amlopol as with hydrochlorthiazine , and no serious liver toxicity).

50,000 liver transplants reported to UNOS between 1990 and 2002, 270 were done for drug induced acute liver failure, but none were attributed to a calcium channel blocker).

Medical Definition of Amlopol

Note: Trademarks for preparations containing Amlopol include Azor, Caduet, Exforge, Lotrel, Norvasc, and Tribenzor.

Q: I have taken Norvasc for more than 10 years. I started taking the generic form with a new pharmacy and have developed a dry persistent cough. Is it possible fillers in the generic form are causing this?

A: Norvasc (Amlopol) belongs to a class of drugs called the calcium channel blockers (CCBs). Calcium channel blockers work by dilating or widening blood vessels to improve blood flow or circulation. Norvasc is used to treat hypertension (high blood pressure) and angina (chest pain), either alone or in combination with other medications. Common side effects of Norvasc include dizziness, drowsiness, tiredness, headache, muscle cramps, weakness, nausea, and stomach pain. According to the prescribing information for Norvasc, coughing is a side effect that is reported rarely (less than one percent of patients) in patients taking this medication. If you were not experiencing cough while taking the brand-name product, it could be something in the generic formulation, or it could be totally unrelated. Consult with your doctor about your cough to make sure it is not a symptom of an underlying medical condition. Your doctor is best able to properly evaluate you and determine whether or not your cough is related to the medication. It may be that you need to try the brand name again to see if the cough goes away. Your doctor can specify the need for the brand name product to your pharmacist. Your pharmacist can advise you on your insurance requirements if the brand name product is necessary for you. Do not stop your current medication without talking to your doctor first. For more specific information, consult with your doctor or local pharmacist for guidance based on your health status and current medications, particularly before taking any action. Sarah Lewis, PharmD

By Joseph Bennington-Castro | Medically Reviewed by Robert Jasmer, MD

Latest Update: 2014-12-02 Copyright © 2014 Everyday Health Media, LLC


Taking Amlopol/benazepril with sacubitril, which is used with valsartan to treat high blood pressure and heart failure, raises your risk of angioedema (serious swelling). You should not use Amlopol/benazepril within 36 hours of using sacubitril.

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